Patents by Inventor Thomas F. Cullen

Thomas F. Cullen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7090808
    Abstract: Apparatus and method for testing one or more sterilization indicators (e.g., biological indicators or chemical indicators) or other articles by contacting them under controlled sterilization conditions with a flowing antimicrobial gas containing hydrogen peroxide vapor are disclosed. This invention also provides apparatus and method for testing sterilization processes that use a flowing antimicrobial gas containing hydrogen peroxide vapor under controlled sterilization conditions, or for testing materials for such processes under controlled sterilization conditions, or for testing both such processes and such materials under controlled sterilization conditions. There can be an essentially square-wave contact of the sterilization indicators or other articles with the antimicrobial gas (i.e.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: August 15, 2006
    Assignee: Pharmaceutical Systems, Inc.
    Inventors: Ross A. Caputo, Robert R. Reich, Jr., Robert J. Thrash, Jimmy Fisher, Davoud Khorzad, Thomas F. Cullen
  • Patent number: 6794649
    Abstract: Methods are disclosed for determining the monotonic functional relationship between (A) the integrated absorbance of spectral energy within a spectral region of interest of an analyte (i) that decomposes during the time experimental spectral data for determining the relationship are being obtained, or (ii) whose spectral data are pressure sensitive at pressures below a given pressure, or (iii) that decomposes during the time the spectral data are being obtained and whose spectral data are pressure sensitive and (B) the concentration of the analyte before decomposition commences. Methods are also disclosed for using the monotonic functional relationship to determine the concentration of the analyte in an unknown from the integrated absorbance of spectral energy within the spectral region of interest for the unknown.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: September 21, 2004
    Assignee: Pharmaceutical Systems, Inc.
    Inventors: Robert J. Thrash, Thomas F. Cullen, Davoud Khorzad, Jimmy Fisher
  • Patent number: 6746652
    Abstract: Apparatus and method for producing at high efficiency vaporization a precisely controllable, continuously adjustable gas-phase flow of a vaporizable liquid (e.g., hydrogen peroxide) in a carrier gas (e.g., air) are disclosed. The gas-phase product flow can be substantially continuous, low-temperature, unsaturated with respect to the vaporized vaporizable liquid, and of substantially constant vaporized vaporizable liquid concentration as a function of time. Fine particles of the vaporizable liquid are produced and introduced into the flow of carrier gas/vapor in a vaporization plenum with a sufficient flow of carrier gas/vapor to provide a curtain of carrier gas/vapor between substantially all of the fine particles of vaporizable liquid and the inner surface of the vaporization plenum.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: June 8, 2004
    Assignee: Pharmaceutical Systems, Inc.
    Inventors: Davoud Khorzad, Robert J. Thrash, Jimmy Fisher, Thomas F. Cullen
  • Publication number: 20030012689
    Abstract: Apparatus and method for testing one or more sterilization indicators (e.g., biological indicators or chemical indicators) or other articles by contacting them under controlled sterilization conditions with a flowing antimicrobial gas containing hydrogen peroxide vapor are disclosed. This invention also provides apparatus and method for testing sterilization processes that use a flowing antimicrobial gas containing hydrogen peroxide vapor under controlled sterilization conditions, or for testing materials for such processes under controlled sterilization conditions, or for testing both such processes and such materials under controlled sterilization conditions. There can be an essentially square-wave contact of the sterilization indicators or other articles with the antimicrobial gas (i.e.
    Type: Application
    Filed: July 9, 2001
    Publication date: January 16, 2003
    Applicant: PHARMACEUTICAL SYSTEMS, INC.
    Inventors: Ross A. Caputo, Robert R. Reich, Robert J. Thrash, Jimmy Fisher, Davoud Khorzad, Thomas F. Cullen
  • Publication number: 20030006375
    Abstract: Methods are disclosed for determining the monotonic functional relationship between (A) the integrated absorbance of spectral energy within a spectral region of interest of an analyte (i) that decomposes during the time experimental spectral data for determining the relationship are being obtained, or (ii) whose spectral data are pressure sensitive at pressures below a given pressure, or (iii) that decomposes during the time the spectral data are being obtained and whose spectral data are pressure sensitive and (B) the concentration of the analyte before decomposition commences. Methods are also disclosed for using the monotonic functional relationship to determine the concentration of the analyte in an unknown from the integrated absorbance of spectral energy within the spectral region of interest for the unknown.
    Type: Application
    Filed: July 9, 2001
    Publication date: January 9, 2003
    Applicant: PHARMACEUTICAL SYSTEMS, INC.
    Inventors: Robert J. Thrash, Thomas F. Cullen, Davoud Khorzad, Jimmy Fisher
  • Publication number: 20030007916
    Abstract: Apparatus and method for producing at high efficiency vaporization a precisely controllable, continuously adjustable gas-phase flow of a vaporizable liquid (e.g., hydrogen peroxide) in a carrier gas (e.g., air) are disclosed. The gas-phase product flow can be substantially continuous, low-temperature, unsaturated with respect to the vaporized vaporizable liquid, and of substantially constant vaporized vaporizable liquid concentration as a function of time. Fine particles of the vaporizable liquid are produced and introduced into the flow of carrier gas/vapor in a vaporization plenum with a sufficient flow of carrier gas/vapor to provide a curtain of carrier gas/vapor between substantially all of the fine particles of vaporizable liquid and the inner surface of the vaporization plenum.
    Type: Application
    Filed: July 9, 2001
    Publication date: January 9, 2003
    Applicant: PHARMACEUTICAL SYSTEMS, INC.
    Inventors: Davoud Khorzad, Robert J. Thrash, Jimmy Fisher, Thomas F. Cullen