Patents by Inventor Thomas F. Huff

Thomas F. Huff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CDNA clones coding for polypeptides exhibiting IGE binding factor activity
    Patent number: 4758511
    Abstract: Plasmid vectors are provided that carry complementary DNA (cDNA) clones coding for polypeptides exhibiting mammalian IgE binding factor activity. One of these clones contains an open reading frame consisting of 556 codons. The cDNA is derived from messenger RNA isolated from a rat/mouse T-cell hybridoma line. The cDNA was cloned by incorporation into a pcD plasmid vector. The plasmid vector also contains DNA segments from the SV40 virus, permitting expression of the cDNA to form a polypeptide having IgE potentiating activity after transfection into a mammalian host cell, such as monkey Cos7 cells.
    Type: Grant
    Filed: March 16, 1984
    Date of Patent: July 19, 1988
    Assignees: DNAX Research Institute of Molecular and Cellular Biology, Inc., The Johns Hopkins University
    Inventors: Christine L. Martens, Kevin W. Moore, Kimishige Ishizaka, Thomas F. Huff