Patents by Inventor Thomas F. Meyer

Thomas F. Meyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR REDUCING INDEX HOPPING
    Publication number: 20240093287
    Abstract: The present disclosure relates to compositions and methods for reducing the concentration of extendable free and buried primers relative to amplification product in a sample. The disclosed methods and compositions can be used to reduce or eliminate index hopping in a next generation sequencing (NGS) platform.
    Type: Application
    Filed: July 30, 2021
    Publication date: March 21, 2024
    Inventors: Keith Robison, Douglas G. Smith, Adam J. Meyer, Andrew J. Mitchell, Alex Plocik, Thomas F. Knight
  • CERVICAL CANCER ORGANOIDS
    Publication number: 20210355450
    Abstract: The present invention relates to a method for the production of a cervix epithelial cell organoid culture. By means of this method, an organoid culture of cervix epithelial cells, and a biobank comprising a plurality of different organoid cultures thereof may be generated. Further, a culture medium suitable for the long-term culture of epithelial stem cells is provided. Furthermore, the use of the organoid culture in the biobank for medical applications, e.g. in the field of diagnostics and therapy and in the fields of drug screening and immunotherapy is described.
    Type: Application
    Filed: October 11, 2019
    Publication date: November 18, 2021
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Rajendra Kumar GURUMURTHY, Cindrilla CHUMDURI, Thomas F. MEYER
  • OVARIAN CANCER ORGANOID CULTURE
    Publication number: 20210230555
    Abstract: The present invention relates to a method for the production of a culture, e.g. an organoid culture of ovarian cancer or cancer precursor cells, particularly of high grade serous ovarian carcinoma cells. By means of this method, an organoid culture of ovarian cancer or cancer precursor cells and a biobank comprising a plurality of different organoid cultures of ovarian cancer or cancer precursor cells may be generated. Further, a culture medium suitable for the long-term culture of ovarian cancer or cancer precursor cells is provided. Furthermore, use of the organoid culture and the biobank for medical applications, e.g. in the field of diagnostics, and therapy and in the field of drug screening is described.
    Type: Application
    Filed: February 22, 2019
    Publication date: July 29, 2021
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Thomas F. MEYER, Mirjana KESSLER
  • GENERATION, PROLIFERATION AND EXPANSION OF EPITHELIAL CELLS FROM PRIMARY TISSUE INTO MUCOSOID CULTURES
    Publication number: 20200362312
    Abstract: The invention relates to a method of culturing an epithelial cell on a solid surface.
    Type: Application
    Filed: January 18, 2019
    Publication date: November 19, 2020
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Francesco BOCCELLATO, Thomas F. MEYER
  • Influenza targets
    Patent number: 8933046
    Abstract: The present invention relates to a pharmaceutical composition comprising an inhibitor of influenza virus replication. Yet another aspect is a screening method for identification of new targets for the prevention, alleviation or/and treatment of influenza.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: January 13, 2015
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Nikolaus Machuy, Alexander Karlas, Thomas F. Meyer
  • PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CHLAMYDIAL INFECTION
    Publication number: 20130116302
    Abstract: Subject of the present invention is a pharmaceutical composition comprising at least one inhibitor of a microorganism selected from the family Chlamydiaceae.
    Type: Application
    Filed: March 11, 2011
    Publication date: May 9, 2013
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Rajendra Kumar Gurumurthy, Andre Paul Mauerer, Thomas F. Meyer, Marion Rother, Nikolaus Machuy, Erik Gonzalez Martinez
  • INFLUENZA TARGETS
    Publication number: 20130004502
    Abstract: The present invention relates to a pharmaceutical composition comprising an inhibitor of influenza virus replication. Yet another aspect is a screening method for identification of new targets for the prevention, alleviation or/and treatment of influenza.
    Type: Application
    Filed: December 22, 2010
    Publication date: January 3, 2013
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN e.V.
    Inventors: Nikolaus Machuy, Alexander Karlas, Thomas F. Meyer
  • METHOD FOR THE PREPARATION OF AN INFLUENZA VIRUS
    Publication number: 20120282674
    Abstract: The present invention relates to a method for the preparation of a pharmaceutical composition for the prevention or/and treatment of an influenza virus infection.
    Type: Application
    Filed: September 10, 2010
    Publication date: November 8, 2012
    Applicant: Maxplanck-Gesellschaft Zur Forderung der Wissenschaften E.V.
    Inventors: Nikolaus Machuy, Alexander Karlas, Thomas F. Meyer
  • Nucleic acid molecules encoding proteins which impart the adhesion of cells to human cells
    Patent number: 8114971
    Abstract: Described are nucleic acid molecules encoding proteins mediating the adhesion of bacteria of the genus Neisseria to human cells. Also described are the proteins encoded by these nucleic acid molecules and antibodies directed against them. Furthermore, pharmaceutical compositions, vaccines and diagnostic compositions containing the nucleic acid molecules, proteins and/or antibodies are described.
    Type: Grant
    Filed: May 3, 2007
    Date of Patent: February 14, 2012
    Assignee: Max-Planck Gesellschaft zur Forderung der Wissenschaften E.V.
    Inventors: Thomas F. Meyer, Thomas Rudel, Ina Scheuerpflug, Jurgen Maier, Sandra Eickernjager, Thomas Schwan, Eckhard Fischer
  • TARGETS FOR TREATMENT OF CHLAMYDIAL INFECTIONS
    Publication number: 20110245150
    Abstract: The present invention relates to a screening method for identification of a compound suitable for the prevention, treatment or/and diagnosis of an infection with Chlamydiaceae.
    Type: Application
    Filed: December 4, 2009
    Publication date: October 6, 2011
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Dagmar Heuer, Thomas F. Meyer, Anette Rejman Lipinski
  • INFLUENZA TARGETS
    Publication number: 20110150897
    Abstract: The present invention relates to pharmaceutical compositions comprising modulators of kinases, kinase binding polypeptides or/and an inhibitor for influenza virus replication for the prevention or/and treatment of influenza.
    Type: Application
    Filed: October 11, 2007
    Publication date: June 23, 2011
    Inventors: Thomas F. Meyer, Alexander Karlas, Nikolaus Machuy, Jan David Manntz, Elke Muller, Thomas Rudel
  • Nucleic acid molecules encoding proteins which impart the adhesion of Neisseria cells to human cells
    Publication number: 20080200665
    Abstract: Described are nucleic acid molecules encoding proteins mediating the adhesion of bacteria of the genus Neisseria to human cells. Also described are the proteins encoded by these nucleic acid molecules and antibodies directed against them. Furthermore, pharmaceutical compositions, vaccines and diagnostic compositions containing the nucleic acid molecules, proteins and/or antibodies are described.
    Type: Application
    Filed: May 3, 2007
    Publication date: August 21, 2008
    Inventors: Thomas F. Meyer, Thomas Rudel, Ina Scheuerpflug, Jurgen Maier, Sandra Eickernjager, Thomas Schwan, Eckhard Fischer
  • Export systems for recombinant proteins
    Patent number: 7129060
    Abstract: The present invention relates to vectors, host-vector combinations and processes for preparing stable fusion proteins consisting of a carrier protein and a passenger protein, where expression of the fusion proteins leads to exposure of the passenger domains on the surface of bacterial cells, especially Escherichia coli cells. If required, the passenger domains can be released into the medium by proteases, for example by selected host factors such as, for example, OmpT.
    Type: Grant
    Filed: March 15, 1996
    Date of Patent: October 31, 2006
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V
    Inventors: Jochen Maurer, Joachim Jose, Thomas F. Meyer
  • Identification of a new cytotoxic activity from the ink of
    Patent number: 7074889
    Abstract: The present invention relates to novel proteins having cytotoxic activity derived from the sea hare Aplysia.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: July 11, 2006
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften. E.V.
    Inventors: Daniel Butzke, Nikolaus Machuy, Thomas Rudel, Thomas F. Meyer
  • Identification of a new cytotoxic activity from the ink of aplysia punctata
    Publication number: 20040101940
    Abstract: The present invention relates to novel proteins having cytotoxic activity derived from the sea hare Aplysia.
    Type: Application
    Filed: September 23, 2003
    Publication date: May 27, 2004
    Inventors: Daniel Butzke, Nikolaus Machuy, Thomas Rudel, Thomas F Meyer
  • Method for identifying helicobacter antigens
    Publication number: 20030180330
    Abstract: The present invention relates to a method for characterizing or identifying proteins which are expressed by cultivated Helicobacter cells and which preferably react with human antisera. Thus, novel Helicobacter antigens are provided which are suitable as targets for the diagnostis, prevention or treatment of Helicobacter infections.
    Type: Application
    Filed: April 29, 2003
    Publication date: September 25, 2003
    Inventors: Thomas F Meyer, Peter Jungblut, Dirk Baumann, Anton Aebischer, Gaby Haas, Ursula Zimny-Arndt, Stephanie Lamer, Galip Karaali, Nicolas Sabarth, Meike Wendland
  • Nucleic acid molecules encoding proteins which impart the adhesion of neisseria cells to human cells
    Patent number: 6617128
    Abstract: Described are nucleic acid molecules encoding proteins mediating the adhesion of bacteria of the genus Neisseria to human cells. Also described are the proteins encoded by these nucleic acid molecules and antibodies directed against them. Furthermore, pharmaceutical compositions, vaccines and diagnostic compositions containing the nucleic acid molecules, proteins and/or antibodies are described.
    Type: Grant
    Filed: June 8, 1998
    Date of Patent: September 9, 2003
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Thomas F. Meyer, Thomas Rudel, Ina Scheuerpflug, Jurgen Maier, Sandra Eickernjager, Thomas Schwan, Eckhard Fischer
  • Adherence gene from Helicobacter pylori and polypeptide coded thereby
    Patent number: 6593461
    Abstract: The present invention concerns an adherence gene from Helicobacter pylori, a polypeptide coded thereby and antibodies against the polypeptide.
    Type: Grant
    Filed: December 10, 1997
    Date of Patent: July 15, 2003
    Assignee: Max-Planck-Gesellschaft zur Föderung der Wissenscaften e.v.
    Inventors: Rainer Haas, Stefan Odenbreit, Thomas F. Meyer, André Blum, Irène Corthésy-Theulaz
  • Helicobacter antigens and corresponding DNA fragments
    Publication number: 20030069404
    Abstract: The invention provides Helicobacter polypeptides that can be used in vaccination methods for preventing or treating Helicobacter infection, and polynucleotides that encode these polypeptides.
    Type: Application
    Filed: November 5, 2001
    Publication date: April 10, 2003
    Inventors: Rainer Haas, Harold Kleanthous, Thomas F. Meyer, Stefan Odenbreit, Amal A. Al-Garawi, Charles A. Miller
  • Helicobacter pylori live vaccine
    Publication number: 20020161192
    Abstract: The present invention relates to novel recombinant live vaccines, which provide protective immunity against an infection by Helicobacter pylori and a method of screening H. pylori antigens for optimized vaccines.
    Type: Application
    Filed: October 15, 2001
    Publication date: October 31, 2002
    Inventors: Thomas F. Meyer, Rainer Haas, Yan Zhengxin, Oscar Gomez-Duarte, Bernadette Lucas, Jochen Maurer, Carol Patrice Gibbs, Claus Tobias Lattemann