Patents by Inventor Thomas Flaig

Thomas Flaig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multifunctional nanomaterials for the treatment of cancer
    Patent number: 10052393
    Abstract: The invention relates to a multifunctional nanomaterial comprising a nanorod comprising 1) a noble metal, wherein the nanorod exhibits surface plasmon resonance absorption in the near-infrared spectrum; 2) an up-conversion phosphor that absorbs infrared light and emits visible luminescence; and optionally 3) a biomolecule targeting moiety. The invention further relates to methods of detecting and treating cancer using the multifunctional nanomaterials of the invention.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: August 21, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Wounjhang Park, Thomas Flaig, Xiaoping Yang, Lih-Jen Shih Su, Kazunori Emoto
  • Compositions and methods for treating bladder cancer
    Patent number: 9321820
    Abstract: The present invention provides methods and compositions for treating bladder cancer. In particular, the present invention provides a fusion protein comprising a toxin moiety that is linked to an epithelial growth factor (EGF) moiety. The toxin moiety and the EGF moiety can be linked optionally via a linker. Typically, the fusion protein is administered intravesically into the cancerous bladder.
    Type: Grant
    Filed: October 14, 2010
    Date of Patent: April 26, 2016
    Assignees: The Regents of the University of Colorado, Scott & White Healthcare
    Inventors: Thomas Flaig, Arthur E. Frankel, Andrew Thorburn, Michael L. Glode
  • MULTIFUNCTIONAL NANOMATERIALS FOR THE TREATMENT OF CANCER
    Publication number: 20140378831
    Abstract: The invention relates to a multifunctional nanomaterial comprising a nanorod comprising 1) a noble metal, wherein the nanorod exhibits surface plasmon resonance absorption in the near-infrared spectrum; 2) an up-conversion phosphor that absorbs infrared light and emits visible luminescence; and optionally 3) a biomolecule targeting moiety. The invention further relates to methods of detecting and treating cancer using the multifunctional nanomaterials of the invention.
    Type: Application
    Filed: January 25, 2013
    Publication date: December 25, 2014
    Applicant: The Regents of the University of Colorado, a body corporate
    Inventors: Wounjhang Park, Thomas Flaig, Xiaping Yang, Lih-Jen Shih Su, Kazunori Emoto
  • Compositions and Methods for Treating Bladder Cancer
    Publication number: 20120232010
    Abstract: The present invention provides methods and compositions for treating bladder cancer. In particular, the present invention provides a fusion protein comprising a toxin moiety that is linked to an epithelial growth factor (EGF) moiety. The toxin moiety and the EGF moiety can be linked optionally via a linker. Typically, the fusion protein is administered intravesically into the cancerous bladder.
    Type: Application
    Filed: October 14, 2010
    Publication date: September 13, 2012
    Applicant: The Regents of the University of Colorado, a body corporate
    Inventors: Thomas Flaig, Arthur E. Frankel, Andrew Thorburn, L.Michael Glode, Jung Hee Woo, David Neville
  • Mechanical acceleration sensor
    Patent number: 6610940
    Abstract: A switch includes a deflectable inertial mass that responds to acceleration. The inertial mass is for activating a switching system. The inertial mass is suspended on two parallel, elastically deflectable support arms having a first, firmly anchored end and a second, movable end to which the inertial mass is attached.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: August 26, 2003
    Assignee: TRW Automotive Electronics & Components GmbH & Co. KG
    Inventors: Thomas Flaig, Robert Skofljanec
  • Mechanical acceleration sensor
    Publication number: 20020084176
    Abstract: A switch comprising a deflectable inertial mass that responds to acceleration, by means of which a switching system can be actuated, characterized in that the inertial mass is suspended on two parallel, elastically deflectable support arms having a first, firmly anchored end and a second, movable end to which the inertial mass is attached.
    Type: Application
    Filed: December 17, 2001
    Publication date: July 4, 2002
    Applicant: TRW Automotive Electronics & Components GmbH & Co. KG
    Inventors: Thomas Flaig, Robert Skofljanec