Abstract: In accordance with at least one exemplary embodiment, a syringe device, method and system for delivering a therapeutic amount of ozone are disclosed. A sterility case can enclose a syringe portion and can maintain sterility while the syringe device is interfaced to an ozone generator. A valvably-controlled fluid channel can extend from the barrel of the syringe through the case. Conducting elements can be attached to the case and can breach the case. The conductive elements can be connected to electrodes. The electrodes can be attached to the syringe. The syringe portion can be filled with oxygen gas via the valvably-controlled fluid channel. An electric current can be provided to the conductive elements from an ozone generator resulting in a corona discharge from at least one electrode. A therapeutic amount of ozone gas can be produced from the oxygen gas and the syringe delivered into the sterile field without compromise.

Abstract: In accordance with at least one exemplary embodiment, a syringe device, a method and a system for delivering a therapeutic amount of ozone are disclosed. A sterility case can enclose a syringe portion and can maintain sterility while the syringe device is interfaced to an ozone generator. A valvably-controlled fluid channel can extend from a barrel of the syringe portion through the case. Conducting elements can be attached to the case and can breach the case. The conducting elements can be connected to electrodes. The electrodes can be attached to the syringe portion. The syringe portion can be filled with oxygen gas via the valvably-controlled fluid channel. An electric current can be provided to the conducting elements from the ozone generator resulting in a corona discharge from at least one of the electrodes. A therapeutic amount of ozone gas can be produced from the oxygen gas and the syringe portion delivered into a sterile field without compromise.

Abstract: An apparatus for determining the location of a radio-opaque marker embedded in an excised specimen includes a radio-opaque marker including an energy beacon that can be embedded in the specimen, an energy beacon controller, at least three detectors, a signal processing component, and a display device. An associated method is disclosed. A method for evaluating a radiographically labeled excised specimen involves determining the location of a radio-opaque marker embedded in the excised specimen, anatomically sectioning the excised specimen, macro-optically segmenting the sectioned specimen into an adipose tissue component, a fibrous tissue component, and an epithelial tissue component, and microscopically examining at least one of the tissue components. An associated apparatus is disclosed.

Abstract: In accordance with at least one exemplary embodiment, a syringe device, method and system for delivering a therapeutic amount of ozone are disclosed. A sterility case can enclose a syringe portion and can maintain sterility while the syringe device is interfaced to an ozone generator. A valvably-controlled fluid channel can extend from the barrel of the syringe through the case. Conducting elements can be attached to the case and can breach the case. The conductive elements can be connected to electrodes. The electrodes can be attached to the syringe. The syringe portion can be filled with oxygen gas via the valvably-controlled fluid channel. An electric current can be provided to the conductive elements from an ozone generator resulting in a corona discharge from at least one electrode. A therapeutic amount of ozone gas can be produced from the oxygen gas and the syringe delivered into the sterile field without compromise.

Abstract: In accordance with at least one exemplary embodiment, a syringe device, a method and a system for delivering a therapeutic amount of ozone are disclosed. A sterility case can enclose a syringe portion and can maintain sterility while the syringe device is interfaced to an ozone generator. A valvably-controlled fluid channel can extend from a barrel of the syringe portion through the case. Conducting elements can be attached to the case and can breach the case. The conductive elements can be connected to electrodes. The electrodes can be attached to the syringe portion. The syringe portion can be filled with oxygen gas via the valvably-controlled fluid channel. An electric current can be provided to the conductive elements from the ozone generator resulting in a corona discharge from at least one of the electrodes. The therapeutic amount of ozone can be produced from the oxygen gas and the syringe portion delivered into a sterile field without compromise.

Abstract: In accordance with at least one exemplary embodiment, a syringe, method and system for delivering a therapeutic amount of ozone are disclosed. An exemplary syringe can have a gas chamber and one or more electrodes. A portion of at least one electrode can be within the gas chamber. Alternatively, singularly or in conjunction, one or both electrodes can be attached to the outside of an exemplary syringe. One or more electrical contact points can be outside the gas chamber. Each electrical contact point can be connected to an electrode. Oxygen gas can provided within the gas chamber of the exemplary syringe. A medical ozone generator can be connected to the syringe via the electrical contact points. Corona discharge can be effectuated via the electrodes, which can result in an amount of ozone gas can being produced from the oxygen gas.

Abstract: In accordance with at least one exemplary embodiment, a syringe, method and system for delivering a therapeutic amount of ozone are disclosed. An exemplary syringe can have a gas chamber and one or more electrodes. A portion of at least one electrode can be within the gas chamber. Alternatively, singularly or in conjunction, one or both electrodes can be attached to the outside of an exemplary syringe. One or more electrical contact points can be outside the gas chamber. Each electrical contact point can be connected to an electrode. Oxygen gas can provided within the gas chamber of the exemplary syringe. A medical ozone generator can be connected to the syringe via the electrical contact points. Corona discharge can be effectuated via the electrodes, which can result in an amount of ozone gas can being produced from the oxygen gas.

Abstract: An apparatus for determining the location of a radio-opaque marker embedded in an excised specimen includes a radio-opaque marker including an energy beacon that can be embedded in the specimen, an energy beacon controller, at least three detectors, a signal processing component, and a display device. An associated method is disclosed. A method for evaluating a radiographically labeled excised specimen involves determining the location of a radio-opaque marker embedded in the excised specimen, anatomically sectioning the excised specimen, macro-optically segmenting the sectioned specimen into an adipose tissue component, a fibrous tissue component, and an epithelial tissue component, and microscopically examining at least one of the tissue components. An associated apparatus is disclosed.

Abstract: In accordance with at least one exemplary embodiment, a syringe, method and system for delivering a therapeutic amount of ozone are disclosed. An exemplary syringe can have a gas chamber and one or more electrodes. A portion of at least one electrode can be within the gas chamber. Alternatively, singularly or in conjunction, one or both electrodes can be attached to the outside of an exemplary syringe. One or more electrical contact points can be outside the gas chamber. Each electrical contact point can be connected to an electrode. Oxygen gas can provided within the gas chamber of the exemplary syringe. A medical ozone generator can be connected to the syringe via the electrical contact points. Corona discharge can be effectuated via the electrodes, which can result in an amount of ozone gas can being produced from the oxygen gas.

Abstract: In accordance with at least one exemplary embodiment, a syringe, method and system for delivering a therapeutic amount of ozone are disclosed. An exemplary syringe can have a gas chamber and one or more electrodes. A portion of at least one electrode can be within the gas chamber. Alternatively, singularly or in conjunction, one or both electrodes can be attached to the outside of an exemplary syringe. One or more electrical contact points can be outside the gas chamber. Each electrical contact point can be connected to an electrode. Oxygen gas can provided within the gas chamber of the exemplary syringe. A medical ozone generator can be connected to the syringe via the electrical contact points. Corona discharge can be effectuated via the electrodes, which can result in an amount of ozone gas can being produced from the oxygen gas.

Abstract: In accordance with at least one exemplary embodiment, a syringe, method and system for delivering a therapeutic amount of ozone are disclosed. An exemplary syringe can have a gas chamber and one or more electrodes. A portion of at least one electrode can be within the gas chamber. Alternatively, singularly or in conjunction, one or both electrodes can be attached to the outside of an exemplary syringe. One or more electrical contact points can be outside the gas chamber. Each electrical contact point can be connected to an electrode. Oxygen gas can provided within the gas chamber of the exemplary syringe. A medical ozone generator can be connected to the syringe via the electrical contact points. Corona discharge can be effectuated via the electrodes, which can result in an amount of ozone gas can being produced from the oxygen gas.

Abstract: A statistical and functional correlation strategy to identify changes in cellular pathways specifically linked to impaired cognitive function with aging. Analyses using the strategy identified multiple groups of genes expressed in the hippocampi of mammals, where the genes were expressed at different levels for several ages. The aging changes in expression began before mid-life. Many of the genes were involved in specific neuronal and glial pathways with previously unrecognized relationships to aging and/or cognitive decline. These identified genes and the proteins they encode can be used as novel biomarkers of brain aging and as targets for developing treatment methods against age-related cognitive decline, Alzheimer's Disease and Parkinson's Disease.

Abstract: A statistical and functional correlation strategy to identify changes in cellular pathways specifically linked to impaired cognitive function with aging. Analyses using the strategy identified multiple groups of genes expressed in the hippocampi of mammals, where the genes were expressed at different levels for several ages. The aging changes in expression began before mid-life. Many of the genes were involved in specific neuronal and glial pathways with previously unrecognized relationships to aging and/or cognitive decline. These identified genes and the proteins they encode can be used as novel biomarkers of brain aging and as targets for developing treatment methods against age-related cognitive decline, Alzheimer's Disease and Parkinson's Disease.

Abstract: Apparatus, method and system for delivering a sterile unit dose of ozone that may include concentrating oxygen from air, which can include pressurizing at least one zeolite chamber having at least one zeolite material where the at least one zeolite material selectively adsorbs a substantial amount of nitrogen and not a substantial amount of oxygen. An oxygen-ozone cell may be filled with substantially concentrated oxygen from the at least one zeolite chamber. The oxygen-ozone cell may then be sequestered. The oxygen-ozone cell may be removed and may be engaged with an ozone conversion unit. The ozone conversion unit may charge the substantially concentrated oxygen generating a predetermined concentration of ozone. The oxygen-ozone cell may be disengaged from the ozone conversion unit.

Abstract: An optical probe has multiple side-firing optical fibers which terminate in a linearly staggered fashion. A central fiber can be used as well. In diagnostic techniques, one fiber can be used as an emitter, while the others are used as receivers, or various fibers can be used as emitters and receivers at different times to form a map of the area. In therapeutic techniques, the treatment light can be emitted from the fibers in parallel or in sequence, and the fluence can be independently adjusted for each of the fibers.

Abstract: In accordance with at least one exemplary embodiment, a syringe device, method and system for delivering a therapeutic amount of ozone are disclosed. A sterility case can enclose a syringe portion and can maintain sterility while the syringe device is interfaced to an ozone generator. A valvably-controlled fluid channel can extend from the barrel of the syringe through the case. Conducting elements can be attached to the case and can breach the case. The conductive elements can be connected to electrodes. The electrodes can be attached to the syringe. The syringe portion can be filled with oxygen gas via the valvably-controlled fluid channel. An electric current can be provided to the conductive elements from an ozone generator resulting in a corona discharge from at least one electrode. A therapeutic amount of ozone gas can be produced from the oxygen gas and the syringe delivered into the sterile field without compromise.

Abstract: In accordance with at least one exemplary embodiment, a syringe, method and system for delivering a therapeutic amount of ozone are disclosed. An exemplary syringe can have a gas chamber and one or more electrodes. A portion of at least one electrode can be within the gas chamber. Alternatively, singularly or in conjunction, one or both electrodes can be attached to the outside of an exemplary syringe. One or more electrical contact points can be outside the gas chamber. Each electrical contact point can be connected to an electrode. Oxygen gas can provided within the gas chamber of the exemplary syringe. A medical ozone generator can be connected to the syringe via the electrical contact points. Corona discharge can be effectuated via the electrodes, which can result in an amount of ozone gas can being produced from the oxygen gas.

Abstract: In accordance with the present invention, methods are provided for treating a patient through the use of ultraviolet light activated gene therapy. Embodiments of the present invention include methods for the utilization of light activated gene therapy to repair and/or rebuild damaged cartilage by introducing a desired gene into a patient's tissue.

Abstract: In accordance with the present invention, methods are provided for treating a patient through the use of ultraviolet light activated gene therapy. Embodiments of the present invention include methods for the utilization of light activated gene therapy to repair and/or rebuild damaged cartilage by introducing a desired gene into a patient's tissue.

Abstract: Apparatus, method and system for delivering a sterile unit dose of ozone that may include concentrating oxygen from air, which can include pressurizing at least one zeolite chamber having at least one zeolite material where the at least one zeolite material selectively adsorbs a substantial amount of nitrogen and not a substantial amount of oxygen. An oxygen-ozone cell may be filled with substantially concentrated oxygen from the at least one zeolite chamber. The oxygen-ozone cell may then be sequestered. The oxygen-ozone cell may be removed and may be engaged with an ozone conversion unit. The ozone conversion unit may charge the substantially concentrated oxygen generating a predetermined concentration of ozone. The oxygen-ozone cell may be disengaged from the ozone conversion unit.