Abstract: A three-dimensional structure is formed when layers of a material are deposited onto a substrate and scanned with a high energy beam to at least partially melt each layer of the material. Upon scanning the layers at predetermined locations at least a first segment overlapping a second segment and underlapping a third segment is formed.

Abstract: A PAP system includes a PAP device to generate a supply of pressurized air, a patient interface adapted to form a seal with the patient's face, air delivery tubing to interconnect the patient interface and the PAP device, and a cover that substantially encloses at least a portion of the PAP device and a portion of the air delivery tubing. The cover allows the PAP device to be carried by and/or supported on the patient's head.

Abstract: This disclosure relates to a bootstrapped switching circuit. Example embodiments include a bootstrapped switching circuit (100) comprising: a positive output node (109+); a negative output node (109?); a first input node (106a) configured to receive a first input voltage (Vin1); a second input node (106b) configured to receive a second input voltage (Vin2). First, second third and fourth switches (101-104) are coupled between the input and output nodes (106a, 106b, 109+, 109?). A first negative bootstrapped level shifter (107a) and a first positive bootstrapped level shifter (107b) coupled between the first input node (106a) and a first clock signal circuit (110a) provide control signals to the first and second switches (101, 102). A second negative bootstrapped level shifter (108a) and a second positive bootstrapped level shifter (108b) coupled between the second input node (106b) and a second ground referenced supply line (110b) provide control signals to the third and fourth switches (103, 104).

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: Disclosed herein is an implant. The implant can include a body and a plurality of fixation members. The body can define an articular surface and a bone engaging surface opposite the articular surface. The bone engaging surface can define a groove that separates a first section of the bone engaging surface from a second section of the bone engaging surface. The plurality of fixation members can extend from the bone engaging surface.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: A document is obtained that include natural language text and a set of conditions are extracted from the document. In at least one embodiment, the set of conditions is extracted using a machine learning model trained on other natural language text. A validation process is performed to result in a validated set of conditions and a machine-readable data structure is generated to indicate one or more conditions of the validated set of conditions expressed within the document.

Abstract: The present invention relates to the treatment of subjects having CD20-positive cell proliferative disorders (e.g., B cell proliferative disorders, such as non-Hodgkin's lymphomas). More specifically, the invention pertains to the treatment of subjects having a CD20-positive cell proliferative disorder (e.g., B cell proliferative disorder) by administering a combination of an anti-CD20/anti-CD3 bispecific antibody and an anti-CD79b antibody drug conjugate.

Abstract: A customer application renders a customer graphical user interface including a plurality of items for sale at a store and generates a customer order in response to input received from the customer. The customer order includes a plurality of ordered items for picking in the store. The customer application is configured to generate an order modification interface configured to receive at least one of addition modifications, deletion modifications, and substitution modifications. A computing system is configured to determine whether the customer order is eligible to be modified by the customer based on satisfaction of one or more modification eligibility conditions and send an eligibility determination to the customer device that indicates whether the customer order is eligible to be modified. The customer application is configured to receive customer input in the order modification interface that modifies the customer order when the customer order is eligible to be modified.

Abstract: The systems and methods may use one or more artificial intelligence models that predict an effect of a predicted event on a current state of the system. For example, the model may predict how a rate of change in time-series data may be altered throughout the first time period based on the predicted event. However, as noted above, correctly predicting the occurrence of outlier events (e.g., the predicted event), and in particular characteristics about the outlier events (e.g., when an outlier may occur, what may be a source of the outlier, what rate of change the outlier may cause, etc.), in data-sparse environments and based on time-series data presents a technical challenge.

Abstract: Systems and methods are described herein for novel uses and/or improvements to data aggregation related to artificial intelligence applications, specifically applications related to aggregating time-series data. As one example, systems and methods are described herein for predicting effects when aggregating time-series data and modifying the one or more data streams used to populate a model profile and/or feed an artificial intelligence application with the time-series data.

Abstract: Systems, methods, and products are configured for receiving a request from a first electronic device to connect to a first network and determining an electronic communication protocol of the first electronic device. A database can be queried to identify a communication protocol restriction corresponding to the electronic communication protocol of the first electronic device and connecting the first electronic device to a subnetwork. Continuous monitoring of data traffic can be performed to identify data packets transmitted from the first electronic device to a second electronic device can be performed, and, upon identifying at least one data packet transmitted from the first electronic device to the second electronic device, the connection between the first electronic device and the second electronic device can be terminated.

Abstract: Systems and methods are described herein for novel uses and/or improvements to data aggregation related to artificial intelligence applications, specifically applications related to aggregating time-series data. As one example, systems and methods are described herein for predicting effects when aggregating time-series data and modifying the one or more data streams used to populate a model profile and/or feed an artificial intelligence application with the time-series data.