Patents by Inventor Thomas Frederick Bishop

Thomas Frederick Bishop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for reducing dephasing during cluster DNA sequencing
    Patent number: 10329615
    Abstract: A method for nucleic acid sequencing, comprising: exposing a plurality of clusters of a plurality of template polynucleotide strands to a series of flows of a plurality of nucleotide or oligonucleotide solutions, wherein the nucleotide solutions or oligonucleotide solutions are flowed in an order of flow which is not a continuous repeat of an ordering of a single flow of each of the nucleotide solutions or oligonucleotide solutions; and obtaining a fluorescence signal indicative of which, if any, nucleotide species or oligonucleotide species incorporated to determine a predicted sequence of nucleotides corresponding to the template polynucleotide strands. This method enables dephased amplicons to return in-phase.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: June 25, 2019
    Inventor: Thomas Frederick Bishop
  • Method for reducing dephasing during cluster DNA sequencing
    Publication number: 20170016064
    Abstract: A method for nucleic acid sequencing, comprising: exposing a plurality of clusters of a plurality of template polynucleotide strands to a series of flows of a plurality of nucleotide or oligonucleotide solutions, wherein the nucleotide solutions or oligonucleotide solutions are flowed in an order of flow which is not a continuous repeat of an ordering of a single flow of each of the nucleotide solutions or oligonucleotide solutions; and obtaining a fluorescence signal indicative of which, if any, nucleotide species or oligonucleotide species incorporated to determine a predicted sequence of nucleotides corresponding to the template polynucleotide strands. This method enables dephased amplicons to return in-phase.
    Type: Application
    Filed: July 8, 2016
    Publication date: January 19, 2017
    Inventor: Thomas Frederick Bishop