Patents by Inventor Thomas G. Back

Thomas G. Back has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleoside-Based Anti-Bacterial and Anti-Protozoan Drugs
    Publication number: 20180037601
    Abstract: The present invention is directed to purine nucleoside analogs of the general formula I or salts and pharmaceutical compositions comprising such compounds and salts, which are useful as anti-protozoan agents. The invention is also directed to methods for treating a protozoan infection in a mammal and use of the compounds for inhibiting the growth of protozoa.
    Type: Application
    Filed: October 20, 2017
    Publication date: February 8, 2018
    Inventors: Thomas G. BACK, Floyd F. SNYDER
  • Ryanodine receptor inhibitors and methods relating thereto
    Patent number: 8703804
    Abstract: The present invention provides novel ryanodine receptor type 2 (RyR2) inhibitors and methods of their use in the treatment of cardiac conditions. In general, the RyR2 inhibitors of the present invention assist in the normalization of intracellular calcium homeostasis. In certain embodiments, the RyR2 inhibitors are store-overload-induced Ca2+ release (SOICR) inhibitors that minimally inhibit or do not inhibit Ca2+-induced Ca2+ release (CICR), thereby providing beneficial effects in cardiac therapy.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: April 22, 2014
    Assignee: UTI Limited Partnership
    Inventors: S. R. Wayne Chen, Thomas G. Back, Dawei Jiang, Kannan Vembaiyan
  • Glutathione peroxidase mimetics and uses thereof
    Patent number: 7923442
    Abstract: This invention relates to novel organoselenium and tellurium compounds, processes of producing the same and methods of use thereof. The compounds function as mimetics for the catalyst selenoenzyme glutathione peroxidase, which protects cells from oxidative stress.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: April 12, 2011
    Assignee: UTI Limited Partnership
    Inventors: Dusan Kuzma, Thomas G. Back, Noah Berkowitz
  • Non-steroidal mimetics of brassinolide
    Patent number: 6667278
    Abstract: Non steroidal mimetics or analogues of brassinosteroids such as brassinolide include two bicyclic subunits each having a vicinal diol group and a polar unit and linked by a linking moiety such that the vicinal diol groups and polar unit are closely superimposable on corresponding functional groups in the brassinosteroid.
    Type: Grant
    Filed: December 5, 2001
    Date of Patent: December 23, 2003
    Assignee: University Technologies International Inc.
    Inventors: Thomas G. Back, Richard P. Pharis, Denise L. Andersen, Gabriel Sung
  • Non-steroidal mimetics of brassinolide
    Publication number: 20020115570
    Abstract: Non steroidal mimetics or analogues of brassinosteroids such as brassinolide include two bicyclic subunits each having a vicinal diol group and a polar unit and linked by a linking moiety such that the vicinal diol groups and polar unit are closely superimposable on corresponding functional groups in the brassinosteroid.
    Type: Application
    Filed: December 5, 2001
    Publication date: August 22, 2002
    Inventors: Thomas G. Back, Richard P. Pharis, Denise L. Andersen, Gabriel Sung
  • Brassinosteroid analogs useful as plant growth regulators
    Patent number: 6239073
    Abstract: Disclosed are compositions and methods for promoting plant growth. The compounds are cyclopropyl-, cyclobutyl-, and cyclopentyl-substituted brassinosteroids having high growth promoting ability. They may be used alone or in combination with other plant growth regulating agents.
    Type: Grant
    Filed: November 4, 1999
    Date of Patent: May 29, 2001
    Assignee: Exelixis Plant Sciences, Inc.
    Inventors: Thomas G. Back, Richard P. Pharis, Suanne K. Nakajima
  • Brassinosteroid analogs useful as plant growth regulators
    Patent number: 6063731
    Abstract: Disclosed are compositions and methods for promoting plant growth. The compounds are cyclopropyl- and cyclobutyl-substituted brassinosteroids having high growth promoting ability. They may be used alone or in combination with other plant growth regulating agents.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: May 16, 2000
    Assignee: Agritope, Inc.
    Inventors: Thomas G. Back, Richard P. Pharis, Suanne K. Nakajima