Patents by Inventor Thomas G. Cullen
Thomas G. Cullen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7683070Abstract: It has now been found that certain novel N-(substituted aryl)-4-(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is C or CH; and B, D, E, R, R1, R2, R3, R4, R5, R6, R7 and R8 are fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.Type: GrantFiled: October 17, 2007Date of Patent: March 23, 2010Assignee: FMC CorporationInventors: Ping Ding, Robert N. Henrie, II, Daniel H. Cohen, John W. Lyga, David S. Rosen, George Theodoridis, Qun Zhang, Walter H. Yeager, Stephen F. Donovan, Stephen Shunxiang Zhang, Inna Shulman, Seong Jae Yu, Guozhi Wang, Y. Larry Zhang, Ariamala Gopalsamy, Dennis L. Warkentin, Paul E. Rensner, Ian R. Silverman, Thomas G. Cullen
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Patent number: 7365082Abstract: It has now been found that certain novel N-(substituted aryl)-4-(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is CH or N; and B, D, E, R, R1, R2, R3, R4, R5, R6, R7 and R8 are fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.Type: GrantFiled: December 8, 2003Date of Patent: April 29, 2008Assignee: Bayer CropScience AGInventors: Ping Ding, Robert N. Henrie, II, Daniel H. Cohen, John W. Lyga, David S. Rosen, George Theodoridis, Qun Zhang, Walter H. Yeager, Stephen F. Donovan, Steven Shunxiang Zhang, Inna Shulman, Seong Jae Yu, Guozhi Wang, Y. Larry Zhang, Ariamala Gopalsamy, Dennis L. Warkentin, Paul E. Rensner, Ian R. Silverman, Thomas G. Cullen
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Patent number: 7300946Abstract: It has now been found that certain novel N-(substituted aryl)-4(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is C or CH; and B, D, E, R, R1, R2, R3, R4, R5, R6, R7 and R8 are fully described herein.Type: GrantFiled: December 8, 2003Date of Patent: November 27, 2007Assignee: Bayer CropScience AGInventors: Ping Ding, Robert N. Henrie, II, Daniel H. Cohen, John W. Lyga, David S. Rosen, George Theodoridis, Qun Zhang, Walter H. Yeager, Stephen F. Donovan, Steven Shunxiang Zhang, Inna Shulman, Seong Jae Yu, Guozhi Wang, Y. Larry Zhang, Ariamala Gopalsamy, Dennis L. Warkentin, Paul E. Rensner, Ian R. Silverman, Thomas G. Cullen
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Patent number: 7247756Abstract: Compounds of formula I: wherein A, B, D, and R are as defined herein and their agriculturally acceptable salts are disclosed as effective insecticides. In addition, compositions comprising an insecticidally effective amount of a compound of Formula I in admixture with at least one agriculturally acceptable extender or adjuvant and methods of controlling insects comprising applying the compositions to locus on crops where control is desired are disclosed.Type: GrantFiled: January 29, 2003Date of Patent: July 24, 2007Assignee: Bayer CropScience AGInventors: George Theodoridis, Edward Barron, Daniel H. Cohen, Ellen M. Crawford, Thomas G. Cullen, Hongyan Qi, Elizabeth Rowley, Syed F. Ali, Walter H. Yeager, Christina B. Duggan
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Patent number: 6753429Abstract: Compounds of formula I: wherein A, B, D, and R are as defined herein and their agriculturally acceptable salts are disclosed as effective insecticides. In addition, compositions comprising an insecticidally effective amount of a compound of Formula I in admixture with at least one agriculturally acceptable extender or adjuvant and methods of controlling insects comprising applying said compositions to locus on crops where control is desired are disclosed. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims (see 37 C.F.R. 1.72(b)).Type: GrantFiled: August 29, 2001Date of Patent: June 22, 2004Assignee: FMC CorporationInventors: George Theodoridis, Edward Barron, Daniel H. Cohen, Ellen M. Crawford, Thomas G. Cullen, Hongyan Qi, Elizabeth Rowley, Syed F. Ali, Walter H. Yeager, Christina B. Duggan
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Publication number: 20030207894Abstract: Compounds of formula I: 1Type: ApplicationFiled: January 29, 2003Publication date: November 6, 2003Inventors: George Theodoridis, Edward Barron, Daniel H. Cohen, Ellen M. Crawford, Thomas G. Cullen, Hongyan Qi, Elizabeth Rowley, Syed F. Ali, Walter H. Yeager, Christina B. Duggan
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Publication number: 20020183342Abstract: Compounds of formula I: 1Type: ApplicationFiled: August 29, 2001Publication date: December 5, 2002Inventors: George Theodoridis, Edward Barron, Daniel H. Cohen, Ellen M. Crawford, Thomas G. Cullen, Hongyan Qi, Elizabeth Rowley, Syed F. Ali, Walter H. Yeager, Christina B. Duggan
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Patent number: 6214845Abstract: Compounds of the following structure, the corresponding N-oxides and agriculturally acceptable salts, are disclosed as effective insecticides: in which U is —(CH2)n—; Q is hydroxy; R is in which V, W, Y, and Z are each hydrogen; X is a five- or six-membered heterocycle; optionally substituted with halogen, cyano, alkyl, haloalkyl, alkoxy, haloalkoxy, alkoxyalkyl, haloalkoxyalkyl, or aminocarbonyl; and the heterocycle is optionally connected to the phenyl ring through a —O—, —S—, —(CH2)p, —C(O)—, or —O—(CR3R4)q linkage; R1 and R2 are independently selected from phenyl or pyridyl substituted with haloalkyl or haloalkoxy; R3 and R4 are independently selected from hydrogen and methyl; n and p are independently 1, 2, or 3; and q is 1 or 2; with the proviso that at least one of R1 and R2 is substituted in the para position; no more than two of R3 and R4 are methyl; each aliphatic moiety contains not more tType: GrantFiled: September 2, 1999Date of Patent: April 10, 2001Assignee: FMC CorporationInventors: Ian R. Silverman, Daniel H. Cohen, John W. Lyga, Steven W. Szczepanski, Syed F. Ali, Thomas G. Cullen, Robert N. Henrie, II, Clinton J. Peake
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Patent number: 6184234Abstract: Compounds of the following structure, the corresponding N-oxides and agriculturally acceptable salts thereof, are disclosed as effective insecticides: wherein U is —(CH2)n—; Q is hydroxy; and R is: and wherein V, W, Y, and Z are each hydrogen; X is a five- or six-membered heterocycle; optionally substituted with bromine, chlorine, fluorine, cyano, alkyl, haloalkyl, alkoxy, haloalkoxy, alkoxyalkyl, haloalkoxyalkyl, or aminocarbonyl; and the heterocycle is optionally connected to the phenyl ring through a —O—, —S—, —(CH2)p, —C(O)—, or —O—(CR3R4)q linkage; R1 and R2 are independently selected from phenyl or pyridyl substituted with pentahalothio, haloalkylthio, haloalkylsulfinyl, or haloalkylsulfonyl; phenyl substituted with —OC(M)2O—, where M is bromine, chorine or fluorine, to provide a dihalobenzodioxolyl fused ring; or pyridyl substituted with —OC(M)2O— to provide a dihalodioxolType: GrantFiled: October 7, 1999Date of Patent: February 6, 2001Assignee: FMC CorporationInventors: Ian R. Silverman, Daniel H. Cohen, John W. Lyga, Steven W. Szczepanski, Syed F. Ali, Thomas G. Cullen, Robert N. Henrie, II, Clinton J. Peake
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Patent number: 6030987Abstract: Compounds of structure (I) ##STR1## the corresponding N-oxides and agriculturally acceptable salts are disclosed as effective insecticides. In said formula, U is --(CH.sub.2)n--; Q is hydroxy, R is formula (II) ##STR2## in which V, W, Y and Z are hydrogen; X is a five- or six-membered heterocycle optionally substituted; and the heterocycle is optionally connected to the phenyl ring through a --O--, --S-- --CH.sub.2)p--, or --O(CR.sup.3 R.sup.4)q linkage; R.sup.1 and R.sup.2 are independently selected from phenyl or pyridyl substituted with haloalkyl or haloalkoxy; R.sup.3, R.sup.4, n, p, and 1 are as defined in the specification.Type: GrantFiled: August 11, 1998Date of Patent: February 29, 2000Assignee: FMC CorporationInventors: Ian R. Silverman, Daniel H. Cohen, John W. Lyga, Steven W. Szczepanski, Syed F. Ali, Thomas G. Cullen, Robert N. Henrie, II, Clinton J. Peake
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Patent number: 5939438Abstract: It has now been found that certain novel oximino and hydrazono derivatives of N-benzyl-4-benzhydryl- and 4-benhydrolpiperidines, and their corresponding N-oxides and agriculturally acceptable salts are useful as insecticides. These compounds are represented by Formula I: where R is hydrogen, halogen, alkyl, alkoxy, dialkylamino; R.sup.1 is hydrogen, alkyl, haloalkyl, alkoxyalkyl, alkylcarbonyl and alkylaminocarbonyl; X is oxygen, or NR.sup.2, Q is fluoro and hydroxy; Z is halogen, haloalkyl, haloalkoxy, pentahalothio, haloalkylthio, haloalkylsulfinyl, haloalkylsulfonyl, and --OCF.sub.2 O-- attached to two adjacent carbon atoms of the phenyl ring; n is 0 or 1; and, when X is NR.sup.2, R.sup.2 is hydrogen, alkyl, alkylcarbonyl, alkoxycarbonyl, or R.sup.1 and R.sup.2 taken together may be --C.sub.m H.sub.2.spsb.m, or --C.sub.2 H.sub.4 OC.sub.2 H.sub.4 --, where m is 3-9. Preferred compounds include those where R is hydrogen; R.sup.Type: GrantFiled: September 9, 1998Date of Patent: August 17, 1999Assignee: FMC CorporationInventors: Walter H. Yeager, Ian R. Silverman, Robert N. Henrie, II, Thomas G. Cullen, Clinton J. Peake
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Patent number: 5874579Abstract: An insecticidal composition comprising, in admixture with an agriculturally acceptable carrier, an insecticidally effective amount of a 2,4-diaminoquinazoline compound of the formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.6, R.sup.7, W, X, Y, and Z are as defined herein; methods of using the same; novel 2,4-diaminoquinazolines per se; and intermediates in the preparation thereof.Type: GrantFiled: May 1, 1996Date of Patent: February 23, 1999Assignee: FMC CorporationInventors: Robert N. Henrie II, Clinton J. Peake, Thomas G. Cullen, Walter H. Yeager
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Patent number: 5712281Abstract: There is provided an insecticidal composition comprising, in admixture with an agriculturally acceptable carrier, an insecticidally effective amount of a tetrahydroquinazoline compound of the formula ##STR1## wherein R, R.sup.1, R.sup.2, R.sup.3, R.sup.5, R.sup.6, R.sup.7, R.sup.8, and R.sup.9 are as defined herein, and methods of using the same. Certain novel substituted-phenyl tetrahydroquinazoline compounds per se are also identified.Type: GrantFiled: May 23, 1995Date of Patent: January 27, 1998Assignee: FMC CorporationInventors: Thomas G. Cullen, Robert N. Henrie, II, Clinton J. Peake, Brian D. Bennett
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Patent number: 5710157Abstract: An insecticidal composition comprising, in admixture with an agriculturally acceptable carrier, an insecticidally effective amount of a 5-deazapteridine compound of the formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, U, V, and W are as defined herein; agriculturally acceptable salts thereof; methods for using the same; and certain novel 5-deazapteridine per se.Type: GrantFiled: January 2, 1996Date of Patent: January 20, 1998Assignee: FMC CorporationInventors: Robert N. Henrie, II, Clinton J. Peake, Thomas G. Cullen, Munirathnam Krishnappa Chaguturu, Partha Sarathi Ray, Brian D. Bennett
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Patent number: 5696259Abstract: This invention describes 2,4-diamino-5-iodopyrimidines II where R, R1, R2, and R3 are independently selected from hydrogen, alkyl, cycloalkyl, alkoxyalkyl, alkoxyalkoxyalkyl, and arylalkyl; or, R1 and R2, and R3 and R, each independently, when taken together with pentylene or 3-oxapentylene, form piperidine and morpholine ring systems respectively; and R4 is hydrogen or lower alkyl. These compounds are useful intermediates in the preparation of insecticides I where U is an optionally substituted alkenylene.Type: GrantFiled: July 22, 1996Date of Patent: December 9, 1997Assignee: FMC CorporationInventors: Robert N. Henrie, II, Clinton J. Peake, Thomas G. Cullen, Walter H. Yeager, Mary E. Brown, John W. Buser
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Patent number: 5639753Abstract: This invention relates to pteridine and 8-deazapteridine compounds and compositions containing the same which are useful for controlling insects in agricultural crops. These pteridines may be represented by the following structure: ##STR1## wherein R and R.sup.1 are independently selected from amino, lower alkylamino, di(lower alkyl)amino (e.g., --N(CH.sub.3).sub.2), or di(lower alkyl)aminomethyleneamino (e.g., --N.dbd.CHN(CH.sub.3).sub.2);R.sup.2 is hydrogen, amino, lower alkyl (e.g., --CH.sub.3, --CH(CH.sub.3).sub.2), di(lower alkyl)aminomethyleneamino, hydroxy, lower alkoxy, phenyl or substituted phenyl, haloalkylphenylalkyl (e.g., 3-trifluoromethylphenylmethyl);Q is N or CH;R.sup.3 is -(n).sub.m -R.sup.4, where m is 0 or 1; wherein, when m is 1,n is a bridging atom or moiety selected from oxygen, sulfur, sulfinyl, sulfonyl, lower alkylene (e.g., --CH.sub.2 --, or --CH.sub.2 CH.sub.2 --), lower alkenylene (e.g., --CH.dbd.CH--), lower alkynylene (e.g., --C.tbd.C--), lower haloalkenylene (e.g., --C(Cl).dbd.Type: GrantFiled: November 28, 1995Date of Patent: June 17, 1997Assignee: FMC CorporationInventors: Robert N. Henrie, II, Clinton J. Peake, Thomas G. Cullen, Albert C. Lew, Ian R. Silverman
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Patent number: 5627189Abstract: An insecticidal composition comprising, in admixture with an agriculturally acceptable carrier, an insecticidally effective amount of a compound of the formula: ##STR1## wherein R, R.sup.1, R.sup.2, R.sup.3, R.sup.7, R.sup.8, m, n, and p are as defined herein, and agriculturally acceptable salts thereof, and methods of using the same.Type: GrantFiled: November 8, 1995Date of Patent: May 6, 1997Assignee: FMC CorporationInventors: Robert N. Henrie, II, Clinton J. Peake, Thomas G. Cullen, Albert C. Lew, Munirathnam K. Chaguturu, Partha S. Ray, Walter H. Yeager
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Patent number: H1996Abstract: It has now been found that certain novel photostable agriculturally acceptable organic or inorganic salts of formula I are useful as insecticides: where R is alkoxycarbonyl, alkoxycarbonylamino, cycloalkylalkoxy, 2-alkyl-2H-tetrazol-5-yl, or 2-haloalkyl-2H-tetrazol-5-yl; R1 is trihaloalkyl, or trihaloalkoxy; n is 0, or 1; and, wherein said salts are derived from hydrochloric acid; hydrobromic acid; boric acid; phosphoric acid; maleic acid; fumaric acid; phthalic acid; salicylic acid optionally substituted with alkyl or halogen; D-glucuronic acid; the sulfonic acid R2SO3H where R2 is alkyl, haloalkyl, hydroxyalkyl, D-10-camphoryl, or phenyl optionally substituted with alkyl or halogen; the carboxylic acid R3CO2H where R3 is hydrogen, alkyl, trihaloalkyl, carboxyl, phenyl optionally substituted with alkyl or halogen, or pyridyl; the boronic acid R4B(OH)2 where R4 is alkyl or phenyl optionally substituted with alkyl or halogen; the phosphonic acid R5PO3H2 where R5 is alkyl, haloalkenyl, or pheType: GrantFiled: November 20, 1998Date of Patent: October 2, 2001Assignee: FMC CorporationInventors: Clinton J. Peake, Thomas G. Cullen, Robert N. Henrie, II, Jane A. Dybas
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Patent number: H2007Abstract: Compounds of the following structure are disclosed as effective insecticides: in which: A and B are independently lower alkyl; U is lower alkylidene, lower alkenylidene, or CH—Z, where Z is hydrogen, lower alkyl, lower cycloalkyl, or phenyl; R is phenyl or a dibenzocyclo(C5-8)alkyl, each optionally substituted, or where R3 and R4 are independently selected from phenyl, optionally substituted with, halogen, lower alkyl, lower haloalkyl, lower alkoxy, lower haloalkoxy, lower alkenyl, or phenyl; R1 is selected from a variety of substituents, including 3-R2, where R2 is where D, E, and G are hydrogen, hydroxy, halogen, cyano, hydroxy, lower alkyl, lower haloalkyl, lower alkoxy, nitro, lower haloalkylsuffonyloxy, lower alkylcarboxylato, lower alkylcarbonylamino, lower alkylcarbonyl, lower alkoxycarbonyl, arylcarbonylamino; D and E taken together may form the group —O(CH2)O—; J is hydrogen or lower alkyl; m is 2 or 3, n is 1, 2, or 3; and halogType: GrantFiled: January 9, 1997Date of Patent: December 4, 2001Assignee: FMC CorporationInventors: Ian R. Silverman, Syed F. Ali, Daniel H. Cohen, John W. Lyga, Kirk A. Simmons, Thomas G. Cullen
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Patent number: H1838Abstract: Compounds for control of insects and arcarids are disclosed and exemplified which are N-(arylalkyl)-4-[bis(substituted aryl)hydroxymethyl]azabicyclo[3.3. 1 .]nonanes and [3.2.1.]octanes, including N-oxides thereof, N-(substituted-oxy) derivatives thereof, and agriculturally acceptable salts thereof, having the formula: ##STR1## Certain novel intermediates for these pesticidal compounds are also disclosed.Type: GrantFiled: December 16, 1998Date of Patent: February 1, 2000Assignee: FMC CorporationInventors: Thomas G. Cullen, Ian Robert Silverman, Walter H. Yeager