Patents by Inventor Thomas G. Easton

Thomas G. Easton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fibrinolysis and fibrinogenolysis treatment
    Patent number: 5407673
    Abstract: Disclosed is a fibrinolysis and fibrinogenolysis treatment which includes parenterally introducing into the body of a human patient human plasmin in fibrinolytically and fibrinogenolytically active form at a concentration and for a time sufficient to permit fibrinolytically and fibrinogenolytically active human plasmin to reach a concentration about the site of any intravascular clot sufficient to lyse the clot and/or to reduce circulating fibrinogen levels.
    Type: Grant
    Filed: October 6, 1993
    Date of Patent: April 18, 1995
    Assignee: Orion Therapeutic Systems, Inc.
    Inventors: Edward Reich, Thomas G. Easton
  • Injection/activation apparatus
    Patent number: 5378232
    Abstract: Disclosed is apparatus for administration of a drug in active form, which includes means defining a prodrug reaction zone including an immobilized enzyme for modifying chemically a prodrug to a physiologically compatible, physiologically active drug form, means in communication with the reaction zone for establishing parenteral access to the body of a patient, and means for transporting a prodrug through the reaction zone at a rate sufficient to convert the prodrug to the active drug form and then into the body of a patient.
    Type: Grant
    Filed: August 28, 1991
    Date of Patent: January 3, 1995
    Assignee: Orion Therapeutic Systems, Inc.
    Inventors: Thomas G. Easton, Edward Reich
  • Fibrinolysis and fibrinogenolysis treatment
    Patent number: 5288489
    Abstract: Disclosed is a fibrinolysis and fibrinogenolysis treatment which includes parenterally introducing into the body of a human patient human plasmin in fibrinolytically and fibrinogenolytically active form at a concentration and for a time sufficient to permit fibrinolytically and fibrinogenolytically active human plasmin to reach a concentration about the site of an intravascular clot sufficient to lyse the clot and/or to reduce circulating fibrinogen levels.
    Type: Grant
    Filed: August 28, 1991
    Date of Patent: February 22, 1994
    Assignee: Orion Therapeutic Systems, Inc.
    Inventors: Edward Reich, Thomas G. Easton
  • Employment of a mereyanine dye for the detection of malignant leukocytic cells
    Patent number: 4424201
    Abstract: A method for the detection of malignant leukocytic cells which comprises:contacting a fluid containing malignant leukocytic cells with a merocyanine dye of the formula: ##STR1## wherein n=1-5; X=0 or S; R.sub.1 and R.sub.2 are the same or different C.sub.2 -C.sub.5 alkyl groups:wherein said dye is incorporated into said cells; separating the cells from the incubation mixture; and detecting said dyed cells. Fluorescence or radioactivity detection methods are preferred detecting means.
    Type: Grant
    Filed: November 28, 1978
    Date of Patent: January 3, 1984
    Assignee: Rockefeller University
    Inventors: Jay E. Valinsky, Edward Reich, Thomas G. Easton