Abstract: The present invention is directed to enhancing the immune response of a human in need of protection against IV infection by administering in vivo, into a tissue of the human, at least one polynucleotide comprising one or more regions of nucleic acid encoding an IV protein or a fragment, a variant, or a derivative thereof. The present invention is further directed to enhancing the immune response of a human in need of protection against IV infection by administering, in vivo, into a tissue of the human, at least one IV protein or a fragment, a variant, or derivative thereof. The IV protein can be, for example, in purified form or can be an inactivated IV, such as those present in inactivated IV vaccines. The polynucleotide is incorporated into the cells of the human in vivo, and an immunologically effective amount of an immunogenic epitope of an IV, or a fragment, variant, or derivative thereof is produced in vivo.

Abstract: The present invention is directed to enhancing the immune response of a human in need of protection against IV infection by administering in vivo, into a tissue of the human, at least one polynucleotide comprising one or more regions of nucleic acid encoding an IV protein or a fragment, a variant, or a derivative thereof. The present invention is further directed to enhancing the immune response of a human in need of protection against IV infection by administering, in vivo, into a tissue of the human, at least one IV protein or a fragment, a variant, or derivative thereof. The IV protein can be, for example, in purified form or can be an inactivated IV, such as those present in inactivated IV vaccines. The polynucleotide is incorporated into the cells of the human in vivo, and an immunologically effective amount of an immunogenic epitope of an IV, or a fragment, variant, or derivative thereof is produced in vivo.

Abstract: The present invention is directed to enhancing the immune response of a human in need of protection against IV infection by administering in vivo, into a tissue of the human, at least one polynucleotide comprising one or more regions of nucleic acid encoding an IV protein or a fragment, a variant, or a derivative thereof. The present invention is further directed to enhancing the immune response of a human in need of protection against IV infection by administering, in vivo, into a tissue of the human, at least one IV protein or a fragment, a variant, or derivative thereof. The IV protein can be, for example, in purified form or can be an inactivated IV, such as those present in inactivated IV vaccines. The polynucleotide is incorporated into the cells of the human in vivo, and an immunologically effective amount of an immunogenic epitope of an IV, or a fragment, variant, or derivative thereof is produced in vivo.

Abstract: A structural connector for connecting first and second structural members has a substantially planar first flange and an embossment in the first flange, and the embossment in the first flange is formed with first and second sections, the first section generally extending uniformly to a first level above the top surface of the substantially planar first flange, that is different from a level to which the second section generally uniformly extends, the first and second sections being joined to each other at a distinct transition portion where the embossment sharply descends from the level of the first section to the level of the second section. The structural connector can be made with a bend that forms a first member adjacent the first flange and the embossment can extend through the bend into the first member.

Abstract: A joist hanger used to attach a joist to a support member or header designed to minimize the noise caused by the rubbing of the members of the connection, during loading. The joist hanger includes a seat and a pair of side walls extending upwardly in spaced relationship therefrom to receive the end portion of an joist. The bottom of the joist rests on the seat, and the side faces of the joist extend upwardly therefrom in spaced relationship from the side walls of the hanger. Inwardly projecting guides formed in the side walls of the hanger, hold the joist at selected points, maintaining the spaced relationship between the sides walls of the hanger and the side faces of the joist. The inwardly projecting guides can be formed with embossed portions connected to the side walls of the joist. The joist hanger is also formed with back flanges and top flanges that are relatively narrow compared to the back flanges.

Abstract: A joist hanger used to attach a joist to a support member or header designed to minimize the noise caused by the rubbing of the members of the connection, during loading. The joist hanger includes a seat and a pair of side walls extending upwardly in spaced relationship therefrom to receive the end portion of an joist. The bottom of the joist rests on the seat, and the side faces of the joist extend upwardly therefrom in spaced relationship from the side walls of the hanger. Inwardly projecting guides formed in the side walls of the hanger, hold the joist at selected points, maintaining the spaced relationship between the sides walls of the hanger and the side faces of the joist. The inwardly projecting guides can be formed with embossed portions connected to the side walls of the joist. The joist hanger is also formed with back flanges and top flanges that are relatively narrow compared to the back flanges.

Abstract: A joist hanger used to attach a joist to a support member or header designed to minimize the noise caused by the rubbing of the members of the connection, during loading. The joist hanger includes a seat and a pair of side walls extending upwardly in spaced relationship therefrom to receive the end portion of an joist. The bottom of the joist rests on the seat, and the side faces of the joist extend upwardly therefrom in spaced relationship from the side walls of the hanger. Inwardly projecting guides formed in the side walls of the hanger, hold the joist at selected points, maintaining the spaced relationship between the sides walls of the hanger and the side faces of the joist. The inwardly projecting guides can be formed with embossed portions connected to the side walls of the joist. The joist hanger is also formed with back flanges and top flanges that are relatively narrow compared to the back flanges.

Abstract: The spacer comprises a plurality of strips interleaved with one another to form an eggcrate-type pattern defining essentially rectilinear cells for each fuel rod. Each strip includes a central body portion with cantilevered loop spring-like projections extending to opposite sides, with spring contact portions projecting inwardly. Stops are provided along each of the central body regions of the strips intermediate the loop springs that project to the opposite side of the strip. Adjoining walls have loop spring portions for biasing the rod into engagement with opposing stops whereby each fuel rod is supported at six contact points, i.e., four spring contact points and two hard stop contacts opposite the paired spring contacts.

Abstract: A spacer for a nuclear fuel bundle comprises a plurality of discrete, generally cylindrical ferrules, with each ferrule having a pair of circumferentially spaced fuel rod contacting portions along one side of the ferrule and three superposed openings in the ferrule along an opposite side thereof. A leaf spring having opposite end projecting portions and a central projecting portion is disposed between adjacent ferrules with the end projecting portions and the central portion disposed within the openings of the ferrule. The central portion includes a boss projecting inwardly for engagement against the fuel rod in one ferrule and the end projections contain bosses projecting inwardly and spaced from the fuel rod of the one ferrule. The end projections bear against an adjacent ferrule. The spring is captured between the two ferrules and contacts the ferrules at a plurality of laterally and vertically spaced contact points so that the spring is stabilized against flow-induced vibration.

Abstract: An analogue amplifier circuit has a gain stage comprising two differential operational amplifers (17, 18) and an error correction stage comprising two differential operational amplifiers (20, 21) each connected with its inputs across the inputs of a respective gain stage amplifier and its output connected to the non-inverting input of the other gain stage amplifier. A balanced output from the outputs of the two gain stage amplifiers (17, 18) may be provided or these two outputs may be fed to a final stage amplifier (22) to provide a single output.