Patents by Inventor Thomas G. Hazel

Thomas G. Hazel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10286010
    Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: May 14, 2019
    Assignee: Neuralstem, Inc.
    Inventors: Karl K. Johe, Thomas G. Hazel, Martin Marsala, Osamu Kakinohana
  • Publication number: 20170333484
    Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
    Type: Application
    Filed: July 27, 2017
    Publication date: November 23, 2017
    Inventors: Karl K. Johe, Thomas G. Hazel, Martin Marsala, Osamu Kakinohana
  • Patent number: 9744194
    Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: August 29, 2017
    Assignees: Neuralstem, Inc., The Regents of the University of California
    Inventors: Karl K. Johe, Thomas G. Hazel, Martin Marsala, Osamu Kakinohana
  • Publication number: 20160228471
    Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
    Type: Application
    Filed: November 30, 2015
    Publication date: August 11, 2016
    Inventors: Karl K. Johe, Thomas G. Hazel, Martin Marsala, Osamu Kakinohana
  • Patent number: 9220730
    Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: December 29, 2015
    Assignees: Neuralstem, Inc., The Regents of the University of California
    Inventors: Karl K. Johe, Thomas G. Hazel, Martin Marsala, Osamu Kakinohana
  • Publication number: 20130251686
    Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
    Type: Application
    Filed: May 9, 2013
    Publication date: September 26, 2013
    Applicants: Regents of the University of California, NeuralStem, Inc.
    Inventors: Karl K. Johe, Thomas G. Hazel, Martin Marsala, Osamu Kakinohana
  • Patent number: 8460651
    Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: June 11, 2013
    Assignees: Neuralstem, Inc., The Regents of the University of California
    Inventors: Martin Marsala, Osamu Kakinohana, Thomas G. Hazel, Karl K. Johe
  • Patent number: 8236299
    Abstract: A method of treating neurodegenerative conditions is provided. Neural stem cells may be implanted at and/or remote from a region of neuron degeneration. The methods can include isolating neural stem cells from regions where specific types of neurons corresponding to the neurons to be replaced are generated. The methods can include isolating neural stem cells secreting growth factors affecting the growth and/or regeneration of specific types of neuron. In this invention, we disclose a method of treating such disorders, including several neurodegenerative disorders arising from the lack of cells that produce particular neurotransmitters in neural circuitry by transplanting exogenously cultured and expanded neural progenitors which, upon transplantation into a neural tissue, differentiate into neurons capable of integrating and producing neurotransmitters in sufficient quantities and in a sufficient manner to overcome the symptoms associated with the neurodegeneration.
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: August 7, 2012
    Assignee: NeuralStem, Inc.
    Inventors: Karl K. Johe, Thomas G. Hazel
  • Publication number: 20100239541
    Abstract: A method of treating neurodegenerative conditions is provided. Neural stem cells may be implanted at and/or remote from a region of neuron degeneration. The methods can include isolating neural stem cells from regions where specific types of neurons corresponding to the neurons to be replaced are generated. The methods can include isolating neural stem cells secreting growth factors affecting the growth and/or regeneration of specific types of neuron. In this invention, we disclose a method of treating such disorders, including several neurodegenerative disorders arising from the lack of cells that produce particular neurotransmitters in neural circuitry by transplanting exogenously cultured and expanded neural progenitors which, upon transplantation into a neural tissue, differentiate into neurons capable of integrating and producing neurotransmitters in sufficient quantities and in a sufficient manner to overcome the symptoms associated with the neurodegeneration.
    Type: Application
    Filed: February 22, 2010
    Publication date: September 23, 2010
    Applicant: Neuralsterm, Inc.
    Inventors: Karl K. Johe, Thomas G. Hazel
  • Patent number: 7691629
    Abstract: A method of treating neurodegenerative conditions is provided. Neural stem cells may be implanted at and/or remote from a region of neuron degeneration. The methods can include isolating neural stem cells from regions where specific types of neurons corresponding to the neurons to be replaced are generated. The methods can include isolating neural stem cells secreting growth factors affecting the growth and/or regeneration of specific types of neuron. In this invention, we disclose a method of treating such disorders, including several neurodegenerative disorders arising from the lack of cells that produce particular neurotransmitters in neural circuitry by transplanting exogenously cultured and expanded neural progenitors which, upon transplantation into a neural tissue, differentiate into neurons capable of integrating and producing neurotransmitters in sufficient quantities and in a sufficient manner to overcome the symptoms associated with the neurodegeneration.
    Type: Grant
    Filed: November 17, 2005
    Date of Patent: April 6, 2010
    Assignee: Neuralstem, Inc.
    Inventors: Karl K. Johe, Thomas G. Hazel
  • Publication number: 20100055075
    Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
    Type: Application
    Filed: March 16, 2009
    Publication date: March 4, 2010
    Applicants: NeuralStem, Inc., Regents of the University of California
    Inventors: Martin Marsala, Osamu Kakinohana, Thomas G. Hazel, Karl K. Johe
  • Patent number: 7188317
    Abstract: A first primary display window displays first primary objects linked to a scope window. A second primary display window displays second primary objects linked to the scope window. The second primary objects are independent of the first primary objects. One or more secondary display windows display secondary objects linked to one of the primary display windows. A secondary display window may be linked to the scope window so that the secondary objects displayed in the secondary display window are linked to the scope window. Data to create a window may be query-driven and the window type may be data-driven. Window type may be changed after creation and windows may be docked to each other to prevent overlap. Windows may link back to the scope window.
    Type: Grant
    Filed: June 13, 2001
    Date of Patent: March 6, 2007
    Assignee: Microsoft Corporation
    Inventor: Thomas G. Hazel