Patents by Inventor Thomas G. WEST

Thomas G. WEST has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11383440
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Grant
    Filed: January 16, 2018
    Date of Patent: July 12, 2022
    Assignee: APRECIA PHARMACEUTICALS LLC
    Inventors: Mahendra R. Patel, Amit S. Patel, Thomas J. Bradbury, Thomas G. West
  • Publication number: 20220211668
    Abstract: A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of water soluble drug in a porous matrix that disperses in water within a period of less than about 15 seconds is disclosed. Also disclosed are methods of preparing the dosage form and of treating a condition, disease or disorder that is therapeutically responsive to the drug.
    Type: Application
    Filed: March 24, 2022
    Publication date: July 7, 2022
    Inventors: JULES JACOB, NORMAN COYLE, THOMAS G. WEST, DONALD C. MONKHOUSE, HENRY L. SURPRENANT, NEMICHAND B. JAIN
  • Publication number: 20220183986
    Abstract: A method and system of forming a pharmaceutical dosage form within a portion of a blister packaging. The method includes the steps of providing a blister packaging for the dosage form with depressions. A predetermined amount of a drug-containing powder material comprising drug-containing particles is deposited into a substantially uniform powder layer within the depressions. A binding liquid is then deposited in a pattern on the powder layer within the depressions, to bind the particles of the powder layer and form an incremental wetted layer, Excess solvent in the binding material can be removed to form an incremental bound layer. These steps are repeated in sequence at least one or more times to form the pharmaceutical dosage form within the blister packaging.
    Type: Application
    Filed: March 2, 2022
    Publication date: June 16, 2022
    Inventors: Lauren E. Beach-Herrera, Matthew F. Boldt, Thomas J. Bradbury, Henry Cabral, Kelly E. Caputo, William R. Gross, Munhee Lee, Mahendra R. Patel, Aleece M. Phillips, Timothy S. Tracy, Thomas G. West, Jaedeok Yoo
  • Publication number: 20220126517
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Application
    Filed: August 20, 2021
    Publication date: April 28, 2022
    Inventors: Jaedeok YOO, Thomas J. BRADBURY, Thomas J. BEBB, James ISKRA, Henry L. SURPRENANT, Thomas G. WEST
  • Patent number: 11278501
    Abstract: A method and system of forming a pharmaceutical dosage form within a portion of a blister packaging. The method includes the steps of providing a blister packaging for the dosage form with depressions. A predetermined amount of a drug-containing powder material comprising drug-containing particles is deposited into a substantially uniform powder layer within the depressions. A binding liquid is then deposited in a pattern on the powder layer within the depressions, to bind the particles of the powder layer and form an incremental wetted layer. Excess solvent in the binding material can be removed to form an incremental bound layer. These steps are repeated in sequence at least one or more times to form the pharmaceutical dosage form within the blister packaging.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: March 22, 2022
    Assignee: APRECIA PHARMACEUTICALS LLC
    Inventors: Lauren E. Beach-Herrera, Matthew F. Boldt, Thomas J. Bradbury, Henry Cabral, Kelly E. Caputo, William R. Gross, Munhee Lee, Mahendra R. Patel, Aleece M. Phillips, Timothy S. Tracy, Thomas G. West, Jaedeok Yoo
  • Publication number: 20220054409
    Abstract: A rapidly-orodispersible dosage form comprising a porous, bound-powder matrix and one or more internal cavities is provided, as well as three-dimensional printing methods for making the same. Each internal cavity is configured to contain one or more payloads, particularly pharmaceutical medicaments, while isolating the payloads from the external environment outside of the dosage form. Each payload can be contained within its cavity in its native form without having to be combined with the bound-powder matrix or binding liquid. Dosage forms can disintegrate in water or saliva in less than two minutes, independently of the payload(s) or medicament(s) contained within. The dosage forms can be formed as unitary tablets, or as two-piece tablets comprising a container body and a lidding body that are secured together to isolate the one or more cavities and their payloads inside.
    Type: Application
    Filed: October 28, 2021
    Publication date: February 24, 2022
    Inventors: Jaedeok YOO, Aleece M. PHILLIPS, Thomas J. BRADBURY, Thomas G. WEST
  • Publication number: 20210393533
    Abstract: A method and system of forming a pharmaceutical dosage form within a portion of a blister packaging. The method includes the steps of providing a blister packaging for the dosage form with depressions. A predetermined amount of a drug-containing powder material comprising drug-containing particles is deposited into a substantially uniform powder layer within the depressions. A binding liquid is then deposited in a pattern on the powder layer within the depressions, to bind the particles of the powder layer and form an incremental wetted layer. Excess solvent in the binding material can be removed to form an incremental bound layer. These steps are repeated in sequence at least one or more times to form the pharmaceutical dosage form within the blister packaging.
    Type: Application
    Filed: October 15, 2019
    Publication date: December 23, 2021
    Inventors: Lauren E. Beach-Herrera, Matthew F. Boldt, Thomas J. Bradbury, Henry Cabral, Kelly E. Caputo, William R. Gross, Munhee Lee, Mahendra R. Patel, Aleece M. Phillips, Timothy S. Tracy, Thomas G. West, Jaedeok Yoo
  • Patent number: 11160786
    Abstract: A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of water soluble drug in a porous matrix that disperses in water within a period of less than about 15 seconds is disclosed. Also disclosed are methods of preparing the dosage form and of treating a condition, disease or disorder that is therapeutically responsive to the drug.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: November 2, 2021
    Assignee: APRECIA PHARMACEUTICALS LLC
    Inventors: Jules Jacob, Norman Coyle, Thomas G. West, Donald C. Monkhouse, Henry L. Surprenant, Nemichand B. Jain
  • Patent number: 11097483
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: August 24, 2021
    Assignee: APRECIA PHARMACEUTICALS LLC
    Inventors: Jaedeok Yoo, Thomas J. Bradbury, Thomas J. Bebb, James Iskra, Henry L. Surprenant, Thomas G. West
  • Publication number: 20200001521
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Application
    Filed: September 12, 2019
    Publication date: January 2, 2020
    Inventors: Jaedeok YOO, Thomas J. BRADBURY, Thomas J. BEBB, James ISKRA, Henry L. SURPRENANT, Thomas G. WEST
  • Patent number: 10449712
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: October 22, 2019
    Assignee: APRECIA PHARMACEUTICALS LLC
    Inventors: Jaedeok Yoo, Thomas J. Bradbury, Thomas J. Bebb, James Iskra, Henry L. Surprenant, Thomas G. West
  • Patent number: 10420785
    Abstract: A taste-masked rapidly dispersible dosage form of topiramate is provided. Wax coated particles of topiramate are included within a porous bound matrix. The topiramate retains its taste-masked form after dispersion in the mouth of a subject even though the particles are not coated with a polymeric material. The dosage form disperses in saliva or water in less than 2 min even though it has a high content of wax. It can be used to treat diseases or disorders that are therapeutically responsive to topiramate or a derivative thereof.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: September 24, 2019
    Assignee: APRECIA PHARMACEUTICALS LLC
    Inventors: Jules Jacob, Lauren Beach, Thomas G. West, Donald C. Monkhouse, Henry L. Surprenant
  • Publication number: 20190275730
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Application
    Filed: May 16, 2018
    Publication date: September 12, 2019
    Applicant: APRECIA PHARMACEUTICALS LLC
    Inventors: Jaedeok YOO, Thomas J. BRADBURY, Thomas J. BEBB, James ISKRA, Henry L. SURPRENANT, Thomas G. WEST
  • Patent number: 10118335
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Grant
    Filed: January 15, 2018
    Date of Patent: November 6, 2018
    Assignee: APRECIA PHARMACEUTICALS LLC
    Inventors: Jaedeok Yoo, Thomas J. Bradbury, Thomas J. Bebb, James Iskra, Henry L. Surprenant, Thomas G. West
  • Publication number: 20180296479
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Application
    Filed: June 22, 2018
    Publication date: October 18, 2018
    Applicant: APRECIA PHARMACEUTICALS LLC
    Inventors: Jules JACOB, Kelly CAPUTO, Micael GUILLOT, Kenneth J. SULTZBAUGH, Thomas G. WEST
  • Publication number: 20180264715
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Application
    Filed: May 16, 2018
    Publication date: September 20, 2018
    Applicant: APRECIA PHARMACEUTICALS LLC
    Inventors: Jaedeok YOO, Thomas J. BRADBURY, Thomas J. BEBB, James ISKRA, Henry L. SURPRENANT, Thomas G. WEST
  • Patent number: 10028909
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: July 24, 2018
    Assignee: APRECIA PHARMACEUTICALS LLC
    Inventors: Jules Jacob, Kelly Caputo, Micael Guillot, Kenneth J. Sultzbaugh, Thomas G. West
  • Publication number: 20180162042
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Application
    Filed: January 15, 2018
    Publication date: June 14, 2018
    Applicant: APRECIA PHARMACEUTICALS LLC
    Inventors: Jaedeok YOO, Thomas J. BRADBURY, Thomas J. BEBB, James ISKRA, Henry L. SURPRENANT, Thomas G. WEST
  • Publication number: 20180141275
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Application
    Filed: January 16, 2018
    Publication date: May 24, 2018
    Applicant: APRECIA PHARMACEUTICALS LLC
    Inventors: Mahendra R. PATEL, Amit S. PATEL, Thomas J. BRADBURY, Thomas G. WEST
  • Patent number: 9908293
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: March 6, 2018
    Assignee: APRECIA PHARMACEUTICALS LLC
    Inventors: Jaedeok Yoo, Thomas J. Bradbury, Thomas J. Bebb, James Iskra, Henry L. Surprenant, Thomas G. West