Patents by Inventor Thomas Gebhard

Thomas Gebhard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200141647
    Abstract: The present invention provides, inter alia, for a liquid feeding device for the generation of droplets, in particular for the use in a process line for the production of freeze-dried particles, with a droplet ejection section for ejecting liquid droplets in an ejection direction, the droplet ejection section comprising at least one inlet port for receiving a liquid to be ejected, a liquid chamber for retaining the liquid, and a nozzle for ejecting the liquid from the liquid chamber to form droplets, wherein the liquid chamber is restricted by a membrane on one side thereof, the membrane being vibratable by an excitation unit, wherein the longitudinal axis of the liquid chamber is tilted relative to the longitudinal axis of the nozzle, and/or the liquid feeding device further comprises a deflection section for separating the droplets from each other by means of at least one gas jet, wherein the deflection section gas jet intersects perpendicular with an ejection path of the liquid ejected from the liquid chamb
    Type: Application
    Filed: January 8, 2020
    Publication date: May 7, 2020
    Applicant: Sanofi Pasteur SA
    Inventors: Thomas GEBHARD, Roland KAISER, Bernhard LUY, Matthias PLITZKO, Manfred STRUSCHKA, Christian ZERILLO
  • Publication number: 20200116428
    Abstract: A heating device (124) for heating particles to be freeze-dried in a rotary drum (102) of a freeze-dryer (100) is provided, the device comprising at least one radiation emitter (202) for applying radiation heat to the particles, and a tube-shaped separator (204) for separating the particles from the at least one emitter (202), The separator (202) being integrally closed at one end and separating an emitter volume (206) encompassing the at least one emitter (202) from a drum process volume (126) inside the drum (102), wherein the heating device (124) protrudes into the drum process volume (126) such that said integrally closed end of the separator (204) is arranged inside the drum (102) as a free end.
    Type: Application
    Filed: October 16, 2019
    Publication date: April 16, 2020
    Applicant: Sanofi Pasteur SA
    Inventors: Thomas GEBHARD, Roland KAISER, Matthias PLITZKO, Manfred STRUSCHKA, Bernhard LUY
  • Publication number: 20200109896
    Abstract: A process line for the production of freeze-dried particles under closed conditions is provided, the process line comprising a freeze-dryer for the bulkware production of freeze-dried particles under closed conditions, the freeze-dryer comprising a rotary drum for receiving the frozen particles, and a stationary vacuum chamber housing the rotary drum, wherein for the production of the particles under closed conditions the vacuum chamber is adapted for closed operation during processing of the particles; the drum is in open communication with the vacuum chamber; and at least one transfer section is provided for a product transfer between a separate device of the process line and the freeze-dryer, the freeze-dryer and the transfer section being separately adapted for closed operation, wherein the transfer section comprises a temperature-controllable inner wall surface.
    Type: Application
    Filed: November 27, 2019
    Publication date: April 9, 2020
    Applicant: Sanofi Pasteur SA
    Inventors: Matthias Plitzko, Manfred Struschka, Thomas Gebhard, Bernhard Luy
  • Patent number: 10533800
    Abstract: The present invention provides, inter alia, for a liquid feeding device for the generation of droplets, in particular for the use in a process line for the production of freeze-dried particles, with a droplet ejection section for ejecting liquid droplets in an ejection direction, the droplet ejection section comprising at least one inlet port for receiving a liquid to be ejected, a liquid chamber for retaining the liquid, and a nozzle for ejecting the liquid from the liquid chamber to form droplets, wherein the liquid chamber is restricted by a membrane on one side thereof, the membrane being vibratable by an excitation unit, wherein the longitudinal axis of the liquid chamber is tilted relative to the longitudinal axis of the nozzle, and/or the liquid feeding device further comprises a deflection section for separating the droplets from each other by means of at least one gas jet, wherein the deflection section gas jet intersects perpendicular with an ejection path of the liquid ejected from the liquid chamb
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: January 14, 2020
    Assignee: Sanofi Pasteur SA
    Inventors: Thomas Gebhard, Roland Kaiser, Bernhard Luy, Matthias Plitzko, Manfred Struschka, Christian Zerillo
  • Patent number: 10527350
    Abstract: A process line for the production of freeze-dried particles under closed conditions is provided, the process line comprising a freeze-dryer (100) for the bulkware production of freeze-dried particles under closed conditions, the freeze-dryer (100) comprising a rotary drum (104, 302) for receiving the frozen particles, and a stationary vacuum chamber (102) housing the rotary drum (104, 302), wherein for the production of the particles under closed conditions the vacuum chamber (102) is adapted for closed operation during processing of the particles. The drum (104, 302) is in open communication with the vacuum chamber (102) and at least one transfer section (106, 108) is provided for a product transfer between a separate device of the process line and the freeze-dryer (100), the freeze-dryer (100) and the transfer section (106, 108) being separately adapted for closed operation, wherein the transfer section (106, 108) comprises a temperature-controllable inner wall surface.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: January 7, 2020
    Assignee: Sanofi Pasteur SA
    Inventors: Matthias Plitzko, Manfred Struschka, Thomas Gebhard, Bernhard Luy
  • Patent number: 10451345
    Abstract: A heating device (124) for heating particles to be freeze-dried in a rotary drum (102) of a freeze-dryer (100) is provided, the device comprising at least one radiation emitter (202) for applying radiation heat to the particles, and a tube-shaped separator (204) for separating the particles from the at least one emitter (202). The separator (202) being integrally closed at one end and separating an emitter volume (206) encompassing the at least one emitter (202) from a drum process volume (126) inside the drum (102), wherein the heating device (124) protrudes into the drum process volume (126) such that said integrally closed end of the separator (204) is arranged inside the drum (102) as a free end.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: October 22, 2019
    Assignee: Sanofi Pasteur SA
    Inventors: Thomas Gebhard, Roland Kaiser, Matthias Plitzko, Manfred Struschka, Bernhard Luy
  • Publication number: 20170219283
    Abstract: The present invention provides, inter alia, for a liquid feeding device for the generation of droplets, in particular for the use in a process line for the production of freeze-dried particles, with a droplet ejection section for ejecting liquid droplets in an ejection direction, the droplet ejection section comprising at least one inlet port for receiving a liquid to be ejected, a liquid chamber for retaining the liquid, and a nozzle for ejecting the liquid from the liquid chamber to form droplets, wherein the liquid chamber is restricted by a membrane on one side thereof, the membrane being vibratable by an excitation unit, wherein the longitudinal axis of the liquid chamber is tilted relative to the longitudinal axis of the nozzle, and/or the liquid feeding device further comprises a deflection section for separating the droplets from each other by means of at least one gas jet, wherein the deflection section gas jet intersects perpendicular with an ejection path of the liquid ejected from the liquid chamb
    Type: Application
    Filed: July 20, 2015
    Publication date: August 3, 2017
    Inventors: Thomas GEBHARD, Roland KAISER, Bernhard LUY, Matthias PLITZKO, Manfred STRUSCHKA, Christian ZERILLO
  • Patent number: 9347707
    Abstract: A rotary drum (302) for use within a vacuum chamber (212) in a vacuum freeze-dryer (204) for the bulkware production of freeze-dried particles is provided. The drum (302) is in open communication with the vacuum chamber (212) and comprises a main section (304) terminated by a front plate (306) and a rear plate (308), the rear plate (308) is adapted for connection with a rotary supporting shaft (312) for rotary support of the drum (302), and the rear plate (308) is permeable for sublimation vapor from freeze-drying the particles.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: May 24, 2016
    Assignee: Sanofi Pasteur SA
    Inventors: Manfred Struschka, Matthias Plitzko, Thomas Gebhard, Bernhard Luy
  • Publication number: 20150007445
    Abstract: A heating device (124) for heating particles to be freeze-dried in a rotary drum (102) of a freeze-dryer (100) is provided, the device comprising at least one radiation emitter (202) for applying radiation heat to the particles, and a tube-shaped separator (204) for separating the particles from the at least one emitter (202). The separator (202) being integrally closed at one end and separating an emitter volume (206) encompassing the at least one emitter (202) from a drum process volume (126) inside the drum (102), wherein the heating device (124) protrudes into the drum process volume (126) such that said integrally closed end of the separator (204) is arranged inside the drum (102) as a free end.
    Type: Application
    Filed: October 4, 2012
    Publication date: January 8, 2015
    Inventors: Thomas Gebhard, Roland Kasier, Matthias Plitzko, Manfred Struschka, Bernhard Luy
  • Publication number: 20140373383
    Abstract: A rotary drum (302) for use within a vacuum chamber (212) in a vacuum freeze-dryer (204) for the bulkware production of freeze-dried particles is provided. The drum (302) is in open communication with the vacuum chamber (212) and comprises a main section (304) terminated by a front plate (306) and a rear plate (308), the rear plate (308) is adapted for connection with a rotary supporting shaft (312) for rotary support of the drum (302), and the rear plate (308) is permeable for sublimation vapor from freeze-drying the particles.
    Type: Application
    Filed: October 4, 2012
    Publication date: December 25, 2014
    Applicant: SANOFI PASTEUR SA
    Inventors: Manfred Struschka, Matthias Plitzko, Thomas Gebhard, Bernhard Luy
  • Publication number: 20140237846
    Abstract: A process line for the production of freeze-dried particles under closed conditions is provided, the process line comprising a freeze-dryer (100) for the bulkware production of freeze-dried particles under closed conditions, the freeze-dryer (100) comprising a rotary drum (104, 302) for receiving the frozen particles, and a stationary vacuum chamber (102) housing the rotary drum (104, 302), wherein for the production of the particles under closed conditions the vacuum chamber (102) is adapted for closed operation during processing of the particles.
    Type: Application
    Filed: October 4, 2012
    Publication date: August 28, 2014
    Inventors: Matthias Plitzko, Manfred Struschka, Thomas Gebhard, Bernhard Luy