Abstract: Mass spectrometry techniques for determining the status of sepsis in an individual are provided. A biomarker profile resolved from a biological sample, taken from the individual, using a mass spectrometry technique is compared to a reference biomarker profile. A single such comparison classifies the individual as belonging to or not belonging to a reference population. The individual's biomarker profile and the reference biomarker profile comprise a plurality of ions each having a mass-to-charge ratio of about 100 Daltons to about 1000 Daltons. The plurality of ions can be detected by electrospray ionization mass spectrometry in positive mode. The comparison uses a decision rule, such as a classification tree, that determines the status of sepsis in the individual without requiring knowledge of the identity of the biomarkers in the biomarker profile from the individual and without requiring knowledge of the identity of the biomarkers in the reference biomarker profile.

Abstract: Certain embodiments of the present invention provide a method and system for using gaze detection to improve information display in a healthcare environment. Certain embodiments of a system include an eyewear headset for detecting a location of a user's gaze and a display for displaying information. Information on the display, such as images and/or data, is customized for the user based on the user's gaze. In an embodiment, the eyewear headset viewer projects information into the user's oculars for an individual information display. The system may also include a conflict resolution module for determining priority and control of the display among a plurality of users. In an embodiment, a function at the display may be triggered using a voice command, a gesture, and/or a gaze, for example.

Abstract: A gaming machine for conducting a wagering game comprises a processing apparatus and a secondary apparatus. To inhibit unauthorized persons from replacing some or all of the software executed by the processing apparatus with unapproved software, the processing apparatus transmits a security message to the secondary apparatus. The secondary apparatus, in turn, transmits an enable signal critical to machine function in response to successful validation of the security message. The secondary apparatus may, for example, be a programmable logic circuit external to the processing apparatus.

Abstract: Certain embodiments of the present invention provide for a system for patient dosimetry management including a processing component. The processing component is capable of receiving and/or aggregating dosimetry data from a plurality of information sources. Each information source in the plurality of information sources includes dosimetry data for a patient. The processing component is capable of generating patient dosimetry information based at least in part on the aggregated dosimetry data.

Abstract: Certain embodiments of the present invention provide systems and methods for correlating an acquired image with an historical image. Certain embodiments include registering an acquired image and at least one historical image according to a coordinate system, applying a metric to the acquired image and each of the historical image(s), and identifying a correlation between the acquired image and one of the historical image(s) based on the metric. Certain embodiments further include storing the correlation between the acquired image and an historical image for automatic linking of the acquired image and the historical image upon display. In certain embodiments, the acquired image and the historical image may be displayed based on the correlation. In certain embodiments, the acquired image and the historical image may be automatically linked based on the correlation. In certain embodiments, the metric analyzes the acquired image and at least one historical image based on anatomy.

Abstract: The present invention provides methods and compositions useful for the diagnosis or prognosis of a systemic inflammatory condition such as sepsis.

Abstract: Certain embodiments of the present invention provide a medical workflow system including a subvocal input device, an impulse processing component, and an information management system. The subvocal input device is capable of sensing nerve impulses in a user. The impulse processing component is in communication with the subvocal input device. The impulse processing component is capable of interpreting nerve impulses as dictation data and/or a command. The information management system is in communication with the impulse processing component. The information management system is capable of processing dictation data and/or a command from the impulse processing component.

Abstract: Certain embodiments of the present invention provide a system and method for automatic image post processing in a healthcare environment. In an embodiment, an automatic post processing image generation system includes at least one user interface, which is adapted to display at least one image on an image viewer and perform image post processing using at least one image post processing application. The system also includes at least one storage server capable of storing user data, wherein the user data includes at least one image and/or at least one post processing parameter. In addition, the system includes a post processing engine for automatically generating and displaying a current post processed image based on at least one image registration technique to correlate the at least one post processing parameter of a related previous post processed image with a current image.

Abstract: Certain embodiments of the present invention provide a system for improved conferencing and collaboration in a healthcare environment. The system includes an initiator workstation capable of sharing data over a network with a participant workstation and manipulating the shared data based at least in part on input from an initiator. The system also includes a participant workstation capable of manipulating the shared data based at least in part on input from a participant. The initiator and participant workstations are capable of simultaneous user manipulation of the shared data.

Abstract: Certain embodiments of the present invention provide a method and system for improved management of multiple applications and workflows using a workflow engine based dynamic worklist in a healthcare environment. In an embodiment, the system includes at least one data store, wherein the at least one data store includes departmental and/or enterprise information. The system also includes a plurality of databases, wherein the plurality of databases includes user tasks, user rules, and user preferences. In addition, the system includes a workflow engine for calculating and filtering the information obtained from the databases and data stores. The system also includes a worklist user interface, wherein the information calculated and filtered by the workflow engine is displayed.

Abstract: The present invention provides a computer-readable storage medium including a set of instructions for a computer. The instructions include an access routine, a tracking routine, and a modifying routine. The access routine is configured to communicate a default hanging protocol between a network server and a display workstation. The default hanging protocol includes at least one default display rule for displaying a plurality of images at the display workstation. The default display rule is capable of directing the display workstation to present each of the images at a location on a display device of the display workstation and/or in a sequence in which each of the images is presented at the display workstation. The tracking routine is configured to monitor a selection of an additional display rule. The modifying routine is configured to dynamically modify the default hanging protocol based on the selection.

Abstract: A gaming services framework comprises a set of services, protocols, XML schemas, and methods for providing gaming system functionality in a distributed, network based architecture that includes gaming machines and servers. Systems and methods provide a service-oriented framework for gaming and property management based upon internetworking technology and web services concepts. One aspect of the systems and methods includes a progressive service that operates to publish service details, receive registration requests from gaming machines and other clients, and provides progressive gaming services to the gaming machines and other clients.

Abstract: Certain embodiments of the present invention provide a method and system for using gaze detection to improve information display in a healthcare environment. Certain embodiments of a gaze detection and control system include an information system including information related to at least one image, a display device capable of displaying images and data, and a gaze tracking system for detection a location of a user's gaze with respect to the display device. The gaze tracking system triggers a retrieval of information from the information system based at least in part on the location of the user's gaze, and the retrieved information is displayed at the display device. In an embodiment, the retrieved information is overlaid over an image at the display device. In an embodiment, the gaze tracking system includes at least one camera and/or eyewear, for example.

Abstract: The present invention provides a computer-readable storage medium including a set of instructions for a computer. The instructions include an access routine, a tracking routine, and a modifying routine. The access routine is configured to communicate a default image processing workflow between a network server and a display workstation. The default image processing workflow includes at least one default image processing step for preparing at least one image for presentation to a user. The tracking routine is configured to monitor a selection of at least one additional image processing step to be applied to the image. The modifying routine is configured to modify the default workflow to alter the default workflow and/or add the at least one additional image processing step to the default image processing workflow.

Abstract: Certain embodiments of the present invention provide improved clinical workflow using a medical imaging and information management system and method with enhanced communication capabilities. Certain embodiments of the system include an information manager including clinical content, such as images and/or information, and a communication manager receiving an event notification from the information manager. The system may further include an interface capable of accessing the information manager. Additionally, the system may include a contact device capable of communicating via the communication manager. A modality may transmit examination data to the information manager and may receive instructions for the information manager. In an embodiment, the communications manager includes a contact information list with one or more contact devices associated with a user. The communications manager may be capable of detecting a presence of a user on a network.

Abstract: Certain embodiments of the present invention provide a system and method for real-time workflow management in a healthcare environment. The system includes a database, an optimizer engine, and an interface. The database includes resource information for a healthcare environment. The optimizer engine is capable of communicating with the database to extract resource information. The interface is capable of communicating with the optimizer engine and a user. The interface is capable of allocating a resource to manage a workflow based on output from the optimizer engine. In an embodiment, the optimizer engine is capable of making a recommendation based on the resource information. In an embodiment, the interface presents the recommendation to the user, and may present the recommendation based on a rule, for example. In an embodiment, the interface may include a map of resources. The user may direct workflow based in part on the interface and/or the recommendation.

Abstract: Methods for isolating a compound from a multipart, typically biological sample. The methods use at least one paramagnetic particle having an associated electronic charge to bind compounds with the opposite charge to form a particle/compound complex. Alternatively, the paramagnetic particles have a ligand or functional group with an affinity for a target compound to form a particle/compound complex. The complex can be immobilized by applying a magnetic field to the particle/protein complex. The sample may be further processed to obtain a protein sample in a more pure form or a sample depleted of select compounds.

Abstract: Certain embodiments of the present invention provide a method and system for using gaze detection to improve information display in a healthcare environment. Certain embodiments of a system include an eyewear headset for detecting a location of a user's gaze and a display for displaying information. Information on the display, such as images and/or data, is customized for the user based on the user's gaze. In an embodiment, the eyewear headset viewer projects information into the user's oculars for an individual information display. The system may also include a conflict resolution module for determining priority and control of the display among a plurality of users. In an embodiment, a function at the display may be triggered using a voice command, a gesture, and/or a gaze, for example.

Abstract: Certain embodiments of the present invention provide a method and system for improved diagnostic reading and workflow in a healthcare environment using rules-based context management. In an embodiment, the system includes a plurality of information sources, wherein each of the plurality of information sources includes information. The system also includes a rules engine including at least one rule governing at least one of availability and presentation of information. In addition, the system includes a context manager for obtaining information from the plurality of information sources based on a query and filtering the information based on the at least one rule. In an embodiment, the information sources include an information system and/or an imaging system, for example.

Abstract: Disclosed is an architecture for a network access server wherein a switching device is placed between a network gateway device and a first network, where the switching device detects the presence or absence of a security protocol field in the header information of data packets received from the first network and routes the data packets accordingly. When the security protocol field is absent, the switching device routes the data packet to the network gateway device for processing in accordance with a protocol service provided by the network access server. When the security protocol field is present, the switching device decrypts the data packet, processes the data packet in accordance with the protocol service provided by the network access server, and routes the data packet to another device within the network access server on the basis of decrypted address information within the data packet.