Patents by Inventor Thomas Giese

Thomas Giese has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190113989
    Abstract: A digit mounted stylus system includes a digit-cover having an open-end and a closed-end, and at least one raised protrusion configured on an outer surface of the digit-cover. The digit-cover is adapted to cover the tip of the digit of the user and enable a user to accurately use an electronic device via contact between the at least one raised protrusion and a screen of the electronic device. The device also allows for re-positioning of fingers and thumbs to relieve stress of single position use.
    Type: Application
    Filed: October 12, 2017
    Publication date: April 18, 2019
    Inventor: Thomas Giese
  • Patent number: 9664684
    Abstract: Described is a diagnostic method for predicting the response of a patient to chemovirotherapy or radiovirotherapy, comprising exposing primary tumor cells from a patient, e.g., tumor cells obtained from a brain tumor or pancreatic cancer, to (i) a parvovirus and/or (ii) a chemotherapeutic agent or radiotherapy, and determining the reduction of the expression or concentration of ISG15.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: May 30, 2017
    Assignees: Deutsches Krebsforschungszentrum, Ruprecht-Karls-Universitaet Heidelberg, Universitaetsklinikum Heidelberg
    Inventors: Nathalia Giese, Jens Werner, Markus Buechler, Thomas Giese, Laurent Daeffler, Celina Czeipluch, Jean Rommelaere, Zahari Raykov
  • Publication number: 20150152498
    Abstract: A method for generating a reference for determining the likelihood of response of a patient, suffering from a disease, towards immunoglobulin therapy comprising the steps of a) providing samples of a sufficient number of individuals, in particular at least 10 individuals, the samples containing B- and T-lymphocytes, natural killer cells, invariant T-cells and monocytes of the individuals; b) determination of values of immune parameters which are either static, such as leukocyte subpopulations and cytokine-level in the plasma or functional, like gene expression and cytokine release after lipopolysaccharide (LPS) and/or IVIG stimulation ex vivo; c) the determined values derived from immune parameters of the samples of the individuals are ordered in quartiles and the values belonging to the 1. quartile, values distributed at the low end of the corresponding parameter, are set to “?1”, whereas values distributed in the 4.
    Type: Application
    Filed: June 14, 2013
    Publication date: June 4, 2015
    Inventors: Stefan Meuer, Thomas Giese, Stefan Wietek
  • Publication number: 20130277628
    Abstract: A portable and self-contained prime mover arrangement. A base is positioned on a generally horizontal surface and is so stabilized and so balanced so as to be readily insertable under a vehicle requiring lifting off the generally horizontal surface while remaining in full contact with the generally horizontal surface during positioning under, and lifting or lowering, the vehicle. An electric motor is positioned on the base. A gear box is positioned on the base, and is operatively connected to the electric motor. A coupler is positioned on the base, is operatively connected to the gear box, receives, and thereby motorizes, either a conventional and pre-existing mechanical bottle jack or a conventional and pre-existing scissor jack. A handle is replaceably attached to the base, and readily inserts the portable and self-contained prime mover arrangement under the vehicle or removes the portable and self-contained prime mover arrangement from under the vehicle.
    Type: Application
    Filed: April 23, 2012
    Publication date: October 24, 2013
    Inventor: Thomas Giese
  • Publication number: 20130101989
    Abstract: Described is a diagnostic method for predicting the response of a patient to chemovirotherapy or radiovirotherapy, comprising exposing primary tumor cells from a patient, e.g., tumor cells obtained from a brain tumor or pancreatic cancer, to (i) a parvovirus and/or (ii) a chemotherapeutic agent or radiotherapy, and determining the reduction of the expression or concentration of ISG15.
    Type: Application
    Filed: April 29, 2011
    Publication date: April 25, 2013
    Applicants: DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFUNG DES OEFFE, UNIVERSITAETSKLINIKUM HEIDELBERG, RUPRECHT-KARIS-UNIVERSITAET HEIDELBERG
    Inventors: Nathalia Giese, Jens Werner, Markus Buechler, Thomas Giese, Laurent Daeffler, Celina Cziepluch, Jean Rommelaere, Zahari Raykov
  • Publication number: 20100330568
    Abstract: A method of determining a patient's susceptibility for NK cell modulation by immunoglobulins in response to a treatment of a disease or prophylaxis of a disease with immunoglobulins wherein a modulation of natural killer cells caused by said immunoglobulins is determined.
    Type: Application
    Filed: January 9, 2009
    Publication date: December 30, 2010
    Inventors: Stefan Meuer, Thomas Giese, Christian Jacobi, Jürgen Römisch, Stefan Haag
  • Publication number: 20080292729
    Abstract: Pharmaceutical compositions for treating neoplastic disorders and uses thereof are provided. Said pharmaceutical compositions comprise stabilized chlorite solutions (e.g. WFIO) and a fluoropyrimidine, 5-FU, or a 5-FU prodrug (e.g. capecitabine, doxifluridine, UFT, S-1, or BOF-A2). The use of the above stabilized chlorite solution in combination with a fluoropyrimidine dramatically improves the quality of life index (QOL) of a patient undergoing cancer chemotherapy. Cancers that can be treated include cancers of the pancreas, gastrointestinal, head, neck, and breast.
    Type: Application
    Filed: July 21, 2006
    Publication date: November 27, 2008
    Applicant: NUVO RESEARCH INC.
    Inventors: Stefan Meuer, Thomas Giese, Frederich-Wilhelm Kuhne
  • Publication number: 20050153853
    Abstract: A composition suitable for use in personal cleaning or detergent soap bars, which includes a sulfonated fatty acid or alpha sulfonated alkyl ester and a secondary synthetic surfactant, and methods for producing such a composition. The composition and methods exhibit efficient processing and allow for formation of cleansing or detergent bars with improved hardness, improved resistance to marring and improved processability, lowered wear-rate and decreased mush formation during consumer use.
    Type: Application
    Filed: December 8, 2004
    Publication date: July 14, 2005
    Inventors: Branko Sajic, Carlos Ospinal, Chris Felski, Minh Tong, Thomas Giese, Matthew Levinson
  • Publication number: 20040023246
    Abstract: The present invention is based on the surprising observation, that a high degree of expression of certain distinct Genes in peripheral blood mononuclear cells is associated with in inflammatory process with a higher probability than it is the case for other Genes. Therefore, the present invention provides a method for diagnosis of an inflammatory process comprising monitoring expression levels of 4-6 selected targets in peripheral blood mononuclear cells as compared to expression levels of said selected targets in peripheral blood mononuclear cells in healthy individuals, characterized in that over-expression or repression of the majority of said selected Genes is indicative for an inflammatory process.
    Type: Application
    Filed: December 6, 2002
    Publication date: February 5, 2004
    Inventors: Stefan Meuer, Thomas Giese
  • Patent number: D611516
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: March 9, 2010
    Assignee: Prym Consumer USA Inc.
    Inventors: George McConnell Davison, III, Peter Arthur Meier, Timothy Adam Craig, Jason Reed Rogge, Colin Derek Curry, Casey Anne Tustin, Thomas Giese