Patents by Inventor Thomas Gobel

Thomas Gobel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7795442
    Abstract: A process is provided for preparing compounds having the general formula I wherein R is a range of organic groups and X is a leaving group. The process comprises reacting a compound of formula II with a water-removing reagent. When X is halogen or a sulfonate, the compound of formula I may be prepared by reacting a compound of the formula III with a halogenating agent or a sulfonylating agent. Alternatively, when X is halogen, the compound of formula I can be prepared by reacting a compound of the formula IV where R2 and R2 are defined organic groups, with a compound of the formula halogen-C(—O)—O—C1-C8alkyl, halogen-C(—O)—O-aryl or halogen-C(—O)—O-benzyl.
    Type: Grant
    Filed: April 16, 2009
    Date of Patent: September 14, 2010
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Mainenfisch, Ottmar Franz Huter, Thomas Rapold, Marcel Senn, Thomas Gobel, Anthony Cornelius O'Sullivan
  • Publication number: 20090198054
    Abstract: The present disclosure is directed to a process for the preparation of a compound having the formula: wherein R is unsubstituted or substituted C1-C12alkyl, unsubstituted or substituted C2-C4alkenyl, unsubstituted or substituted C2-C4alkynyl, unsubstituted or substituted C3-C6cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, or —SR1; R1 is unsubstituted or substituted C1-C12alkyl, unsubstituted or substituted C2-C4alkenyl, unsubstituted or substituted C2-C4alkynyl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; and X is a selected leaving group that is not halogen, and may specifically be methylsulfonate, trifluoromethylsulfonate, and p-toluenesulfonate. These compounds are valuable intermediates useful in the synthesis of compounds having pesticidal activity.
    Type: Application
    Filed: April 16, 2009
    Publication date: August 6, 2009
    Applicant: SYNGENTA CROP PROTECTION, INC.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Franz Huter, Thomas Rapold, Marcel Senn, Thomas Gobel, Anthony Cornelius O'Sullivan
  • Patent number: 7538229
    Abstract: A process for the preparation of a compound of formula I wherein R is a range of organic groups and X is a leaving group which process comprises a) reacting a compound of the formula II where R is defined for formula (I) with a water-removing reagent; or b) for the preparation of a compound of formula (I) wherein K is halogen or a sulfonate, reacting a compound of the formula III where R is defined for formula (I) with a halogenating agent or a sulfonylating agent; or c) for the preparation of a compound of formula (I) wherein X is halogen, reacting a compound of the formula IV where R is as defined for formula (I) and R2 and R3 are defined organic groups with a compound of the formula halogen-C(—O)—O—C1-C8alkyl, halogen-C(—O)—O-aryl or halogen-C(—O)—O-benzyl.
    Type: Grant
    Filed: November 30, 2007
    Date of Patent: May 26, 2009
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Franz Huter, Thomas Rapold, Marcel Senn, Thomas Gobel, Anthony Cornelius O'Sullivan
  • Publication number: 20080076920
    Abstract: The present disclosure is directed to a process for the preparation of a compound having the formula: wherein R is unsubstituted or substituted C1-C12alkyl, unsubstituted or substituted C2-C4alkenyl, unsubstituted or substituted C2-C4alkynyl, unsubstituted or substituted C3-C6cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, or —SR1; R1 is unsubstituted or substituted C1-C12alkyl, unsubstituted or substituted C2-C4alkenyl, unsubstituted or substituted C2-C4alkynyl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; and X is a selected leaving group that is not halogen, and may specifically be methylsulfonate, trifluoromethylsulfonate, and p-toluenesulfonate. These compounds are valuable intermediates useful in the synthesis of compounds having pesticidal activity.
    Type: Application
    Filed: November 30, 2007
    Publication date: March 27, 2008
    Applicant: SYNGENTA CROP PROTECTION, INC.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Huter, Thomas Rapold, Marcel Senn, Thomas Gobel, Anthony O'Sullivan
  • Patent number: 7323564
    Abstract: The present invention is directed to a process for preparing a compound having the formula: wherein R is a range of organic groups and X is a leaving group. The process may include reacting a compound of the formula with a water-removing reagent. Also, when X is a halogen, the process may include reacting a compound of the formula with a halogenating agent or a sulfonylating agent. Alternatively, when X is a halogen, the process may be carried out by reacting a compound of the formula IV where R2 and R3 are defined organic groups with a compound of the formula halogen-C(—O)—O—C1 -C8alkyl, halogen-C(—O)—O-aryl or halogen-C(—O)—O-benzyl.
    Type: Grant
    Filed: October 24, 2006
    Date of Patent: January 29, 2008
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Franz Huter, Thomas Rapold, Marcel Senn, Thomas Gobel, Anthony O'Sullivan
  • Publication number: 20070055063
    Abstract: A process for the preparation of a compound of the formula and, where applicable, its E/Z-isomers, mixtures of E/Z-isomers and/or tautomers and acid addition products thereof, in each case in free form or in salt form, wherein: R is unsubstituted or substituted C1-C12alkyl, unsubstituted or substituted C2-C4alkenyl, unsubstituted or substituted C2-C4alkynyl, unsubstituted or substituted C3-C6cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, or —SR1; R1 is unsubstituted or substituted C1-C12alkyl, unsubstituted or substituted C2-C4alkenyl, unsubstituted or substituted C2-C4alkynyl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted aryl or unsubstituted or substituted heteroaryl; and X is a leaving group; The process comprises reacting a compound of the formula: with a halogenating agent or a sulfonylating agent.
    Type: Application
    Filed: October 24, 2006
    Publication date: March 8, 2007
    Applicant: SYNGENTA CROP PROTECTION, INC.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Huter, Thomas Rapold, Marcel Senn, Thomas Gobel, Anthony O'Sullivan
  • Patent number: 7161011
    Abstract: Described is a process for the preparation of a compound of the formula wherein R is unsubstituted or substituted C1–C12alkyl, C2–C4alkenyl, C2–C4alkynyl, C3–C6cycloalkyl, aryl or heteroaryl, or —SR1; R1 is unsubstituted or substituted C1–C12alkyl, C2–C4alkenyl, C2–C4alkenyl, C2–C4alkynyl, cycloalkyl, aryl or heteroaryl; and X is a leaving group; which comprises a) reacting a compound of the formula wherein R is as defined for formula (I), with a water removing reagent.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: January 9, 2007
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Franz Hüter, Thomas Rapold, Marcel Senn, Thomas Göbel, Anthony Cornelius O'Sullivan
  • Publication number: 20040061059
    Abstract: The invention relates to a medical probe for measuring radioactive radiation, comprising a housing that can be held single-handedly. A detector device (2) comprising a semiconductor diode is disposed in the housing and produces signals that interact with at least one of the following radioactive radiations: &agr;&bgr;+, &bgr;−and &ggr; radiation. A signal processing device (3) processes the signals produced by the detector device (2). A power supply device (4) provides the detector device (2) and the signal processing device (3) with power. The inventive probe is especially characterized in that a reproduction device (5) for reproducing the signals processed by means of the signal processing device (3) is mounted in the housing (1). The inventive device provides a compact measuring system that facilitates an (especially wireless) flexible intraoperative and extraoperative, local measurement of radioactively labeled tissue without requiring additional appliances.
    Type: Application
    Filed: October 24, 2003
    Publication date: April 1, 2004
    Inventors: Thomas Gobel, Olaf Hug
  • Publication number: 20040061375
    Abstract: The present invention relates to an electrohydraulic brake system for motor vehicles which is controllable in a ‘brake-by-wire’ mode of operation by the vehicle operator as well as irrespective of the vehicle operator, is operated preferably in the brake-by-wire mode of operation, and can be operated in a fallback mode of operation in which only operation by the vehicle operator is possible.
    Type: Application
    Filed: August 7, 2003
    Publication date: April 1, 2004
    Inventors: Peter Drott, Bernhard Giers, Thomas Gobel, Horst Kramer, Holger Kranlich, Andreas Klein, Holger Wahl, Jan Hoffmann, Andreas Emmerich, Uwe Karl
  • Patent number: 6677457
    Abstract: The invention relates to a process for the preparation of a compound of the formula wherein Q, Y, Z, R1, R2, R3, R4 and R5 are as defined in the specification, which comprises a) reacting a compound of the formula  with a halogenating agent to form a compound of the formula or b) converting a compound of formula (II) by means of a halogenating agent into a compound of the formula optionally c) converting the compound of formula (IV) into a compound of formula (III); d) converting a compound of formula (III) by means of a compound of the formula into a compound of the formula or e) converting a compound (IV) by means of a compound (V) into a compound (VI); and f) converting a compound (VI) by means of a chlorinating agent into a compound (I); a compound (IV); to a process for the preparation of a compound (III) and to a process for the preparation of a compound (IV).
    Type: Grant
    Filed: January 15, 2002
    Date of Patent: January 13, 2004
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Franz Hüter, Thomas Rapold, Marcel Senn, Thomas Göbel, Anthony Cornelius O'Sullivan, Gottfried Seifert
  • Publication number: 20030216579
    Abstract: Described is a process for the preparation of a compound of the formula 1
    Type: Application
    Filed: March 27, 2003
    Publication date: November 20, 2003
    Inventors: Thomas Pitterna, Thomas Rapold, Marcel Senn, Thomas Gobel, Anthony Cornelius O'Sullivan
  • Patent number: 6548676
    Abstract: Described is a process for the preparation of a compound of formula (I) wherein R is unsubstituted or substituted C1-C12alkyl, C2-C4alkenyl, C2-C4alkynyl, C3-C6cycloalkyl, aryl or heteroaryl, or —SR1; R1 is unsubstituted or substituted C1-C12alkyl, C2-C4alkenyl, C2-C4alkynyl, cycloalkyl, aryl or heteroaryl; and X is a leaving group; which comprises: a) reacting a compound of formula (II) wherein R is as defined for formula (I), with a water-removing reagent; or b) for the preparation of a compound of formula (I) wherein X is halogen or a sulfonate, reacting a compound of the formula (III) wherein R is as defined for formula (I), with a halogenating or a sulfonylating agent; or c) for the preparation of a compound of formula (I) wherein X is halogen, reacting a compound of formula (IV) wherein R is as defined for formula (I); and wherein R2 and R3 are for example H, C1-C6alkyl, C3-C6cycloalkyl, phenyl or benzyl; with a compound of the formula halogen-C(═O)—O—C1-C8alkyl, halogen-C(═O
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: April 15, 2003
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Franz Hüter, Thomas Rapold, Marcel Senn, Thomas Göbel, Anthony Cornelius O'Sullivan
  • Publication number: 20030065191
    Abstract: The invention relates to a process for the preparation of a compound of the formula 1
    Type: Application
    Filed: January 15, 2002
    Publication date: April 3, 2003
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Franz Huter, Thomas Rapold, Marcel Senn, Thomas Gobel, Anthony Cornelius O'Sullivan, Gottfried Seifert
  • Patent number: 6369233
    Abstract: The Invention relates to a process for the preparation of a compound of the formula wherein Q, Y, Z, R1, R2, R3, R4 and R5 are as defined in the specification, which comprises a) reacting a compound of the formula  with a halogenating agent to form a compound of the formula b) converting a compound of formula (II) by means of a halogenating agent into a compound of the formula  optionally c) converting the compound of formula (IV) into a compound of formula (III); d) converting a compound of formula (III) by means of a compound of the formula e) converting a compound (IV) by means of a compound (V) into a compound (VI); and f) converting a compound (VI) by means of a chlorinating agent into a compound (I); a compound (IV); to a process for the preparation of a compound (III) and to a process for the preparation of a compound (IV).
    Type: Grant
    Filed: August 1, 2000
    Date of Patent: April 9, 2002
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Franz Hüter, Thomas Rapold, Marcel Senn, Thomas Göbel, Anthony Cornelius O'Sullivan, Gottfried Seifert
  • Publication number: 20020040027
    Abstract: A method for the systemic control of blood-sucking parasites in warm-blooded animals or for the prevention of reinfestation, which comprises administering systemically to the warm-blooded animal a compound of formula 1
    Type: Application
    Filed: October 5, 2001
    Publication date: April 4, 2002
    Inventors: Friedrich Karrer, Thomas Gobel, Elaine Humbert-Droz
  • Patent number: 6224660
    Abstract: The ink mixture contains at least one organosilane and optionally at least one hydrophobic silicic acid. The ink mixture can be used as a printing ink, especially as an ink for ink-jet printing.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: May 1, 2001
    Assignee: Degussa-Huls Aktiengesellschaft
    Inventors: Andreas Stübbe, Wolfgang Lortz, Thomas Göbel, Holger Glaum
  • Patent number: 6211381
    Abstract: The invention relates to a process for preparing a compound of formula (I), in which X is CH or N, Y is NO2 or CN, Z is CHR3, O, NR3 or S, R1 and R2 are either each, independently of the other, hydrogen or unsubstituted or R4-substituted alkyl or together a two- or three-membered alkylene bridge or a two- or three-membered alkylene bridge in which one member is replaced by a hetero member selected from the group, consisting of NR5, O and S, R3 is H or unsubstituted or R4-substituted alkyl, R4 is an unsubstituted or substituted aryl or heteroaryl group, and R5 is H or alkyl, which comprises a) reacting a compound of formula (II) with a chlorinating agent or b1) initially reacting a compound of formula (IV) with a compound of formula (V) and b2) further reacting the compound of formula (II) obtainable thereby, with or without intermediate isolation, with a chlorinating agent, to intermediates used in this process, to the use of these intermediates and to a process for the preparation of these intermediates.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: April 3, 2001
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Henry Szczepanski, Thomas Göbel, Ottmar Franz Hüter, Anthony Cornelius O'Sullivan, Marcel Senn, Thomas Rapold, Peter Maienfisch, Thomas Pitterna
  • Patent number: 6139622
    Abstract: This invention relates to a process for the production of a homogeneously waterproofed concrete (integrally waterproofed concrete) in which an aqueous hydrolysable, emulsion containing organosilicon compounds is added before curing to the fresh concrete mix prepared from water, inorganic and optionally organic constituents, which emulsion contains at least one alkoxysilane and optionally an organosilicon compound acting as a surfactant.
    Type: Grant
    Filed: October 30, 1998
    Date of Patent: October 31, 2000
    Assignee: Degussa-Huls AG
    Inventors: Thomas Gobel, Wolfgang Lortz, Reiner Storger, Folker Wittmann, Andreas Gerdes
  • Patent number: 6121455
    Abstract: The invention relates to a process for the preparation of a compound of the formula ##STR1## and, where applicable, its E/Z-isomers, mixtures of E/Z-isomers and/or tautomers, in each case in free form or in salt form, whereinQ is CH or N,Y is NO.sub.2 or CN,Z is CHR.sub.3, O, NR.sub.3 or S,R.sub.1 and R.sub.2 are either each independently of the other hydrogen or unsubstituted or R.sub.4 -substituted C.sub.1 -C.sub.8 alkyl, or together form an alkylene bridge having two or three carbon atoms, and said alkylene bridge may additionally contain a hetero atom selected from the group consisting of NR.sub.5, O and S,R.sub.3 is H or unsubstituted or R.sub.4 -substituted C.sub.1 -C.sub.12 alkyl,R.sub.4 is unsubstituted or substituted aryl or heteroaryl, andR.sub.5 is H or C.sub.1 -C.sub.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: September 19, 2000
    Assignee: Novartis Crop Protection, Inc.
    Inventors: Thomas Pitterna, Henry Szczepanski, Peter Maienfisch, Ottmar Franz Huter, Thomas Rapold, Marcel Senn, Thomas Gobel, Anthony Cornelius O'Sullivan, Gottfried Seifert
  • Patent number: 5996539
    Abstract: A method for actuating an electromagnetic actuator for a cylinder (gas exchange) valve of a piston-type internal combustion engine, wherein the actuator has two spaced electromagnets and an armature which is operatively connected to the cylinder valve and which is guided movably, as a function of the current supplied to the electromagnet by a control unit, in the closing direction counter to the force of an opener spring and in the opening position counter to the force of a closing spring, and for the normal stroke of the gas exchange valve, the armature is kept via the springs at the same spacing from the two electromagnets when the electromagnets are without current. To shorten the valve stroke during operation, the prestressing of one of the two springs, preferably the opener spring, is variable via an adjusting device which is triggered or controlled via the engine control unit.
    Type: Grant
    Filed: July 31, 1998
    Date of Patent: December 7, 1999
    Assignee: FEV Motorentechnik GmbH & Co KG
    Inventors: Thomas Gobel, Thomas Esch