Abstract: The invention concerns a kit and a syringe for use in a therapeutic method for intracutaneous filling of the collagen structure in connective tissue of the skin, and the use thereof, particularly as part of the treatment of skin defects, particularly skin diseases and signs of skin aging.

Abstract: The invention concerns a kit and a syringe for use in a therapeutic method for intracutaneous filling of the collagen structure in connective tissue of the skin, and the use thereof, particularly as part of the treatment of skin defects, particularly skin diseases and signs of skin aging.

Abstract: The invention relates to the preparation and provision of a gelling collagen composition that instantaneously forms a collagen matrix, and means for the preparation and use thereof, in particular as part of a therapeutic treatment.

Abstract: The present invention relates to methods for cultivating dermal fibroblasts, methods for preparing in vitro dermis equivalents, methods for preparing three-dimensional in vitro skin equivalents, an in vitro dermis equivalent, a three-dimensional in vitro skin equivalent, and methods for determining the effect of a chemical substance or of an agent on human skin cells using the in vitro dermis equivalent and/or the in vitro skin equivalent.

Abstract: The present invention relates to methods for cultivating dermal fibroblasts, methods for preparing in vitro dermis equivalents, methods for preparing three-dimensional in vitro skin equivalents, an in vitro dermis equivalent, a three-dimensional in vitro skin equivalent, and methods for determining the effect of a chemical substance or of an agent on human skin cells using the in vitro dermis equivalent and/or the in vitro skin equivalent.

Abstract: The present invention relates to methods for cultivating dermal fibroblasts, methods for preparing in vitro dermis equivalents, methods for preparing three-dimensional in vitro skin equivalents, an in vitro dermis equivalent, a three-dimensional in vitro skin equivalent, and methods for determining the effect of a chemical substance or of an agent on human skin cells using the in vitro dermis equivalent and/or the in vitro skin equivalent.

Abstract: The invention relates to a biomatrix as well as to a method of manufacturing same. In order to provide a biologically and mechanically satisfying replacement for diseased cartilage for example, a biomatrix is proposed in which the matrix is condensed or solidified. A corresponding method is moreover proposed.

Abstract: The invention relates to a bioreactor as well as a method for cultivating organic material: in particular cells, by means of a nutrient medium. For an intensive cultivation of the organic material in a simple and reliable handling a flow generating device is provided in the bioreactor according to the invention, by means of which the nutrient medium can be put into a flow, wherein a receiving device is arranged in the flow that is adapted for receiving and/or retaining the organic material and wherein the receiving device that is adapted for passing through the flowing nutrient medium is permeable. The method in accordance with the invention is characterized in that the nutrient medium is at least temporarily put into a flow, that the organic material, in particular cells, is retained in or at a receiving device, which is permeable to the nutrient medium and that the nutrient medium is passed through the receiving device.

Abstract: The present invention relates to a reactor module constructed of hollow fibers and cells as well as to reactors comprising this reactor module.

Abstract: The present invention relates to a reactor module constructed of hollow fibers and cells as well as to reactors comprising this reactor module.

Abstract: The present invention relates to methods for cultivating cartilage cells, methods for redifferentiating dedifferentiated cartilage cells, as well as cartilage transplants.

Abstract: This present invention relates to means and methods for analyzing and diagnosing infections in humans or animals caused by pathogenic and/or parasitic microorganisms, means and methods for analyzing and diagnosing degenerated or genetically engineered human or animal cells, as well as means and methods for investigating and testing anti-infective agents and medications against tumors, as well as three-dimensional in vitro organ and tissue models, in particular of tissues susceptible for infections, such as intestines, skin, cornea, trachea, and mucous membranes.