Abstract: The invention provides a compound of formula (I): or a prodrug thereof, or a pharmaceutically acceptable salt thereof, wherein R1 and R2 have any of the values described in the specification, as well as compositions comprising a compound of formula (I) or a prodrug thereof, or a pharmaceutically acceptable salt thereof. The compounds are agonists of glycolytic enzyme phosphofructokinase-1 liver type and are useful for treating diseases associated with the activity of glycolytic enzyme phosphofructokinase-1 liver type, such as cancer, diabetes, sepsis, and septic shock.

Abstract: Disclosed herein is a system which comprises a computing device including a non-transitory computer-readable storage medium configured to store an application program; and a processor coupled to the non-transitory computer-readable storage medium and configured to control a plurality of modules to execute instructions of the application program for accessing a plurality of tasks of the system. The system further comprises a computing server system configured to: create different task queues, skill groups, and prioritizations to organize the plurality of tasks based at least upon an urgency, a complexity, or a department of each task of the plurality of the tasks, present information related to each of the plurality of tasks, queue and route the plurality of tasks, and obtain task completion information related to each of the plurality of tasks.

Abstract: Methods for detecting the presence of a pathogen infection are described. In particular, this document provides a method of detecting target nucleic acids, such as pathogen-specific RNA, in a biological sample obtained from a subject, where the method comprises using one or more toehold switch sensors and an isothermal amplification step to detect the target nucleic acid. Methods specific for detecting and identify the presence of a virus such as Zika virus are also provided.

Abstract: Methods of forming lignin prepolymers are provided. In an embodiment, such a method comprises adding an acid to an ozonized reaction mixture, the ozonized reaction mixture comprising ozonized lignin having a backbone, and aromatic monomers cleaved from a lignin, under conditions to react the cleaved aromatic monomers with the backbone of the ozonized lignin to form a lignin prepolymer. The methods may further comprise using the lignin prepolymer to form a lignin resin.

Abstract: The present invention relates to a preservative composition containing a preservative agent and a potentiator ingredient and an end-use formulation comprising the preservative composition.

Abstract: Sanitary tissue product rolls that exhibit novel combinations of physical properties, such as Moment of Inertia, Roll Density, and optionally Roll Diameter, such that the sanitary tissue product rolls meet consumers' needs, and method for making such novel sanitary tissue product rolls and marketing such novel sanitary tissue product rolls are provided.

Abstract: The present invention relates to formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar of at least 150 mg/ml, a carrier, and optionally an alkali or alkaline salt and an amino acid.

Abstract: A method and apparatus provides an enclosed pipe repair where two pipe segments extend through first and second ends of the enclosure to a volume in the enclosure housing the repair. The enclosure surrounds the repair to hopefully prevent roots from accessing the repair in many cases, and if a second problem exists, to provide access to the site of the repair through a lid in the enclosure.

Abstract: A device for efficient object detection and selective display of video frames is disclosed. A plurality of bounding boxes to visually bound one or more subjects are defined in the received video frames; each bounding box includes padding above and laterally with respect to the one or more subjects in the video frame. The device may reduce the plurality of bounding boxes by merging bounding boxes to create reduced plurality of merged bounding boxes. The device performs object detection on the reduced plurality of merged bounding boxes by searching a training database for detecting and identifying suspicious objects. The identified objects are annotated. On identifying that an object is suspicious, based on a trained database of firearms in a plurality of environments across a plurality of industries, the video frame is transmitted to a graphical user interface of a user device.

Abstract: A device may receive and store video frames in the memory. The device may define, in a video frame among the video frames, a plurality of bounding boxes to visually bound one or more subjects, each bounding box of the plurality of bounding boxes may be defined in accordance with a pre-defined aspect ratio, and each bounding box may comprise padding above and laterally with respect to the one or more subjects in the video frame. The device may reduce the plurality of bounding boxes by merging two bounding boxes among the plurality of bounding boxes to create a merged bounding box, wherein the merged bounding box may maintain the pre-defined aspect ratio and visually bounds the two bounding boxes being merged, and wherein the reduced plurality of bounding boxes is provided to an object detector.

Abstract: A device for efficient object detection and selective display of video frames is disclosed. A plurality of bounding boxes to visually bound one or more subjects are defined in the received video frames; each bounding box includes padding above and laterally with respect to the one or more subjects in the video frame. The device may reduce the plurality of bounding boxes by merging bounding boxes to create reduced plurality of merged bounding boxes. The device performs object detection on the reduced plurality of merged bounding boxes by searching a training database for detecting and identifying suspicious objects. The identified objects are annotated. On identifying that an object is suspicious, based on a trained database of firearms in a plurality of environments across a plurality of industries, the video frame is transmitted to a graphical user interface of a user device.

Abstract: According to certain embodiments, a provisioning manager comprises an interface and processing circuitry. The interface is configured to obtain provisioning data from a provisioning database. The processing circuitry is configured to prepare one or more configuration files based on the provisioning data. The configuration file(s) indicate how to provision one or more service instances. The processing circuitry is further configured to commit the configuration file(s) to one or more repositories in order to make the configuration file(s) available to at least one of the service instances. The processing circuitry is further configured to send one or more notifications indicating to one or more of the service instances that the configuration file(s) have been committed to the one or more repositories.

Abstract: According to certain embodiments, a provisioning manager comprises an interface and processing circuitry. The interface is configured to obtain provisioning data from a provisioning database. The processing circuitry is configured to prepare one or more configuration files based on the provisioning data. The configuration file(s) indicate how to provision one or more service instances. The processing circuitry is further configured to commit the configuration file(s) to one or more repositories in order to make the configuration file(s) available to at least one of the service instances. The processing circuitry is further configured to send one or more notifications indicating to one or more of the service instances that the configuration file(s) have been committed to the one or more repositories.

Abstract: A new and distinct cultivar of x Chitalpa plant named ‘NCXC1’ is disclosed, characterized by large inflorescences with vibrant purple flowers, and small tree habits. The new variety is an x Chitalpa, typically produced as an outdoor ornamental plant.

Abstract: A new and distinct cultivar of Ligustrum plant named ‘NCLJ1’ is disclosed, characterized rounded upright habit, white flowers, glossy evergreen foliage, and no apparent female fertility. The new variety is a Ligustrum, typically produced as an outdoor ornamental plant.

Abstract: A new and distinct cultivar of x Pyracomeles plant named ‘NCXP2’ is disclosed, characterized by abundant white flowers with showy red fruit. Plants have compact, rounded habits, and glossy green foliage. The new variety is an x Pyracomeles, typically produced as an outdoor ornamental plant.

Abstract: A new and distinct cultivar of Euonymus plant named ‘NCEA1’ is disclosed, characterized by plants with compact, rounded habits, good fall color, low fruit production, and greatly reduced fertility. The new cultivar is a Euonymus, suitable for ornamental garden purposes.

Abstract: A new and distinct cultivar of Rhododendron plant named ‘NCRX12’ is disclosed, characterized by a floriferous plant with a prostrate, compact habit. Single deep-pink flowers bloom in spring and rebloom in fall. The new variety is a Rhododendron, normally produced as an outdoor garden or container plant.

Abstract: A new and distinct cultivar of Ilex plant named ‘NCIC2’ is disclosed, characterized by its unique upright, narrow growth habit, and persistent, vivid yellow foliage. The new variety is an Ilex, normally produced as an outdoor garden or container plant.

Abstract: A new and distinct cultivar of Viburnum plant named ‘NCVX5’ is described, characterized by abundant white spring flowers with lustrous, evergreen foliage. Plants have upright habits and dense branching. The new cultivar is a Viburnum, typically for ornamental garden use.