Abstract: An activated polymeric carrier useful for bonding high and low molecular weight ligands has at least one unit thereof of the formula: ##STR1## wherein T represents atoms of the polymeric carrier;X is a divalent oxygen or sulfur atom, --NH--, --NHR.sup.5 --, --CONH-- or --CONR.sup.5 --, wherein R.sup.5 is lower alkyl;R is independently hydrogen, hydroxyl, lower alkyl, lower alkoxy, loweralkylthio, loweracylamino, nitro, cyano, carboxamide, loweralkylsulphonyl, loweralkoxycarbonyl, phenyl, trifluoromethyl or chloromethyl, provided that at least one R is halogen; anda is 1 or 2, b is 4-a, c is 0 or 1 and d is 2-c.

Abstract: A process for bonding a ligand to a carrier through the use of a pyrimidine derivative of the formula: ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each independently hydrogen, hydroxyl, halogen, lower alkyl, lower alkoxy, loweralkylthio, loweracylamino, nitro, cyano, carboxamido, loweralkylsulphonyl, loweralkoxycarbonyl, phenyl, trifluoromethyl or chloromethyl, the ligand or the carrier containing at least one functional group that reacts with the pyramidine derivative.

Abstract: A process for bonding a ligand to a carrier through the use of a pyrimidine derivative of the formula: ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each independently hydrogen, hydroxyl, halogen, lower alkyl, lower alkoxy, loweralkylthio, loweracylamino, nitro, cyano, carboxamido, loweralkylsulphonyl, loweralkoxycarbonyl, phenyl, trifluoromethyl or chloromethyl,The ligand or the carrier containing at least one functional group that reacts with the pyrimidine derivative.