Abstract: The present invention is directed to an artificial nucleic acid and to a polypeptide suitable for use in the treatment or prophylaxis of an infection with a flavivirus, in particular an infection with yellow fever virus or with dengue virus, or of a disorder related to such an infection. The present invention is also directed to a composition, preferably an immunogenic composition, comprising the artificial nucleic acid or the inventive polypeptide. In particular, the present invention concerns an immunogenic composition against a flavivirus, such as yellow fever virus or dengue virus. Further, the invention concerns a kit, particularly a kit of parts, comprising the artificial nucleic acid, polypeptide or (immunogenic) composition.

Abstract: The present invention provides optimized nucleic acid molecules, methods for optimization of nucleic acid molecules and uses of optimized nucleic acid molecules. A modular design principle is provided that is suitable to generate a nucleic acid, particularly mRNA, which is tailored for a respective application. The nucleic acid molecules of the present invention can be obtained by the versatile combination of multiple modules on nucleic acid level. Such nucleic acid, e.g. mRNA, can be tailored by combining one or more modules, comprising (i) a nucleic acid moiety encoding a polypeptide of interest (e.g. a protein potentially producing a therapeutic outcome) and (ii) at least one further coding or non-coding nucleic acid moiety, e.g.

Abstract: The present invention is directed to an artificial nucleic acid and to a polypeptide suitable for use in the treatment or prophylaxis of an infection with a flavivirus, in particular an infection with yellow fever virus or with dengue virus, or of a disorder related to such an infection. The present invention is also directed to a composition, preferably an immunogenic composition, comprising the artificial nucleic acid or the inventive polypeptide. In particular, the present invention concerns an immunogenic composition against a flavivirus, such as yellow fever virus or dengue virus. Further, the invention concerns a kit, particularly a kit of parts, comprising the artificial nucleic acid, polypeptide or (immunogenic) composition.

Abstract: A method for producing a partition for the interior of a commercial or transport vehicle for separating a passenger compartment from a cargo compartment. The partition is designed as a multilayer composite component made of a renewable raw material, in particular a wood-based material, which is produced by a forming process in a forming die.

Abstract: Methods can be used for producing three-dimensional objects by powder bed fusion, using inks containing superparamagnetic particles and solvents. Sintering is performed by a magnetic field having a frequency of 50 kHz to 5 GHz.

Abstract: A monofacial or bifacial crystalline solar cell, on the front face of which over the entire area a first surface passivation layer is arranged directly on the semiconductor interface and above this a first optically opaque, electrically conductive material is arranged in first lateral regions as a front face contact, and a first optically transparent, electrically conductive material is arranged exclusively in second lateral regions. The first optically transparent, electrically conductive material is electrically conductively connected to the front face contact and to a first region of the semiconductor material of the solar cell. The method provides for application of the first optically transparent, electrically conductive material only after the first optically opaque, electrically conductive material has been applied, in such a way that firing of the front face contact is avoided.

Abstract: A monofacial or bifacial crystalline solar cell, on the front face of which over the entire area a first surface passivation layer is arranged directly on the semiconductor interface and above this a first optically opaque, electrically conductive material is arranged in first lateral regions as a front face contact, and a first optically transparent, electrically conductive material is arranged exclusively in second lateral regions. The first optically transparent, electrically conductive material is electrically conductively connected to the front face contact and to a first region of the semiconductor material of the solar cell. The method provides for application of the first optically transparent, electrically conductive material only after the first optically opaque, electrically conductive material has been applied, in such a way that firing of the front face contact is avoided.

Abstract: In a composition comprising (A) a reinforcing fiber containing a carbon fiber, (B) a resin particle, and (C) a matrix resin (C), the resin particle (B) comprises a spherical resin particle having an average particle diameter of 12 to 70 ?m. In a composition comprising (A) a reinforcing fiber containing a carbon fiber, (B) a resin particle, and (C) a matrix resin, the resin particle (B) comprises (B1) a spherical small resin particle having a particle diameter less than an average fiber diameter of the reinforcing fiber (A) and (B2) a spherical large resin particle having a particle diameter not less than the average fiber diameter of the reinforcing fiber (A). The reinforcing fiber (A) may particularly comprise a carbon fiber. The resin particle (B) may particularly comprise a polyamide resin particle. The resin particle (B) may have an average particle diameter of 1 to 10 times as large as the average fiber diameter of the reinforcing fiber (A).

Abstract: According to some aspects, supports are provided for producing artificial tissue scaffolds.

Abstract: In a composition comprising (A) a reinforcing fiber containing a carbon fiber, (B) a resin particle, and (C) a matrix resin (C), the resin particle (B) comprises a spherical resin particle having an average particle diameter of 12 to 70 ?m. In a composition comprising (A) a reinforcing fiber containing a carbon fiber, (B) a resin particle, and (C) a matrix resin, the resin particle (B) comprises (B1) a spherical small resin particle having a particle diameter less than an average fiber diameter of the reinforcing fiber (A) and (B2) a spherical large resin particle having a particle diameter not less than the average fiber diameter of the reinforcing fiber (A). The reinforcing fiber (A) may particularly comprise a carbon fiber. The resin particle (B) may particularly comprise a polyamide resin particle. The resin particle (B) may have an average particle diameter of 1 to 10 times as large as the average fiber diameter of the reinforcing fiber (A).

Abstract: A multilayer plastic pipe having strong bonding between the layers has at least one layer I of a polyolefin molding composition comprising a polyolefin, at least one layer II of a polyester molding composition, and at least one layer III of an adhesion promoter containing reactive groups and located between layers I and II. The polyester molding composition of layer II comprises a polyester and one or more compounds selected from a compound having two or more carbodiimide groups, carboxylic anhydride groups, maleimide groups or oxazine groups.

Abstract: Composite comprising a polyamide-based molding composition and vulcanized fluoroelastomers. Composite articles comprising at least two subcomponents which are firmly joined to one another which comprise i) a vulcanizate and ii) a polyamide containing thermoplastic whereina) said polyamide containing thermoplastic comprises at least 30% by weight of polyamide and in said polyamide at least 30% of the end groups are amino end groups andb) said vulcanizate is produced by vulcanization of a fluororubber compound while in contact with said polyamide containing thermoplastic.

Abstract: Polyester/elastomer composites are produced by vulcanizing a polyester which contains aliphatic double bonds in the presence of a vulcanizate comprising:I. 100 parts by weight of a rubber,II. 0 to 300 parts by weight of fillers,III. 1 to 10 parts by weight of peroxidic vulcanization agent,IV. 0.5 to 4 parts by weight of vulcanization activators,V. 0 to 150 parts by weight of plasticizer andVI. 0.5 to 10 parts by weight of a silane of the formulaX--R'--Si(OR.sup.2).sub.3wherein X contains an aliphatic double bond or an epoxide group.

Abstract: A high-molecular-weight polyester is to be prepared in such a way that it is possible to very quickly and advantageously obtain even relatively small amounts having a very high molecular weight.This is achieved by preparing a polyester containing proportions of an alkene diol by continuing the polycondensation step until a viscosity number from 5 to 150 cm.sup.3 /g is reached and subsequently subjecting the polyester thus obtained to a treatment with ionizing radiation until the required viscosity number is reached.With the aid of the process of the invention it is possible to obtain high-molecular-weight polyesters having the desired property profile.

Abstract: A process for producing high molecular weight polyester is provided which allows the production of small quantities of very high molecular weight polyester in a commercially convenient manner, comprising:polycondensing an aromatic dicarboxylic acid with a mixture of an alkanediol and an alkenediol in the presence of a catalyst and in the substatial absence of oxygen, up to a viscosity number in the range from 50 to 140 cm.sup.3 /g to obtain a polyester,contacting said polyester with 0.001 to 8% by weight of an agent which forms free radicals and dissociates with a half-life of 5 seconds to 120 minutes at temperatures in the range from 130.degree. to 350.degree. C., andreacting said polyester and said agent which forms free radicals to provide the high molecular weight polyester.

Abstract: A fiber-reinforced molding composition, comprising:a) 97 to 50% by weight, relative to the sum of (a) and (b), of a mixture of 30 to 100 parts by weight of a polyphenylene ether, 0 to 70 parts by weight of a styrene polymer, 0 to 10 parts by weight of a polyoctenylene and 0.1 to 2.5 parts by weight of an .alpha.,.beta.-unsaturated carboxylic acid derivative or a precursor thereof;b) 3 to 50% by weight of carbon fibers and/or glass fibers whose surfaces bear functional groups which are capable of entering into chemical coupling reactions with the .alpha.,.beta.-unsaturated carboxylic acid derivatives; and optionallyc) dyes, pigments, plasticizers, flame retardant additives, processing auxiliaries, other customary additives or combinations thereof.

Abstract: A process for bonding a polyamide containing thermoplastic material and a rubber, comprising covulcanizing, in the presence of a vulcanization system, a thermoplastic component which contains at least 30% by wt. of an aliphatic polyamide and a rubber composition which, based on 100 parts by weight of a carboxyl group-containing rubber, contains 100-300 parts by wt. of fillers, and 1-10 parts by wt. of peroxidic vulcanizing agents.

Abstract: Components made from at least two molded materials A and B which are firmly bonded together, and in whicha) the molded material A is composed of a matrix of polyamide or of a polyamide-containing molding composition and of a continuous, fibrous reinforcement embedded therein, andb) the molded material B is the rubber obtained after peroxidic vulcanization of a rubber composition which is applied to A, the rubber composition containing the following components:i) about 100 parts by weight of a rubber having carboxyl or anhydride functional groups;ii) about 10 to 300 parts by weight of fillers; andiii) about 1 to 10 parts by weight of peroxidic vulcanizing agents.

Abstract: Direct adhesion between a body of a thermoplastic material and a rubber mass by covulcanization is achieved by bringing a rubber body constituted of the components:100 parts by weight of an EP(D)M rubber functionalized with carboxyl groups;100-300 parts by weight filler(s);1-10 parts by weight peroxide-type vulcanizing agent;0-4 parts by weight vulcanization activators; and optionally plasticizers, in contact with a body of a thermoplastic material constituted of 30-100 wt. % of a reaction product of a thermoplastic polyester and a polyisocyanate;1-50 wt. % of a reinforcing material; and0-20 wt. % of additives.

Abstract: A process for bonding a thermoplastic PPE-containing polymer and a rubber by covulcanization, comprising the steps of:heating and covulcanizing said PPE-containing polymer and said rubber, wherein said rubber comprises:(a) 100 parts by weight of a mixture comprising 100-20 wt. % of an EP(D)M rubber and 0-80 wt. % of a styrene-butadiene rubber obtained by emulsion polymerization,(b) 100-300 parts by weight of loading material,(c) 1-10 parts by weight of a peroxidic vulcanization agent, and(d) 0.5-4 parts by weight of a vulcanization activator, wherein a vulcanization bond is formed between said PPE-containing thermoplastic polymer and said rubber.