Patents by Inventor Thomas Grys

Thomas Grys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKERS FOR DETECTION AND TREATMENT ASSESSMENT OF INFECTIOUS DISEASES AND DISORDERS
    Publication number: 20250258158
    Abstract: The present invention relates to compositions and methods relating to biomarkers that can be used for detection and treatment assessment of infectious diseases or disorders, such as fungal infection, in a subject. The present invention also provides methods of diagnosing infectious diseases or disorders and distinguishing between different types of infectious diseases or disorders (e.g., fungal infection vs bacterial infection). The present invention additionally provides kits that find use in the practice of the methods of the invention.
    Type: Application
    Filed: April 22, 2025
    Publication date: August 14, 2025
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Douglas Lake, Haiwei Gu, Thomas Grys, Natalie Mitchell, Paniz Jasbi
  • BIOMARKERS FOR DETECTION AND TREATMENT ASSESSMENT OF INFECTIOUS DISEASES AND DISORDERS
    Publication number: 20210048428
    Abstract: The present invention relates to compositions and methods relating to biomarkers that can be used for detection and treatment assessment of infectious diseases or disorders, such as fungal infection, in a subject. The present invention also provides methods of diagnosing infectious diseases or disorders and distinguishing between different types of infectious diseases or disorders (e.g., fungal infection vs bacterial infection). The present invention additionally provides kits that find use in the practice of the methods of the invention.
    Type: Application
    Filed: August 13, 2020
    Publication date: February 18, 2021
    Inventors: Douglas Lake, Haiwei Gu, Thomas Grys, Natalie Mitchell, Paniz Jasbi
  • Method of reducing the viscosity of mucus
    Publication number: 20060153828
    Abstract: Disclosed is a pO157 plasmid-specified polypeptide found in E. coli EDL933 and other E. coli that binds to and cleaves C1-esterase inhibitor, and antibodies specific for the polypeptide. Also disclosed are methods employing the polypeptide for diagnosing enterohemorrhagic E. coli infection, identifying potential inhibitors of its activity, and reducing viscosity of material containing glycosylated polypeptides.
    Type: Application
    Filed: December 5, 2005
    Publication date: July 13, 2006
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Rodney Welch, Wyndham Lathem, Thomas Grys