Patents by Inventor Thomas Haimowitz

Thomas Haimowitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240018166
    Abstract: Disclosed herein are NLRP3 inflammasome inhibitors and compositions thereof. Also disclosed herein are methods including administering a therapeutically effective amount of a composition comprising at least one NLRP3 inflammasome inhibitor to a subject in need thereof.
    Type: Application
    Filed: November 23, 2021
    Publication date: January 18, 2024
    Inventors: Bin LIU, Jiangchao YAO, Thomas HAIMOWITZ, Christopher BENETATOS, Stephen M. CONDON, Steven A. BOYD
  • Publication number: 20230127898
    Abstract: Described herein are hepatitis B capsid assembly modulator compounds of formula (I) and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Application
    Filed: March 3, 2021
    Publication date: April 27, 2023
    Inventors: Jiangchao YAO, Glen COBURN, Bin LIU, Christopher BENETATOS, Steven A. BOYD, Stephen M. CONDON, Thomas HAIMOWITZ
  • Publication number: 20230107941
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Application
    Filed: December 9, 2020
    Publication date: April 6, 2023
    Inventors: Christopher J. BURNS, Glen COBURN, Bin LIU, Jiangchao YAO, Christopher BENETATOS, Steven A. BOYD, Stephen M. CONDON, Thomas HAIMOWITZ
  • Publication number: 20230062975
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Application
    Filed: September 19, 2022
    Publication date: March 2, 2023
    Inventors: Christopher J. BURNS, Glen COBURN, Bin LIU, Jiangchao YAO, Christopher BENETATOS, Steven A. BOYD, Stephen M. CONDON, Thomas HAIMOWITZ
  • Patent number: 11566001
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: January 31, 2023
    Assignee: VENATORX PHARMACEUTICALS, INC.
    Inventors: Christopher J. Burns, Glen Coburn, Bin Liu, Jiangchao Yao, Christopher Benetatos, Steven A. Boyd, Stephen M. Condon, Thomas Haimowitz
  • Publication number: 20220380341
    Abstract: A compound of formula I, or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof: wherein X1 is benzimidazolyl, substituted benzimidazolyl, azabenzimidazolyl, substituted azabenzimidazolyl, pyrazolyl, or substituted pyrazolyl; X2 is aryl, substituted aryl, arylalkyl, substituted arylalkyl, heteroaryl, substituted heteroaryl, heteroarylalkyl, substituted heteroarylalkyl, cycloalkyl, substituted cycloalkyl, (cycloalkyl)alkyl, substituted (cycloalkyl)alkyl, heterocycloalkyl, substituted heterocycloalkyl, (heterocycloalkyl)alkyl, substituted (heterocycloalkyl)alkyl, alkyl, substituted alkyl, alkoxycarbonyl, substituted alkoxycarbonyl, dialkylaminocarbonyl, substituted dialkylaminocarbonyl, (heterocycloalkyl)carbonyl, or substituted (heterocycloalkyl)carbonyl; X3 is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heterocycloalkyl, substituted heterocycloalkyl, (heterocycloalkyl)alkyl, substituted (heterocycloalkyl)alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, heter
    Type: Application
    Filed: October 17, 2019
    Publication date: December 1, 2022
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, Fox Chase Chemical Development Center, Inc.
    Inventors: Thomas Smithgall, Allen Reitz, Jay Wrobel, Colin Tice, Thomas Haimowitz, Marianne Carlsen, Marie Loughran, Hong Ye
  • Publication number: 20220298110
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Application
    Filed: October 29, 2021
    Publication date: September 22, 2022
    Inventors: Christopher J. BURNS, Glen COBURN, Bin LIU, Jiangchao YAO, Christopher BENETATOS, Steven A. BOYD, Stephen M. CONDON, Thomas HAIMOWITZ
  • Patent number: 11014881
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: May 25, 2021
    Assignee: VENATORX PHARMACEUTICALS, INC.
    Inventors: Christopher J. Burns, Glen Coburn, Bin Liu, Jiangchao Yao, Christopher Benetatos, Steven A. Boyd, Stephen M. Condon, Thomas Haimowitz
  • Publication number: 20200123105
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Application
    Filed: November 1, 2019
    Publication date: April 23, 2020
    Inventors: Christopher J. BURNS, Glen COBURN, Bin LIU, Jiangchao YAO, Christopher BENETATOS, Steven A. BOYD, Stephen M. CONDON, Thomas HAIMOWITZ
  • Patent number: 10590076
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Grant
    Filed: June 11, 2019
    Date of Patent: March 17, 2020
    Assignee: VENATORX PHARMACEUTICALS, INC.
    Inventors: Christopher J. Burns, Glen Coburn, Bin Liu, Jiangchao Yao, Christopher Benetatos, Steven A. Boyd, Stephen M. Condon, Thomas Haimowitz
  • Publication number: 20190375708
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Application
    Filed: June 11, 2019
    Publication date: December 12, 2019
    Inventors: Christopher J. BURNS, Glen COBURN, Bin LIU, Jiangchao YAO, Christopher BENETATOS, Steven A. BOYD, Stephen M. CONDON, Thomas HAIMOWITZ
  • Publication number: 20110288116
    Abstract: The present invention describes compounds of the following formula: processes for their preparation, pharmaceutical compositions containing them, and their use in therapy. The compounds of the present invention inhibit IAPs (inhibitors of apoptosis proteins) and thus are useful in the treatment of cancer, autoimmune diseases and other disorders where a defect in apoptosis is implicated.
    Type: Application
    Filed: January 15, 2009
    Publication date: November 24, 2011
    Applicant: TETRALOGIC PHARMACEUITCAL CORPORATION
    Inventors: Stephen M. Condon, Matthew G. Laporte, Yijun Deng, Susan Rippin, Yu-Hua Lee, Thomas Haimowitz