Abstract: The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided.

Abstract: The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided.

Abstract: There is provided a method of producing hydrocarbon material. A first hydrocarbon material is produced from the formation, the first hydrocarbon material including a gaseous hydrocarbon material originally in place in the formation. At least a portion of the produced gaseous hydrocarbon material is injected into the formation to increase the formation pressure. A second hydrocarbon material is produced from the formation.

Abstract: Methods of treating cancers comprising FGFR1 gene amplification are provided. In some embodiments, the methods comprise administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule. In some embodiments, the methods comprise administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule in combination with at least one additional therapeutic agent.

Abstract: There is provided a process for producing hydrocarbons from a reservoir. The process includes within the hydrocarbon reservoir, electrically heating a liquid heating fluid such that the liquid heating fluid is evaporated to produce a gaseous heating fluid, heating hydrocarbon material with the gaseous heating fluid such that the heated hydrocarbon material is mobilized and such that the gaseous heating fluid is condensed to produce a condensed heating fluid, and electrically heating at least a fraction of the condensed heating fluid such that the at least a condensed heating fluid fraction is re-evaporated, and while the evaporation, the condensing, and the re-evaporation are being effected, producing a produced fluid including at least the mobilized hydrocarbon material.

Abstract: There is provided a process for producing hydrocarbons from a reservoir. The process includes within the hydrocarbon reservoir, electrically heating a liquid heating fluid such that the liquid heating fluid is evaporated to produce a gaseous heating fluid, heating hydrocarbon material with the gaseous heating fluid such that the heated hydrocarbon material is mobilized and such that the gaseous heating fluid is condensed to produce a condensed heating fluid, and electrically heating at least a fraction of the condensed heating fluid such that the at least a condensed heating fluid fraction is re-evaporated, and while the evaporation, the condensing, and the re-evaporation are being effected, producing a produced fluid including at least the mobilized hydrocarbon material.

Abstract: The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided.

Abstract: In one aspect, there is provided a process for producing hydrocarbons from a reservoir, comprising: within the reservoir, electrically heating a liquid heating fluid such that the liquid heating fluid is evaporated to produce a gaseous heating fluid that heats the liquid hydrocarbon material within the reservoir such that the heated liquid hydrocarbon material is mobilized and such that the gaseous heating fluid is condensed to produce a condensed heating fluid, wherein the liquid heating fluid includes at least a fraction of the condensed heating fluid such that at least a fraction of the condensed heating fluid is refluxed; and producing a fluid including the mobilized hydrocarbon material; wherein the hydrocarbon reservoir is spaced apart from the earth's surface by a minimum distance of less than 75 metres.

Abstract: The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided.

Abstract: Methods of treating cancers comprising FGFR1 gene amplification are provided. In some embodiments, the methods comprise administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule. In some embodiments, the methods comprise administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule in combination with at least one additional therapeutic agent.

Abstract: A process is provided for producing hydrocarbon material from a reservoir, including: cooling at least a portion of a low permeability zone within the reservoir with effect that water, disposed within the low permeability zone, freezes and expands, with effect that one or more flow paths are formed through the low permeability zone; mobilizing hydrocarbon material within the reservoir such that the mobilized hydrocarbon material is conducted through the low permeability zone via the one or more flow paths; and after the conduction of the mobilized hydrocarbon material through the low permeability zone via the one or more flow paths, producing the mobilized hydrocarbon material.

Abstract: There is provided a method of producing hydrocarbon material. A first hydrocarbon material is produced from the formation, the first hydrocarbon material including a gaseous hydrocarbon material originally in place in the formation. At least a portion of the produced gaseous hydrocarbon material is injected into the formation to increase the formation pressure. A second hydrocarbon material is produced from the formation.

Abstract: There is provided a process for producing hydrocarbons from a reservoir. The process includes within the hydrocarbon reservoir, electrically heating a liquid heating fluid such that the liquid heating fluid is evaporated to produce a gaseous heating fluid, heating hydrocarbon-comprising material with the gaseous heating fluid such that the heated hydrocarbon-comprising material is mobilized and such that the gaseous heating fluid is condensed to produce a condensed heating fluid, and electrically heating at least a fraction of the condensed heating fluid such that the at least a condensed heating fluid fraction is re-evaporated, and while the evaporation, the condensing, and the re-evaporation are being effected, producing a produced fluid including at least the mobilized hydrocarbon-comprising material.

Abstract: Methods of treating cancers comprising FGFR1 gene amplification are provided. In some embodiments, the methods comprise administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule. In some embodiments, the methods comprise administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule in combination with at least one additional therapeutic agent.

Abstract: There is provided a process for producing hydrocarbons from a reservoir. The process includes within the hydrocarbon reservoir, electrically heating a liquid heating fluid such that the liquid heating fluid is evaporated to produce a gaseous heating fluid, heating hydrocarbon material with the gaseous heating fluid such that the heated hydrocarbon material is mobilized and such that the gaseous heating fluid is condensed to produce a condensed heating fluid, and electrically heating at least a fraction of the condensed heating fluid such that the at least a condensed heating fluid fraction is re-evaporated, and while the evaporation, the condensing, and the re-evaporation are being effected, producing a produced fluid including at least the mobilized hydrocarbon material.

Abstract: The present invention relates to prostate cancer markers, compositions comprising such markers, and methods of using such markers to induce or increase an immune response against prostate cancer. An immune response against the markers correlates with an immune response, in particular a humoral immune response, against prostate cancer cells which immune response is preferably associated with prophylaxis of prostate cancer, treatment of prostate cancer, and/or amelioration of at least one symptom associated with prostate cancer.

Abstract: The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided.

Abstract: There is provided a process for producing hydrocarbons from a reservoir. The process includes within the hydrocarbon reservoir, electrically heating a liquid heating fluid such that the liquid heating fluid is evaporated to produce a gaseous heating fluid, heating hydrocarbon-comprising material with the gaseous heating fluid such that the heated hydrocarbon-comprising material is mobilized and such that the gaseous heating fluid is condensed to produce a condensed heating fluid, and electrically heating at least a fraction of the condensed heating fluid such that the at least a condensed heating fluid fraction is re-evaporated, and while the evaporation, the condensing, and the re-evaporation are being effected, producing a produced fluid including at least the mobilized hydrocarbon-comprising material.

Abstract: The present invention relates to prostate cancer markers, compositions comprising such markers, and methods of using such markers to induce or increase an immune response against prostate cancer. An immune response against the markers correlates with an immune response, in particular a humoral immune response, against prostate cancer cells which immune response is preferably associated with prophylaxis of prostate cancer, treatment of prostate cancer, and/or amelioration of at least one symptom associated with prostate cancer.

Abstract: Methods of identifying and using FAM150A agents, FAM150B agents, and FAM150 antagonists are provided. Methods of identifying and using LTK agonists (including LTK agonist antibodies, FAM150A agents, and FAM150B agents) and FAM150 antagonists are provided. Such methods include, but are not limited to, methods of treating cancer, methods of treating immune disorders such as autoimmune diseases, and methods of treating neurodegenerative diseases.