Patents by Inventor Thomas Haws

Thomas Haws has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210349075
    Abstract: Methods are provided for the assay of secreted biomolecules using automated detection and characterization of micro-objects in a microfluidic device. The biomolecules can be secreted by cells, particularly immunological cells, such as T cells. The biomolecules being assayed can include cytokines, growth factors, and the like. Methods are also provided for assaying the cytotoxicity of a cell with respect to another, target cell. Also provided are kits and non-transitory computer-readable media in which programs are stored for causing a system comprising a computer to perform automated methods for detecting secreted biomolecules and/or cytotoxicity in a microfluidic device.
    Type: Application
    Filed: April 27, 2021
    Publication date: November 11, 2021
    Inventors: Yelena BRONEVETSKY, Annamaria MOCCIARO, Guido K. STADLER, Peter J. BEEMILLER, Natalie C. MARKS, Duane SMITH, Vincent Haw Tien PAI, Jason M. MCEWEN, Amanda L. GOODSELL, John A. TENNEY, Thomas M. VETTERLI, Hansohl E. Kim
  • Publication number: 20210272654
    Abstract: Disclosed are methods, systems, and articles of manufacture for performing a process on biological samples. An analysis of biological samples in multiple regions of interest in a microfluidic device and a timeline correlated with the analysis may be identified. One or more region-of-interest types for the multiple regions of interest may be determined; and multiple characteristics may be determined for the biological samples based at least in part upon the one or more region-of-interest types. Associated data that respectively correspond to the multiple regions of interest in a user interface for at least a portion of the biological samples in the user interface based at least in part upon the multiple identifiers and the timeline. A count of the biological samples in a region of interest may be determined based at least in part upon a class or type of data using a convolutional neural network (CNN).
    Type: Application
    Filed: May 19, 2021
    Publication date: September 2, 2021
    Applicant: BERKELEY LIGHTS, INC.
    Inventors: Darshan Thaker, Keith J. Breinlinger, Vincent Haw Tien Pai, Christoph Andreas Neyer, Thomas M. Vetterli, Hayley M. Bennett, Elisabeth Marie Walczak, Alexander Gerald Olson, Wesley Arthur Zink, John A. Tenney, Oleksandr Tokmakov, Igor Fastnacht, Yuriy Nicheporuk, Andriy Koval, Khrystyna Andres, Alona Kostenko
  • Publication number: 20190375045
    Abstract: Apparatus and methods for measuring the temperature of a substrate are disclosed. The apparatus includes a source of temperature-indicating radiation, a detector for the temperature-indicating radiation, and a decorrelator disposed in an optical path between the source of temperature-indicating radiation and the detector for the temperature-indicating radiation. The decorrelator may be a broadband amplifier and/or a mode scrambler. A broadband amplifier may be a broadband laser, Bragg grating, a fiber Bragg grating, a Raman amplifier, a Brillouin amplifier, or combinations thereof. The decorrelator is selected to emit radiation that is transmitted, at least in part, by the substrate being monitored. The source is matched to the decorrelator such that the emission spectrum of the source is within the gain bandwidth of the decorrelator, if the decorrelator is a gain-driven device.
    Type: Application
    Filed: August 26, 2019
    Publication date: December 12, 2019
    Inventors: Jiping LI, Aaron Muir HUNTER, Thomas HAW
  • Patent number: 10421151
    Abstract: Apparatus and methods for measuring the temperature of a substrate are disclosed. The apparatus includes a source of temperature-indicating radiation, a detector for the temperature-indicating radiation, and a decorrelator disposed in an optical path between the source of temperature-indicating radiation and the detector for the temperature-indicating radiation. The decorrelator may be a broadband amplifier and/or a mode scrambler. A broadband amplifier may be a broadband laser, Bragg grating, a fiber Bragg grating, a Raman amplifier, a Brillouin amplifier, or combinations thereof. The decorrelator is selected to emit radiation that is transmitted, at least in part, by the substrate being monitored. The source is matched to the decorrelator such that the emission spectrum of the source is within the gain bandwidth of the decorrelator, if the decorrelator is a gain-driven device.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: September 24, 2019
    Assignee: Applied Materials, Inc.
    Inventors: Jiping Li, Aaron Muir Hunter, Thomas Haw
  • Patent number: 9228878
    Abstract: This disclosure describes systems, methods, and apparatus for remotely monitoring an elevation, or change in elevation, of a fluid surface, such as that of molten sapphire. The remote monitoring can be performed by measuring positions of a pair of reflected laser beams off the fluid surface as detected on an imaging sensor. As the surface elevation falls, the positions of the pair of reflected laser beams move relative to each other, and this positional change can be converted into a change in the fluid surface elevation.
    Type: Grant
    Filed: March 19, 2012
    Date of Patent: January 5, 2016
    Assignee: Advanced Energy Industries, Inc.
    Inventors: Thomas Haw, Gary Kercheck
  • Publication number: 20130264316
    Abstract: Apparatus and methods for measuring the temperature of a substrate are disclosed. The apparatus includes a source of temperature-indicating radiation, a detector for the temperature-indicating radiation, and a decorrelator disposed in an optical path between the source of temperature-indicating radiation and the detector for the temperature-indicating radiation. The decorrelator may be a broadband amplifier and/or a mode scrambler. A broadband amplifier may be a broadband laser, Bragg grating, a fiber Bragg grating, a Raman amplifier, a Brillouin amplifier, or combinations thereof. The decorrelator is selected to emit radiation that is transmitted, at least in part, by the substrate being monitored. The source is matched to the decorrelator such that the emission spectrum of the source is within the gain bandwidth of the decorrelator, if the decorrelator is a gain-driven device.
    Type: Application
    Filed: March 8, 2013
    Publication date: October 10, 2013
    Inventors: Jiping Li, Aaron Muir Hunter, Thomas Haw
  • Publication number: 20130245996
    Abstract: This disclosure describes systems, methods, and apparatus for remotely monitoring an elevation, or change in elevation, of a fluid surface, such as that of molten sapphire. The remote monitoring can be performed by measuring positions of a pair of reflected laser beams off the fluid surface as detected on an imaging sensor. As the surface elevation falls, the positions of the pair of reflected laser beams move relative to each other, and this positional change can be converted into a change in the fluid surface elevation.
    Type: Application
    Filed: March 19, 2012
    Publication date: September 19, 2013
    Applicant: ADVANCED ENERGY INDUSTRIES, INC.
    Inventors: Thomas Haw, Gary Kercheck
  • Patent number: 8506161
    Abstract: This disclosure describes systems, methods, and apparatuses for making a non-contact measurement of a substrate in a plasma processing chamber that accounts for stray blackbody radiation. In particular, a photocurrent is calculated that can be attributed to the stray blackbody radiation based upon a temperature of the stray blackbody radiation, a reflectance of a target substrate, and a temperature of the substrate. Knowing the photocurrent attributable to the stray blackbody radiation, a non-contact temperature measurement can be made, and the photocurrent attributable to the stray blackbody radiation can be subtracted out to arrive at a more accurate non-contact substrate temperature measurement.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: August 13, 2013
    Assignee: Advanced Energy Industries, Inc.
    Inventor: Thomas Haw
  • Publication number: 20120327970
    Abstract: This disclosure describes systems, methods, and apparatuses for making a non-contact measurement of a substrate in a plasma processing chamber that accounts for stray blackbody radiation. In particular, a photocurrent is calculated that can be attributed to the stray blackbody radiation based upon a temperature of the stray blackbody radiation, a reflectance of a target substrate, and a temperature of the substrate. Knowing the photocurrent attributable to the stray blackbody radiation, a non-contact temperature measurement can be made, and the photocurrent attributable to the stray blackbody radiation can be subtracted out to arrive at a more accurate non-contact substrate temperature measurement.
    Type: Application
    Filed: June 21, 2011
    Publication date: December 27, 2012
    Applicant: ADVANCED ENERGY INDUSTRIES, INC.
    Inventor: Thomas Haw
  • Patent number: 8254767
    Abstract: Embodiments of the invention are directed to methods and apparatus for rapid thermal processing of a substrate over an extended temperature range, including low temperatures. Systems and methods for using an extended temperature pyrometry system employing a transmitted radiation detector system are disclosed. Systems combining transmitted radiation detector systems and emitted radiation detector systems are also described.
    Type: Grant
    Filed: August 26, 2009
    Date of Patent: August 28, 2012
    Assignee: Applied Materials, Inc.
    Inventors: Aaron M. Hunter, Jiping Li, Rajesh S. Ramanujam, Thomas Haw
  • Publication number: 20110263831
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: June 10, 2011
    Publication date: October 27, 2011
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: June KAPLOW, Thomas HAWS, Marie ROSIER, Patrice DENEFLE
  • Publication number: 20110245471
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacutre of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: June 10, 2011
    Publication date: October 6, 2011
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: June KAPLOW, Thomas HAWS, Marie ROSIER, Patrice DENEFLE
  • Patent number: 7972844
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: July 5, 2011
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Publication number: 20100054720
    Abstract: Embodiments of the invention are directed to methods and apparatus for rapid thermal processing of a substrate over an extended temperature range, including low temperatures. Systems and methods for using an extended temperature pyrometry system employing a transmitted radiation detector system are disclosed. Systems combining transmitted radiation detector systems and emitted radiation detector systems are also described.
    Type: Application
    Filed: August 26, 2009
    Publication date: March 4, 2010
    Applicant: Applied Materials, Inc.
    Inventors: Aaron M. Hunter, Jiping Li, Rajesh S. Ramanujam, Thomas Haw
  • Publication number: 20060223771
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacutre of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: February 15, 2006
    Publication date: October 5, 2006
    Applicant: Aventis Pharmaceuticals Products Inc.
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Patent number: 7041497
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: May 9, 2006
    Assignee: Aventis Pharmaceuticals Products Inc.
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Publication number: 20030170862
    Abstract: The present invention is directed to nuclear factor &kgr;B (NF&kgr;B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF&kgr;B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF&kgr;B induction in a patient, methods and compositions for lowering NF&kgr;B induction in a patient, methods for inhibiting inflammation, and methods for manufacutre of a medicament intended for the treatment and/or prevention of an NF&kgr;B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: March 30, 2001
    Publication date: September 11, 2003
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Patent number: 5275160
    Abstract: The invention features a probe for radiance dosimetry. The probe includes a tip portion containing a fluorescent dye connected to a translucent spacer element.
    Type: Grant
    Filed: January 14, 1991
    Date of Patent: January 4, 1994
    Assignee: The General Hospital Corporation
    Inventors: Lothar Lilge, Brian C. Wilson, Thomas Haw