Patents by Inventor Thomas HELLERER

Thomas HELLERER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220074860
    Abstract: Disclosed herein is a pulse-shaping method for stimulated emission depletion (STED) microscopy. The method comprises generating an optical excitation/depletion pulse with a depletion wavelength ?d; splitting the excitation/depletion pulse in time into an excitation part and a depletion part such that the excitation part and the depletion part propagate along an optical axis and are separated by a time delay ?t; creating an effective phase difference ?? between the excitation part and the depletion part; and focusing the excitation part and the depletion part of the excitation/depletion pulse onto a focus point, wherein the time delay ?t and the effective phase difference ?? are chosen such that an intensity distribution of the excitation/depletion pulse has a local maximum at the focus point at a first time and a local minimum at the focus point at a second time.
    Type: Application
    Filed: January 17, 2020
    Publication date: March 10, 2022
    Inventors: Thomas HELLERER, Christoph POLZER
  • Publication number: 20220066187
    Abstract: Disclosed herein are a method and a device for two-color confocal colocalization microscopy of a sample. The sample is labeled by a confocal imaging marker and a stimulated emission depletion (STED) imaging marker. The method comprises generating a first confocal excitation pulse with a first wavelength ?1 and a second confocal excitation pulse with a second wavelength ?2 different from the first wavelength; focusing the first and second confocal excitation pulses onto a confocal focus point; generating a STED excitation pulse with the first wavelength and a STED depletion pulse with the second wavelength; focusing the STED excitation pulse and the STED depletion pulse onto a STED focus point; and detecting light emitted from the sample at an emission wavelength ?b of the STED imaging marker and at an emission wavelength ?a of the confocal imaging marker.
    Type: Application
    Filed: January 23, 2020
    Publication date: March 3, 2022
    Inventors: Christoph POLZER, Thomas HELLERER
  • Patent number: 10355440
    Abstract: The invention relates to a method for the synthesis of electromagnetic radiation, wherein electromagnetic radiation having a spectrum comprising two or more spectral components is generated and phase setting of the electromagnetic radiation is performed. The invention proposes that the phase setting comprises phase shifting of the spectral components of the electromagnetic radiation, wherein the relative phase relationship of the spectral components is predeterminable. In addition, the invention relates to an apparatus for the synthesis of electromagnetic radiation, said apparatus comprising a pulsed laser (1), which generates a sequence of temporally equidistant light pulses, wherein the spectrum of the electromagnetic radiation of the pulsed laser (1) is the spectrum of an optical frequency comb, which is characterized by an offset frequency and a repetition rate. Furthermore, the apparatus has a phase setter (5), which effects phase setting of the electromagnetic radiation of the pulses laser (1).
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: July 16, 2019
    Assignee: TOPTICA PHOTONICS AG
    Inventors: Armin Zach, Thomas A. Puppe, Thomas Hellerer
  • Publication number: 20150303639
    Abstract: The invention relates to a method for the synthesis of electromagnetic radiation, wherein electromagnetic radiation having a spectrum comprising two or more spectral components is generated and phase setting of the electromagnetic radiation is performed. The invention proposes that the phase setting comprises phase shifting of the spectral components of the electromagnetic radiation, wherein the relative phase relationship of the spectral components is predeterminable. In addition, the invention relates to an apparatus for the synthesis of electromagnetic radiation, said apparatus comprising a pulsed laser (1), which generates a sequence of temporally equidistant light pulses, wherein the spectrum of the electromagnetic radiation of the pulsed laser (1) is the spectrum of an optical frequency comb, which is characterized by an offset frequency and a repetition rate. Furthermore, the apparatus has a phase setter (5), which effects phase setting of the electromagnetic radiation of the pulses laser (1).
    Type: Application
    Filed: December 4, 2013
    Publication date: October 22, 2015
    Applicant: TOPTICA PHOTONICS AG
    Inventors: Armin Zach, Thomas A. Puppe, Thomas Hellerer
  • Patent number: 8811435
    Abstract: The invention relates to a laser device, comprising a radiation source (1) that emits radiation having a spectrum in the form of a frequency comb having a plurality of equidistant spectral lines, and a difference frequency generator (5) that converts the radiation in such a manner that the spectrum of the converted radiation once again has the form of a frequency comb, whereby the frequencies of the spectral lines in the spectrum of the converted radiation are harmonics of a base frequency. The invention proposes that a frequency multiplier (6) follows the difference frequency generator (5) in the course of the radiation.
    Type: Grant
    Filed: October 17, 2011
    Date of Patent: August 19, 2014
    Assignee: TOPTICA Photonics AG
    Inventor: Thomas Hellerer
  • Publication number: 20120093181
    Abstract: The invention relates to a laser device, comprising a radiation source (1) that emits radiation having a spectrum in the form of a frequency comb having a plurality of equidistant spectral lines, and a difference frequency generator (5) that converts the radiation in such a manner that the spectrum of the converted radiation once again has the form of a frequency comb, whereby the frequencies of the spectral lines in the spectrum of the converted radiation are harmonics of a base frequency. The invention proposes that a frequency multiplier (6) follows the difference frequency generator (5) in the course of the radiation.
    Type: Application
    Filed: October 17, 2011
    Publication date: April 19, 2012
    Applicant: TOPTICA PHOTONICS AG
    Inventor: Thomas HELLERER