Abstract: The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

Abstract: The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

Abstract: An antenna element includes a radiator element, a plurality of feed circuits and a multiplexing interface. The radiator element can transceive radio-frequency (RF) signals. The feed circuits, which include impedance and multiplexing features, are realized on multiple feed locations of the radiating element feed slot. The multiplexing interface is electrically coupled to the plurality of feed circuits and can multiplex a number of sub-band signals associated with the feed circuits. The multiplexing interface can provide a high isolation between the feed circuits.

Abstract: A dosage-indicating topical formulation and a method of using said formulation is described. The topical formulation includes one or more bioactive substances and a topical dosage indicator. The topical dosage indicator includes one or more colored copper-containing compounds, and has a color that changes as the topical dosage indicator is absorbed into the skin. The copper-containing compound may include, for example, a copper (II) salt or a copper (I) salt; and a complexation agent containing donor atoms acting as ligands, where the donor atoms are selected from the group consisting of one or more of a nitrogen (N) atom, an oxygen (O) atom, a sulfur (S) atom. The method of using the dosage indicating topical formulation includes repeated rubbing portions of the topical formulation into the skin until the change in color indicates that the skin is saturated with the formulation.

Abstract: A device for manipulating microdroplets, the device comprising a microfluidic chip adapted to receive and manipulate microdroplets dispersed in carrier fluid flowing along pathways on a surface of the chip, wherein the microdroplets are manipulated using an optically-mediated electrowetting (oEWOD) force; characterised in that the surface of the chip comprises a coating structure configured to allow controlled attachment and/or detachment of adherent cells contained within the microdroplets by application of the oEWOD force.

Abstract: The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

Abstract: The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

Abstract: A device comprising: a first zone comprising an attachment site; a first pathway; a second pathway and a means for creating a second medium comprised of aqueous microdroplets in a carrier; a microdroplet manipulation zone comprising: a first composite wall comprised of a first transparent substrate; a first transparent conductor layer on the substrate; a photoactive layer activated by electromagnetic radiation; and a first dielectric layer on the conductor layer; a second composite wall comprised of a second substrate; a second conductor layer on the substrate; and optionally a second dielectric layer on the conductor layer; an A/C source; a source of first electromagnetic radiation; means for manipulating the points of impingement of the electromagnetic radiation on the photoactive layer; an detection zone disposed downstream of the microdroplet manipulation zone or integral therewith; and a fluorescence or Raman-scattering detection system.

Abstract: A spray device includes a bottle portion, a sleeve, and an engine. The engine includes a spring that when compressed pressurizes a chamber containing a dispensable amount of fluid from the bottle portion. The sleeve and the engine are configured to be torquable onto the bottle without compressing the spring. Rotation of the sleeve relative to the bottle by a user pressurizes a chamber containing fluid from the bottle. Auditory and/or tactile feedback is provided to the user during rotation of the sleeve thereby allowing the user to select an amount of the fluid to be dispensed. The engine includes a main spring that when compressed pressurizes a chamber containing a dispensable amount of fluid from the bottle. The spring is enclosed between a cup and a cap, which have been fused together.

Abstract: A water agency management platform provides an exchange for administering groundwater extraction rights in one or more trading-zones. The platform matches offers to trade utilization of groundwater extraction rights (GWRs), and intermediates transfers of the matched GWRs based one or more transfer rules.

Abstract: A device for manipulating microdroplets comprises a microfluidic chip adapted to receive and manipulate microdroplets dispersed in a carrier fluid flowing along pathways therethrough characterised in that chip includes regions of differing or zero microdroplet fluid flow rates. Also disclosed is an electrowetting means of transporting emulsions and components of emulsions between the different flow regions.

Abstract: A spray device includes a bottle portion, a sleeve, and an engine The engine includes a spring that when compressed pressurizes a chamber containing a dispensable amount of fluid from the bottle portion. The sleeve and the engine are configured to be torquable onto the bottle without compressing the spring. Rotation of the sleeve relative to the bottle by a user pressurizes a chamber containing fluid from the bottle. Auditory and/or tactile feedback is provided to the user during rotation of the sleeve thereby allowing the user to select an amount of the fluid to be dispensed. The engine includes a main spring that when compressed pressurizes a chamber containing a dispensable amount of fluid from the bottle. The spring is enclosed between a cup and a cap, which have been fused together.

Abstract: A device comprising: a first zone comprising an attachment site; a first pathway; a second pathway and a means for creating a second medium comprised of aqueous microdroplets in a carrier; a microdroplet manipulation zone comprising: a first composite wall comprised of a first transparent substrate; a first transparent conductor layer on the substrate; a photoactive layer activated by electromagnetic radiation; and a first dielectric layer on the conductor layer; a second composite wall comprised of a second substrate; a second conductor layer on the substrate; and optionally a second dielectric layer on the conductor layer; an A/C source; a source of first electromagnetic radiation; means for manipulating the points of impingement of the electromagnetic radiation on the photoactive layer; an detection zone disposed downstream of the microdroplet manipulation zone or integral therewith; and a fluorescence or Raman-scattering detection system.

Abstract: Systems, methods, and devices for forming an array of emulsions. An exemplary device comprises a frame and at least one or a plurality of separate microfluidic modules mounted to the frame and each configured to form an array of emulsions. In some embodiments, each module may be mounted by snap-fit attachment. The device also may include the same sealing member bonded to a top side of each module and hermetically sealing each of the modules. Another exemplary microfluidic device for forming an array of emulsions comprises a stack of layers bonded together. The stack may comprise a port layer forming a plurality of ports. Each port may have a top rim formed by a protrusion that encircles the central axis of the port. The rims may be coplanar with one another to facilitate bonding of a sealing member to each rim.

Abstract: The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

Abstract: The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

Abstract: Disclosed herein are occipital plates that include a fixation plate portion and at least two extensions integrally connected to the fixation plate portion and extending away from the fixation plate portion. The fixation plate portion has a plurality of through-holes for receiving bone screws that secure the occipital plate to a patient's skull or, specifically, the occiput. Each extension includes a slot for removably receiving a rod connector or a rod-to-rod connector, the slots having an entry area or portion for receiving a connector and a holding area or portion for maintaining the connector in the slot.

Abstract: An electronic newsletter distribution system useful in association with a water agency management platform provides information exchange for administering groundwater extraction rights in one or more trading-zones. The platform matches offers to trade utilization of groundwater extraction rights (GWRs), and intermediates transfers of the matched GWRs based one or more transfer rules. The system also facilitates trading of “sell order” and “buy order” in response to the water pricing and water offering information.

Abstract: Systems and methods are provided for wide scan phased array fed reflector systems using ring-focus optics to significantly improve the scan volume of such systems. The subject system includes a reflector having a focal plane and a parabolic curvature configured to receive electromagnetic radiation having a first gain and provide reflected electromagnetic radiation having a second gain greater than the first gain that collimates into a focal ring. The subject system includes a feed array having feed elements positioned about the focal ring, in which each feed element is configured to receive the reflected electromagnetic radiation from the reflector and collimate the reflected electromagnetic radiation into a scanned beam for scanning an annular region. In some aspects, the feed array is centered on the focal ring such that at least one feed element overlaps with the focal ring and remaining feed elements are non-overlapping with the focal ring.

Abstract: Injection device (2) comprising a housing (3), a syringe cradle (12) for removably receiving a syringe (1) having a needle (7), a container (10) with a flange (11), a plunger (9) and a removable needle cap (8) in the housing, and a system for performing automated injection comprising: —a cap actuation mechanism (4) for gripping, storing and retrieving the needle cap, —a syringe actuation mechanism (5) for moving the syringe in an injection direction (Id) from a position where the needle is inside the housing to an injection position where the needle projects out of a needle port of the housing on a skin contact face of the housing, and —a plunger actuation mechanism (6) for advancing the plunger for administration of the liquid drug.