Patents by Inventor Thomas Herget

Thomas Herget has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF PERFORMING AN ASSAY
    Publication number: 20130122517
    Abstract: The present invention relates to a method and kit for performing assays like immunoassays. The assays are performed by using two different types of magnetic beads.
    Type: Application
    Filed: June 30, 2011
    Publication date: May 16, 2013
    Applicant: MERCK PATENT GMBH
    Inventors: Tanja Henzler, Karl Holschuh, Johann Bauer, Thomas Herget, Michael Hartmann, Oliver Poetz, Thomas Joos
  • Pharmaceutically active 4,6-disubstituted aminopyrimidine derivatives as modulators of protein kinases
    Patent number: 8084457
    Abstract: The present invention relates to 4,6-disubstituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, and pharmaceutical compositions containing at least one of said 4,6-di substituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: December 27, 2011
    Assignees: Lead Discovery Center GmbH, Bayer Pharma AG
    Inventors: Axel Choidas, Alexander Backes, Matt Cotten, Ola Engkvist, Beatrice Felber, Achim Freisleben, Klaus Godl, Zoltán Greff, Peter Habenberger, Doris Hafenbradl, Christian Hartung, Thomas Herget, Edmund Hoppe, Bert Klebl, Andrea Missio, Gerhard Müller, Wilfried Schwab, Birgit Zech, Jose Bravo, John Harris, Joelle Le, Jackie Macritchie, Vladimir Savic, Brad Sherborne, Don Simpson
  • METHOD OF LONG TERM STORAGE OF SUBSTRATE-COUPLED BEADS
    Publication number: 20110027126
    Abstract: The present invention relates to a method for a long term storage of substrate-coupled beads prepared for biological reactions, preferably enzymatic reactions. Suitable beads for this method may be inorganic or organic. Preferably polystyrene beads are used for this method.
    Type: Application
    Filed: March 13, 2009
    Publication date: February 3, 2011
    Applicant: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Tanja Henzler, Thomas Herget
  • Pyrazine Derivatives As Effective Compounds Against Infectious Diseases
    Publication number: 20080194574
    Abstract: The present invention relates to pyrazine derivatives according to the general formula (I) and pharmaceutically acceptable salts thereof and their use as pharmaceutical compounds as well as the use of these compounds for the preparation of a pharmaceutical composition for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases, stroke and especially for the treatment of herpesviral induced infections, including opportunistic infections as well as infections and diseases caused by human cytomegalovirus (HCMV).
    Type: Application
    Filed: December 16, 2004
    Publication date: August 14, 2008
    Applicant: AXXIMA PHARMACEUTICALS AG
    Inventors: Jan Eike Eikhoff, Mark Richard Ashton, Stephen Martin Courtney, Christopher John Yarnold, Maurizio Varrone, Pui Leng Loke, Thomas Herget, Wilfried Schwab, Doris Hafenbradl
  • Therapeutic targets for treatment of HCV infections, methods of treating HCV infections and compounds useful therefor
    Patent number: 7341717
    Abstract: The present invention relates to the human cellular protein glutathione peroxidase-gastrointestinal as a target for medical intervention against Hepatitis C virus (HCV) infections. Furthermore, the present invention relates to a method for the detection of compounds useful for prophylaxis and/or treatment of Hepatitis C virus infections and a method for detecting Hepatitis C virus infections in an individual or in cells. Also compositions, compounds, nucleic acid molecules (such as aptamers), mono- or polyclonal antibodies are disclosed which are effective for the treatment of HCV infections, and methods for prophylaxis and/or treatment of Hepatitis C virus infections or for the regulation of Hepatitis C virus production are disclosed.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: March 11, 2008
    Assignee: GPC Biotech AG
    Inventors: Thomas Herget, Matthew Cotten, Sabine Obert, Bert Klebl
  • Pharmaceutically active 4,6-disubstituted aminopyrimidine derivatives as modulators of protein kinases
    Publication number: 20070191344
    Abstract: The present invention relates to 4,6-disubstituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, and pharmaceutical compositions containing at least one of said 4,6-di substituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: September 15, 2004
    Publication date: August 16, 2007
    Inventors: Axel Choidas, Alexander Backes, Matt Cotten, Ola Engkvist, Beatrice Felber, Achim Freisleben, Klaus Godl, Zoltan Greff, Peter Habenberger, Doris Hafenbradl, Christian Hartung, Thomas Herget, Edmund Hoppe, Bert Klebl, Andrea Missio, Gerhard Muller, Wilfried Schwab, Birgit Zech, Jose Bravo, John Harris, Joelle Le, Jackie Macritchie, Vladimir Savic, Brad Sherborne, Don Simpson
  • Quinazoline derivatives for the treatment of herpesviral infections
    Publication number: 20070123537
    Abstract: The present invention relates to phenyl-quinazolinyl-amine derivatives and pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising at least one of these derivatives and/or pharmaceutically salts thereof, as well as the use of these derivatives for the prophylaxis and/or treatment of herpesviral induced infections, including opportunistic infections, especially for the prophylaxis and/or treatment of infections and diseases induced by HCMV.
    Type: Application
    Filed: October 5, 2004
    Publication date: May 31, 2007
    Applicant: GPC Biotech AG
    Inventor: Thomas Herget
  • Formulations useful against hepatitis C virus infections
    Publication number: 20060151574
    Abstract: The present invention relates generally to chemical compounds and substances which are effective against Hepatitis C virus (HCV) infections. Moreover, the present invention relates to compositions comprising said compounds and/or substances, to methods for preventing HCV infections as well use of the compounds and/or substances for the preparation of compositions useful for the prophylaxis and/or treatment of HCV infections.
    Type: Application
    Filed: December 1, 2003
    Publication date: July 13, 2006
    Applicant: GPC Biotech AG
    Inventors: Thomas Herget, Bert Klebl
  • Therapeutic targets for treatment of HCV infections, methods of treating HCV infections and compounds useful therefor
    Publication number: 20040152073
    Abstract: The present invention relates to the human cellular protein glutathione peroxidase-gastrointestinal as a target for medical intervention against Hepatitis C virus (HCV) infections. Furthermore, the present invention relates to a method for the detection of compounds useful for prophylaxis and/or treatment of Hepatitis C virus infections and a method for detecting Hepatitis C virus infections in an individual or in cells. Also compositions, compounds, nucleic acid molecules (such as aptamers), mono- or polyclonal antibodies are disclosed which are effective for the treatment of HCV infections, and methods for prophylaxis and/or treatment of Hepatitis C virus infections or for the regulation of Hepatitis C virus production are disclosed.
    Type: Application
    Filed: November 26, 2003
    Publication date: August 5, 2004
    Inventors: Thomas Herget, Matthew Cotten, Sabine Obert, Bert Klebl
  • Human cellular protein gastrointestinal glutathione peroxidase as target for medical intervention against hepatitis C virus infections
    Publication number: 20030180719
    Abstract: The present invention relates to the human cellular protein glutathione peroxidase-gastrointestinal as a target for medical intervention against Hepatitis C virus (HCV) infections. Furthermore, the present invention relates to a method for the detection of compounds useful for prophylaxis and/or treatment of Hepatitis C virus infections and a method for detecting Hepatitis C virus infections in an individual or in cells. Also compositions, compounds, nucleic acid molecules (such as aptamers), mono- or polyclonal antibodies are disclosed which are effective for the treatment of HCV infections, and methods for prophylaxis and/or treatment of Hepatitis C virus infections or for the regulation of Hepatitis C virus production are disclosed.
    Type: Application
    Filed: January 14, 2003
    Publication date: September 25, 2003
    Inventors: Thomas Herget, Matthew Cotten, Sabine Obert
  • Resistance genes
    Patent number: 6262338
    Abstract: The present invention relates to DNA isolated from Arachis hypogaea which encodes or hybridizes to DNA which encodes a protein that repels pests. Such DNA is useful in the transformation of vectors, host organisms and plants and for the production of plants which exhibit an increased resistance to pests.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: July 17, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Peter Schreier, Thomas Herget, Jeff Schell