Patents by Inventor Thomas Himmler

Thomas Himmler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing 2,6-dialkylphenylacetic acids
    Patent number: 11691938
    Abstract: The invention relates to a multi-stage process for preparing 2,6-dialkylphenylacetic acids of the general formula (I) by reacting 2,6-dialkylbromobenzenes with (1) magnesium, (2) a formamide, (3) an acid, (4) hydrogenation of the benzaldehyde obtained, (5) activation of the benzyl alcohol obtained, (6) cyanation of the activated benzyl alcohol and (7) hydrolysis of the nitrile obtained.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: July 4, 2023
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Himmler, Dirk Brohm, Wahed Ahmed Moradi
  • PROCESS OF PREPARING 2-(PHENYLIMINO)-3-ALKYL-1,3-THIAZOLIDIN-4-ONES
    Publication number: 20230105595
    Abstract: The present invention relates to a method for preparing 2-(phenylimino)-3-alkyl-1,3-thiazolidin-4-ones of the general formula (I) in which Y1, Y2, R1, R2 and R3 are as defined in the description.
    Type: Application
    Filed: February 15, 2021
    Publication date: April 6, 2023
    Inventors: Thomas HIMMLER, Sergii PAZENOK, Julia Johanna HAHN, Klaus-Ulrich SCHIFFER
  • Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives
    Patent number: 11505544
    Abstract: The present invention relates to a new process for preparing quinoline compounds of the general formula (II): in which Q, A, R4, R3 and R3?, are as defined herein, as well as to the intermediate compounds of said new process.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: November 22, 2022
    Assignee: Bayer Animal Health GMBH
    Inventors: Florian Erver, Frank Memmel, Thomas Himmler, Andreas Karl Steib, Marc Nowakowski
  • PROCESS OF PREPARING 1,1'-DISULFANDIYLBIS(4-FLUORO-2-METHYL-5-NITROBENZOL)
    Publication number: 20220348538
    Abstract: The present invention relates to a process for preparing 1,1?-disulfanediylbis(4-fluoro-2-methyl-5-nitrobenzene) which serves as an intermediate for the preparation of insecticidally, acaricidally and nematicidally active phenyl sulfoxides.
    Type: Application
    Filed: October 13, 2020
    Publication date: November 3, 2022
    Inventor: Thomas HIMMLER
  • PROCESS OF PREPARING 2-(PHENYLIMINO)-1,3-THIAZOLIDIN-4-ONES
    Publication number: 20220315545
    Abstract: The present invention relates to a method for preparing 2-(phenylimino)-1,3-thiazolidin-4-ones of the general formula (I). in which Y1, Y2, R1, R2 and R3 are as defined in the description.
    Type: Application
    Filed: July 8, 2020
    Publication date: October 6, 2022
    Inventors: Thomas HIMMLER, Julia Johanna HAHN
  • PROCESS OF PREPARING 2-(PHENYLIMINO)-3-ALKYL-1,3-THIAZOLIDIN-4-ONES
    Publication number: 20220298126
    Abstract: The present invention relates to a novel method for preparing 2-(phenylimino)-3-alkyl-1,3-thiazolidin-4-ones of the general formula (I) in which Y1, Y2, R1, R2 and R3 are as defined in the description.
    Type: Application
    Filed: August 13, 2020
    Publication date: September 22, 2022
    Inventors: Thomas HIMMLER, Julia Johanna HAHN, Sergii PAZENOK, Silvia CEREZO-GALVEZ, Bernd ALIG
  • PROCESS FOR PREPARING ESTERS OF N-ACYLATED AMINO ACIDS WITH ACID-LABILE KETO PROTECTIVE GROUP FUNCTIONS
    Publication number: 20220267291
    Abstract: The present invention relates to a novel process for the esterification of N-acylated amino acids which contain an acid-labile keto protective group under alkaline conditions without using a polar aprotic solvent, in which the N-acylated amino acid with acid-labile keto protective group prepared in situ is esterified using an alkyl halide or a mono- or dialkyl ester of sulfuric acid.
    Type: Application
    Filed: May 13, 2022
    Publication date: August 25, 2022
    Inventors: Albert SCHNATTERER, Michael DOCKNER, Peter BRUECHNER, Thomas HIMMLER
  • PROCESS OF PREPARING 2-(PHENYLIMINO)-1,3-THIAZOLIDIN-4-ONES
    Publication number: 20220251053
    Abstract: The present invention relates to a method for preparing 2-(phenylimino)-1,3-thiazolidin-4-ones of the general formula (I). in which Y1, Y2, R1, R2 and R3 are as defined in the description.
    Type: Application
    Filed: July 8, 2020
    Publication date: August 11, 2022
    Inventors: Thomas HIMMLER, Julia Johanna HAHN
  • Process for preparing esters of N-acylated amino acids with acid-labile keto protective group functions
    Patent number: 11384061
    Abstract: The present invention relates to a novel process for the esterification of N-acylated amino acids which contain an acid-labile keto protective group under alkaline conditions without using a polar aprotic solvent, in which the N-acylated amino acid with acid-labile keto protective group prepared in situ is esterified using an alkyl halide or a mono- or dialkyl ester of sulfuric acid.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: July 12, 2022
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Albert Schnatterer, Michael Dockner, Peter Bruechner, Thomas Himmler
  • Process for preparing spiroketal-substituted cyclic ketoenols
    Patent number: 11220511
    Abstract: The invention relates to a novel process for preparing spiroketal-substituted cyclic ketoenols which can be used as insecticides, acaricides or herbicides. The present invention also relates to novel intermediates for the preparation of spiroketal-substituted cyclic ketoenols.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: January 11, 2022
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Thomas Himmler, Julia Johanna Hahn, Joachim Crede
  • PROCESS FOR PREPARING 2,6-DIALKYLPHENYLACETIC ACIDS
    Publication number: 20210403406
    Abstract: The invention relates to a multi-stage process for preparing 2,6-dialkylphenylacetic acids of the general formula (I) by reacting 2,6-dialkylbromobenzenes with (1) magnesium, (2) a formamide, (3) an acid, (4) hydrogenation of the benzaldehyde obtained, (5) activation of the benzyl alcohol obtained, (6) cyanation of the activated benzyl alcohol and (7) hydrolysis of the nitrile obtained.
    Type: Application
    Filed: April 3, 2019
    Publication date: December 30, 2021
    Inventors: Thomas HIMMLER, Dirk BROHM, Wahed Ahmed MORADI
  • PROCESS FOR PREPARING ESTERS OF N-ACYLATED AMINO ACIDS WITH ACID-LABILE KETO PROTECTIVE GROUP FUNCTIONS
    Publication number: 20210139450
    Abstract: The present invention relates to a novel process for the esterification of N-acylated amino acids which contain an acid-labile keto protective group under alkaline conditions without using a polar aprotic solvent, in which the N-acylated amino acid with acid-labile keto protective group prepared in situ is esterified using an alkyl halide or a mono- or dialkyl ester of sulfuric acid.
    Type: Application
    Filed: April 15, 2019
    Publication date: May 13, 2021
    Inventors: Albert SCHNATTERER, Michael DOCKNER, Peter BRUECHNER, Thomas HIMMLER
  • PROCESS FOR PREPARING SUBSTITUTED CYCLOHEXANE AMINO ACID ESTERS AND SPIROKETAL-SUBSTITUTED CYCLIC KETO-ENOLS
    Publication number: 20210032262
    Abstract: The present invention relates to a novel process for preparing substituted cyclohexane amino acid esters and spiroketal-substituted cyclic keto-enols, and to novel intermediates or starting compounds that are passed through or used in the process according to the invention.
    Type: Application
    Filed: April 3, 2019
    Publication date: February 4, 2021
    Inventors: Thomas HIMMLER, Peter BRUECHNER, Werner LINDNER, Julia Johanna HAHN, Wahed Ahmed MORADI, Reiner FISCHER, Michael DOCKNER
  • PROCESS FOR PREPARING ANTIHELMINTIC 4-AMINO-QUINOLINE-3-CARBOXAMIDE DERIVATIVES
    Publication number: 20200308153
    Abstract: The present invention relates to a new process for preparing quinoline compounds of the general formula (II): in which Q, A, R4, R3 and R3?, are as defined herein, as well as to the intermediate compounds of said new process.
    Type: Application
    Filed: December 14, 2018
    Publication date: October 1, 2020
    Applicant: Bayer Animal Health GMBH
    Inventors: Florian ERVER, Frank MEMMEL, Thomas HIMMLER, Andreas Karl STEIB, Marc NOWAKOWSKI
  • Catalytic hydrogenation of nitriles
    Patent number: 10766859
    Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of Raney catalysts, in particular Raney nickel or cobalt.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: September 8, 2020
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Wahed Ahmed Moradi, Thomas Himmler, Thomas Norbert Mueller
  • Process for preparing 3-chloro-2-vinylphenylsulfonates
    Patent number: 10618872
    Abstract: The present invention relates to a new process for preparing 3-chloro-2-vinylphenylsulfonate derivatives.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: April 14, 2020
    Assignee: Bayer CropScience Aktiengesellschaft
    Inventors: Peter Brüchner, Thomas Himmler, Sergii Pazenok, Mark James Ford
  • CATALYTIC HYDROGENATION OF NITRILES
    Publication number: 20200039936
    Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of Raney catalysts, in particular Raney nickel or cobalt.
    Type: Application
    Filed: December 18, 2017
    Publication date: February 6, 2020
    Inventors: Wahed Ahmed MORADI, Thomas HIMMLER, Thomas Norbert MUELLER
  • Process for preparing substituted 2-arylethanols
    Patent number: 10519085
    Abstract: The invention relates to a process for preparing substituted 2-arylethanols of the formula (I) by reacting Grignard compounds of the formula (II) in the presence of a copper compound with ethylene oxide. Moreover, the invention relates to novel substituted 2-arylethanols of the formula (I).
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: December 31, 2019
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Thomas Himmler, Peter Brüchner
  • Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids
    Patent number: 10435352
    Abstract: A process for preparing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids of the formula (I) is described. Here, the substituents are radicals such as alkyl and substituted phenyl.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: October 8, 2019
    Assignee: Bayer CropScience Aktiengesellschaft
    Inventors: Christian Funke, Thomas Himmler, Sergii Pazenok, Christoph Schotes, Matthias Beller, Thomas Schareina, Alexander Zapf
  • Catalytic hydrogenation of nitriles
    Patent number: 10414730
    Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of metal catalysts, in particular palladium catalysts.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: September 17, 2019
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Wahed Ahmed Moradi, Thomas Himmler, Thomas Norbert Müller, Albert Schnatterer, Günter Schlegel