Abstract: The present invention relates to the use of an antibody or an antigen-binding fragment thereof with specific binding activity for human interleukin-4 for the prevention and/or treatment of cancer.

Abstract: The invention relates to compounds of the formula I and the tautomeric forms, possible enantiomeric and diasteromeric forms thereof, and prodrugs thereof, and use thereof as PARP inhibitors.

Abstract: A method serves the purpose of introducing fuel and/or thermal energy into a gas stream flowing to a catalytic reactor. The gas stream flows in part through an exterior chamber and in part through an interior chamber, which is at least partially open in the flow direction and to which fuel is supplied. The partial streams are re-united after flowing through the two chambers and are fed to the catalytic reactor. In a starting phase of the still cold catalytic reactor, the fuel is burned in the interior chamber. During conventional normal operating modes of the warm catalytic reactor, the fuel is vaporized in the interior chamber. In a suitable device, the exterior chamber and the interior chamber are designed as two tube elements that are inserted into one another.

Abstract: Compounds of the formula I or II and their tautomeric forms, possible enantiomeric and diastereomeric forms, possible cistrans isomers on the rings in A and prodrugs thereof, pharmaceutical compositions containing these compounds and methods of treating neurodegenerative diseases or neuronal damage with these compounds.

Abstract: The present invention relates to novel benzimidazoles, their preparation and their use as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30) for producing drugs.

Abstract: The invention relates to compounds of formula (I), wherein; either A1 or A2 represents CONH2, and the other radical A2 or A1 represents hydrogen, chlorine, fluorine, bromine, iodine C1-C6 alkyl, OH, nitro, CF3, CN, NR11R12, NH—CO—R13, O—C1-C4 alkyl; X1 can represent N and C—R2; X2, independent of X1, can represent N and C—R2; R2 can represent hydrogen, C1-C6 alkyl, C1-C4 alkyl-phenyl, phenyl; B can represent an unsaturated, saturated or partially unsaturated monocyclic, bicyclic or tricyclic ring having a maximum of 15 carbon atoms, an unsaturated, saturated or partially unsaturated monocyclic, bicyclic or tricyclic ring having a maximum of 14 carbon atoms and 0 to 5 nitrogen atoms, 0 to 2 oxygen atoms or 0 to 2 sulfur atoms, which can each still be substituted with an R4 and a maximum of 3 of the same or different radicals R5, and; R1, R4, R5, R11-R13 have the meanings as cited in claim No. 1.

Abstract: A method serves the purpose of introducing fuel and/or thermal energy into a gas stream flowing to a catalytic reactor. The gas stream flows in part through an exterior chamber and in part through an interior chamber, which is at least partially open in the flow direction and to which fuel is supplied. The partial streams are re-united after flowing through the two chambers and are fed to the catalytic reactor. In a starting phase of the still cold catalytic reactor, the fuel is burned in the interior chamber. During conventional normal operating modes of the warm catalytic reactor, the fuel is vaporized in the interior chamber. In a suitable device, the exterior chamber and the interior chamber are designed as two tube elements that are inserted into one another.