Patents by Inventor Thomas Hoffman
Thomas Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240147996Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: ApplicationFiled: November 8, 2023Publication date: May 9, 2024Inventors: Yunxing C. CUI, Thomas HOFFMAN, Ning ZHOU, Stephen N. NOVAK, Julissa COLON, Dawn M. PARKHURST, Sandra G. TOLEDO, Terry R. WRIGHT, Sean M. RUSSELL, Bruce HELD, Vaithilingam SEKAR
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Patent number: 11925381Abstract: In accordance with an aspect of the present disclosure, a tissue extraction device may include a bag having an interior and a plurality of cutters elements extending along an interior surface of the bag. The cutters can be offset to facilitate collapsing of the bag prior to introducing the bag into a patient.Type: GrantFiled: March 31, 2022Date of Patent: March 12, 2024Assignee: Freyja Healthcare, LLCInventors: James Bleck, John Aho, Thomas Eagan, Jonathan Towle, Mark Hoffman
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Patent number: 11819022Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: GrantFiled: August 29, 2022Date of Patent: November 21, 2023Assignees: Dow AgroSciences LLC, M.S. Technologies, L.L.C.Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
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Publication number: 20230143169Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: ApplicationFiled: August 29, 2022Publication date: May 11, 2023Inventors: Yunxing C. CUI, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhursl, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
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Publication number: 20230056359Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: ApplicationFiled: July 28, 2022Publication date: February 23, 2023Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
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Publication number: 20220409148Abstract: The invention relates to a computer-assisted tomography (CT) system having the following features: a) at least one X-ray source, b) at least one patient couch for supporting a patient, c) at least one collimator in the ray path of the X-rays from the X-ray source through the patient, wherein a targeted X-ray from among the total X-ray radiation of the X-ray source is radiated by the collimator onto the patient, d) at least one X-ray detector, provided permanently or at least temporarily in the ray path of the targeted X-ray radiated by the collimator through the patient, e) at least one automatically actuable drive mechanism, using which the collimator can be moved with respect to the radiation direction of the targeted X-ray passing through the collimator, relative to the patient and/or to the X-ray detector, f) at least one electronic control device that is configured to automatically actuate the drive mechanism.Type: ApplicationFiled: December 16, 2020Publication date: December 29, 2022Inventors: Georg ROSE, Thomas HOFFMAN, Mathias LEOPOLD, Oliver Großer, Maciej PECH
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Patent number: 11425906Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: GrantFiled: April 7, 2021Date of Patent: August 30, 2022Assignees: Dow AgroSciences LLC, M.S. Technologies, L.L.C.Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
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Publication number: 20220256990Abstract: A hair scrunchie is described. The hair scrunchie may include a covering that includes a head and feet or other lower appendages located on opposite sides of an opening. The hair scrunchie may be movable between an expanded configuration and a collapsed configuration and may include a lock to maintain the hair scrunchie in a configuration until actuated by the user.Type: ApplicationFiled: February 16, 2021Publication date: August 18, 2022Inventors: Thomas Hoffman Brown, Michael Edward Tant, JR., Jenna Harlander
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Publication number: 20210323995Abstract: The present invention relates to isolithocholic acid (3ß-hydroxy-5ß-cholan-24-oic acid, iso-LCA) and isoallolithocholic acid (3ß-hydroxy-5?-cholan-24-oic acid) and their deuterated analogs for preventing or treating Clostridium difficile-associated disease in a mammalian subject.Type: ApplicationFiled: August 8, 2019Publication date: October 21, 2021Applicant: PHENEX PHARMACEUTICALS AGInventors: Christian Gege, Manfred Birkel, Thomas Hoffman
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Publication number: 20210267198Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: ApplicationFiled: April 7, 2021Publication date: September 2, 2021Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
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Patent number: 10973229Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: GrantFiled: June 7, 2019Date of Patent: April 13, 2021Assignees: Dow Agrosciences LLC, M.S. Technologies, L.L.C.Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
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Publication number: 20200093129Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: ApplicationFiled: June 7, 2019Publication date: March 26, 2020Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
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Patent number: 10595456Abstract: A discharge device includes a plurality of material conveying components, an adjustable shear ledge, and an adjustable shroud to convey materials from a container of a material spreader out onto an open area. The adjustable shear ledge includes at least one longitudinal mounting member such that the adjustable shear ledge may be translated towards or away from the plurality of material conveying components to maintain a predetermined gap distance. The adjustable shroud may also be pivotably connected to the adjustable shear ledge such that the adjustable shroud can be pivoted towards or away from the plurality of material conveying components. The adjustable shear ledge and the adjustable shroud may be moved accordingly to maintain a preferred gap distance and to maintain concentricity with a swing of the material conveying components in order to reduce wear on components and promote spread performance of the material spreader.Type: GrantFiled: November 10, 2017Date of Patent: March 24, 2020Assignee: KUHN NORTH AMERICA, INC.Inventors: Thomas Hoffman, Todd Gibson, Patrick Henry, Claude McFarlane
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Patent number: 10455834Abstract: Soybean event 9582.816.15.1 comprises genes encoding Cry1 F, Cry1 Ac (synpro), and PAT, affording insect resistance and herbicide tolerance to soybean crops containing the event, and enabling methods for crop protection and protection of stored products. Embodiments of the present disclosure relate to a new insect resistant and herbicide tolerant transgenic soybean transformation event, designated soybean event pDAB9582.816.15.1, comprising cry1 F v3 (cry1 F), cry1 Ac synpro (cry1 Ac) and pat v6 (pat), as described herein, inserted into a specific site within the genome of a soybean cell. Representative soybean seed has been deposited with American Type Culture Collection (ATCC) with the Accession No. ATCC Deposit No. PTA-12588. The DNA of soybean plants containing this event includes the junction/flanking sequences described herein that characterize the location of the inserted DNA within the soybean genome.Type: GrantFiled: June 25, 2013Date of Patent: October 29, 2019Assignee: Dow AgroSciences LLCInventors: Nathan Bard, Gregory A. Bradfisch, Yunxing Cory Cui, James E. Dripps, Thomas Hoffman, Dayakar Pareddy, Dawn M. Parkhurst, Sandra G. Toledo, Barry Wiggins, Ning Zhou, Aaron T. Woosley
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Patent number: 10400250Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.Type: GrantFiled: January 5, 2017Date of Patent: September 3, 2019Assignees: Dow AgroSciences LLC, MS Technologies, L.L.C.Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
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Patent number: 10207827Abstract: A habitation module that provides an artificial gravity environment. In one embodiment, the habitation module includes a rotating structure that rotates about an axis in relation to a stationary structure. The rotating structure includes a first gravity chamber that projects radially from the rotating structure, and a second gravity chamber that projects radially from the rotating structure in an opposite direction than the first gravity chamber. The first gravity chamber and the second gravity chamber are each comprised of a plurality of ring members that form side walls of the first gravity chamber and the second gravity chamber. The ring members are concentric so that the side walls of the first gravity chamber and the second gravity chamber radially extend and radially contract in upon themselves.Type: GrantFiled: June 26, 2017Date of Patent: February 19, 2019Assignee: The Boeing CompanyInventors: Raju Dharmaraj, Thomas Hoffman, Craig Stanton, Patrick A. Swartzell
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Publication number: 20180370661Abstract: A habitation module that provides an artificial gravity environment. In one embodiment, the habitation module includes a rotating structure that rotates about an axis in relation to a stationary structure. The rotating structure includes a first gravity chamber that projects radially from the rotating structure, and a second gravity chamber that projects radially from the rotating structure in an opposite direction than the first gravity chamber. The first gravity chamber and the second gravity chamber are each comprised of a plurality of ring members that form side walls of the first gravity chamber and the second gravity chamber. The ring members are concentric so that the side walls of the first gravity chamber and the second gravity chamber radially extend and radially contract in upon themselves.Type: ApplicationFiled: June 26, 2017Publication date: December 27, 2018Inventors: Raju Dharmaraj, Thomas Hoffman, Craig Stanton, Patrick A. Swartzell
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Publication number: 20180265483Abstract: Compounds of the formula (I) wherein, the substituents are as defined in claim 1, useful as a pesticides, especially as fungicides.Type: ApplicationFiled: September 29, 2016Publication date: September 20, 2018Applicant: SYNGENTA PATRICIPATIONS AGInventors: Daniel Stierli, Thomas Hoffman, Renaud Beaudegnies, Martin Pouliot
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Patent number: 9944944Abstract: This invention includes a novel aad-12 transformation event for herbicide tolerance in soybean plants—referred to herein as pDAB4468-0416. This invention includes a heterologous polynucleotide inserted into a specific site within the genome of a soybean cell. In some embodiments, said event/polynucleotide can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. Additionally, the subject invention provides assays for detecting the presence of the subject event in a sample (a soybean, for example). The assays can be based on the DNA sequence of the recombinant construct, inserted into the soybean genome, and on the genomic sequences flanking the insertion site. Kits and conditions useful in conducting the assays are also provided.Type: GrantFiled: November 24, 2010Date of Patent: April 17, 2018Assignee: Dow AgroSciences LLCInventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Gregory J. Gilles, Terry R. Wright, Julissa Colon, Ricardo A. Barnes, Nathan J. VanOpdorp, Yonghe Bai
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Publication number: 20180077854Abstract: A discharge device includes a plurality of material conveying components, an adjustable shear ledge, and an adjustable shroud to convey materials from a container of a material spreader out onto an open area. The adjustable shear ledge includes at least one longitudinal mounting member such that the adjustable shear ledge may be translated towards or away from the plurality of material conveying components to maintain a predetermined gap distance. The adjustable shroud may also be pivotably connected to the adjustable shear ledge such that the adjustable shroud can be pivoted towards or away from the plurality of material conveying components. The adjustable shear ledge and the adjustable shroud may be moved accordingly to maintain a preferred gap distance and to maintain concentricity with a swing of the material conveying components in order to reduce wear on components and promote spread performance of the material spreader.Type: ApplicationFiled: November 10, 2017Publication date: March 22, 2018Applicant: KUHN NORTH AMERICA, INC.Inventors: Thomas Hoffman, Todd Gibson, Patrick Henry, Claude McFarlane