Patents by Inventor Thomas Hoger

Thomas Hoger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted indoles which are PARP inhibitors
    Patent number: 7087637
    Abstract: The present invention relates to novel indole derivatives, to their preparation and to their use, as inhibitors of the enzyme poly(ADP-ribose)polymerase or PARP (EC 2.4.2.30), for producing drugs.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: August 8, 2006
    Assignee: BASF AG
    Inventors: Roland Grandel, Wilfried Lubisch, Michael Kock, Thomas Hoger, Reinhold Muller, Sabine Schult, Uta Holzenkamp
  • Substituted indoles which are parp inhibitors
    Publication number: 20040067949
    Abstract: The present invention relates to novel indole derivatives, to their preparation and to their use, as inhibitors of the enzyme poly(ADP-ribose)polymerase or PARP (EC 2.4.2.30), for producing drugs.
    Type: Application
    Filed: October 6, 2003
    Publication date: April 8, 2004
    Inventors: Roland Grandel, Wilfried Lubisch, Michael Kock, Thomas Hoger, Reinhold Muller, Sabine Schult, Uta Holzenkamp
  • 2-{3-[4-(2-T-butyl-6-trifluoromethyl-4-pyrimidinyl)-1- piperazinyl] propylthio}-4-pyrimidinol fumarate
    Publication number: 20020143179
    Abstract: The fumaric acid salt of 2-{3-[4-(2-t-butyl-6-trifluoromethyl-4-pyrimidinyl)-1-piperazinyl]propylthio}-4-pyrimidinol is useful for treating disorders which respond to dopamine D3 ligands. It has higher stability at low pH and is therefore particularly suitable for oral administration in pharmaceutical compositions comprising this salt.
    Type: Application
    Filed: January 8, 2002
    Publication date: October 3, 2002
    Inventors: Thomas Hoger, Dorothea Starck, Hans-Jorg Treiber, Bernd Schaefer, Stefan Koser, Marco Thyes, Stefan Blank
  • 2{3-[4-(2-T-BUTYL-6-TRIFLUOROMETHYLPYRIDIN-4-YL) PIPERAZIN-1-YL] PROPYLMERCAPTO} PYRIMIDIN-4-OL-FUMARATE
    Publication number: 20010020022
    Abstract: The fumaric acid salt of 2-{3-[4-(2-t-butyl-6-trifluoromethyl-4-pyrimidinyl)-1-piperazinyl]propylthio}-4-pyrimidinol is useful for treating disorders which respond to dopamine D3 ligands. It has higher stability at low pH and is therefore particularly suitable for oral administration in pharmaceutical compositions comprising this salt.
    Type: Application
    Filed: February 10, 2000
    Publication date: September 6, 2001
    Inventors: STEFAN BLANK, DOROTHEA STARCK, HANS-JORG TREIBER, STEFAN KOSER, BERND SCHAFER, MARCO THYES, THOMAS HOGER
  • N-substituted 3-azabicyclo (3.2.0)heptane derivatives useful as neuroleptics
    Patent number: 6028073
    Abstract: N-substitued 3-azabicyclo[3.2.0]heptane derivatives of formula (I) ##STR1## in which R.sup.1, R.sup.2, A, X, Y and Z have the meanings given in the description, their method of preparation and their use as pharmacological agents.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: February 22, 2000
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerd Steiner, Rainer Munschauer, Thomas Hoger, Liliane Unger, Hans-Jurgen Teschendorf
  • N-substituted azabicycloalkane derivatives, their preparation and use
    Patent number: 5908844
    Abstract: Compounds of the formula I ##STR1## where B, R.sup.1, R.sup.2, n, R.sup.3, A, X, Y and Z have the meanings stated in the description, and their preparation are described. The novel ompounds are suitable for controlling diseases.
    Type: Grant
    Filed: May 6, 1996
    Date of Patent: June 1, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerd Steiner, Rainer Munschauer, Liliane Unger, Hans-Jurgen Teschendorf, Thomas Hoger
  • Subunits of glutamate receptors, their preparation and their use
    Patent number: 5756697
    Abstract: The invention relates to novel subunits for glutamate receptors and to the DNA sequences coding therefor, and to processes for preparing DNA sequences and receptors. The invention furthermore relates to methods for identifying functional ligands for these receptors.
    Type: Grant
    Filed: August 5, 1996
    Date of Patent: May 26, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Thomas Hoger, Andreas Ultsch, Alfred Bach, Sylvia Sterrer, Hans-Georg Lemaire
  • N-substituted azobicycloheptane derivatives, the preparation and use thereof
    Patent number: 5753690
    Abstract: A compound of the formula ##STR1## in which A, R.sup.1 and n have the meanings stated in the description are described. The novel compounds are suitable for controlling diseases.
    Type: Grant
    Filed: February 3, 1997
    Date of Patent: May 19, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerd Steiner, Rainer Munschauer, Thomas Hoger, Liliane Unger, Hans-Jurgen Teschendorf
  • N-substituted azabicycloalkane derivatives, their preparation and use
    Patent number: 5703091
    Abstract: Compounds of the formula I ##STR1## where B, R.sup.1, R.sup.2, n and A have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases.
    Type: Grant
    Filed: June 6, 1996
    Date of Patent: December 30, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerd Steiner, Rainer Munschauer, Liliane Unger, Hans-Jurgen Teschendorf, Thomas Hoger
  • N-substituted azabicycloheptane derivatives, their preparation and use
    Patent number: 5616705
    Abstract: Compounds of the formula I ##STR1## where the substituents have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases.
    Type: Grant
    Filed: April 19, 1996
    Date of Patent: April 1, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerd Steiner, Rainer Munschauer, Liliane Unger, Hans-Jurgen Teschendorf, Thomas Hoger