Patents by Inventor Thomas Horstmann

Thomas Horstmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8350059
    Abstract: Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R1-R12 are as defined herein.
    Type: Grant
    Filed: December 8, 2008
    Date of Patent: January 8, 2013
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Roch Boivin, Silvio A. Campagna, Hong Du, Francis G. Fang, Thomas Horstmann, Charles-Andre Lemelin, Jing Li, Pamela McGuinness, Xiang Niu, Matthew J. Schnaderbeck, Kevin (kuo-ming) Wu, Xiaojie (jeff) Zhu
  • Publication number: 20110237805
    Abstract: Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R1-R12 are as defined herein.
    Type: Application
    Filed: December 8, 2008
    Publication date: September 29, 2011
    Applicant: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Roch Boivin, Silvio A. Campagna, Hong Du, Francis G. Fang, Thomas Horstmann, Charles-Andre Lemelin, Jing Li, Pamela Mcguinness, Xiang Niu, Matthew J. Schnaderbeck, Kevin (kuo-ming) Wu, Xiaojie (Jeff) Zhu
  • Publication number: 20060045846
    Abstract: In one aspect, the present invention provides a method for labeling a terminal olefin, the method comprising a step of treating a terminal olefin substrate having the structure: with a labeled ethylene reagent in the presence of a suitable catalyst under suitable olefin metathesis reaction conditions to form a labeled terminal olefin having the structure: wherein RA and RB are independently hydrogen, or an aliphatic, alicyclic, heteroaliphatic, heterocyclic, aryl or heteroaryl moiety, with the proviso that RA and RB are not each hydrogen, or RA and RB taken together with the carbon atom to which they are attached form an alicyclic or heterocyclic moiety; and * denotes the presence of an isotopic label on the terminal carbon atom.
    Type: Application
    Filed: August 30, 2004
    Publication date: March 2, 2006
    Inventors: Thomas Horstmann, Bryan Lewis