Abstract: A foot brake valve (2?) of a pneumatic brake system in a motor vehicle has an installation plate (4?), on which a brake pedal (14) is pivotably mounted and to which a housing (18?) of a control unit (16, 26) is fastened. A spring-loaded plunger piston (36) in actuating contact with the brake pedal (14) is guided axially movably in an annular collar (50) projecting upward out of the installation plate (4?). For fastening the housing (18?) of the control unit (16, 26) to the installation plate (4?), the housing (18?) has an intermediate flange (48) which is screw-connected to the main part of the housing (18?) and has the annular collar (50). The intermediate flange (48) is coaxially rotatably about a vertical central axis (32), and is connectable in non-positively locking fashion to the installation plate (4?) via a releasable clamping connection (62).

Abstract: Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R1-R12 are as defined herein.

Abstract: Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R1-R12 are as defined herein.

Abstract: In one aspect, the present invention provides a method for labeling a terminal olefin, the method comprising a step of treating a terminal olefin substrate having the structure: with a labeled ethylene reagent in the presence of a suitable catalyst under suitable olefin metathesis reaction conditions to form a labeled terminal olefin having the structure: wherein RA and RB are independently hydrogen, or an aliphatic, alicyclic, heteroaliphatic, heterocyclic, aryl or heteroaryl moiety, with the proviso that RA and RB are not each hydrogen, or RA and RB taken together with the carbon atom to which they are attached form an alicyclic or heterocyclic moiety; and * denotes the presence of an isotopic label on the terminal carbon atom.