Patents by Inventor Thomas Hudyma

Thomas Hudyma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors
    Publication number: 20070184024
    Abstract: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: March 12, 2007
    Publication date: August 9, 2007
    Inventors: Nicholas Meanwell, Robert Gentles, Min Ding, John Bender, John Kadow, Piyasena Hewawasam, Thomas Hudyma, Xiaofan Zheng
  • Indolobenzazepine HCV NS5B inhibitors
    Publication number: 20070078122
    Abstract: The invention encompasses compounds and salts of Formulas I, II, III, and IV as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: September 6, 2006
    Publication date: April 5, 2007
    Inventors: Carl Bergstrom, John Bender, Robert Gentles, Piyasena Hewawasam, Thomas Hudyma, John Kadow, Scott Martin, Alicia Regueiro-Ren, Kap-Sun Yeung, Yong Tu, Katharine Grant-Young, Xiaofan Zheng
  • Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
    Publication number: 20070060565
    Abstract: The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: August 22, 2006
    Publication date: March 15, 2007
    Inventors: Nicholas Meanwell, Robert Gentles, Min Ding, John Bender, John Kadow, Piyasena Hewawasam, Thomas Hudyma, Xiaofan Zheng
  • Inhibitors of HCV replication
    Publication number: 20060166964
    Abstract: Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds.
    Type: Application
    Filed: February 3, 2006
    Publication date: July 27, 2006
    Inventors: Thomas Hudyma, Xiaofan Zheng, Feng He, Min Ding, Carl Bergstrom, Piyasena Hewawasam, Scott Martin, Robert Gentles
  • Inhibitors of HCV replication
    Publication number: 20060046983
    Abstract: Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds.
    Type: Application
    Filed: July 14, 2005
    Publication date: March 2, 2006
    Inventors: Thomas Hudyma, Xiaofan Zheng, Feng He, Min Ding, Carl Bergstrom, Piyasena Hewawasam, Scott Martin, Robert Gentles
  • Inhibitors of HCV replication
    Publication number: 20050119318
    Abstract: Compounds having the structure of formula (I) are disclosed. The compounds can inhibit hepatitis C virus (HCV) replication, and in particular the function of the HCV NS5B protein.
    Type: Application
    Filed: October 27, 2004
    Publication date: June 2, 2005
    Inventors: Thomas Hudyma, Xiaofan Zheng, Jeffrey Romine