Patents by Inventor Thomas Hurley

Thomas Hurley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11944626
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a thiopyrimidinone structure which function as inhibitors of ALDH protein, and their use as therapeutics for the treatment of cancer and other diseases.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: April 2, 2024
    Assignees: The Regents of the University of Michigan, Indiana University Research and Technology Corporation
    Inventors: Scott D. Larsen, Brandt C. Huddle, Kun Yang, Ronald Buckanovich, Thomas Hurley
  • Publication number: 20190255055
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a thiopyrimidinone structure which function as inhibitors of ALDH protein, and their use as therapeutics for the treatment of cancer and other diseases.
    Type: Application
    Filed: June 20, 2017
    Publication date: August 22, 2019
    Inventors: Scott D. Larsen, Brandt C. Huddle, Kun Yang, Ronald Buckanovich, Thomas Hurley
  • Publication number: 20190211815
    Abstract: A lubrication bypass system is disclosed for controlling flow of a lubricant to a reciprocating machine, such as two-stroke engines and two-stroke compressors, based upon one or more operating parameters. The lubrication bypass system can be positioned in fluid communication with a lubrication system that transports a primary flow of the lubricant from a lubricant reservoir to the reciprocating machine cylinder at a predetermined primary flow rate. The lubrication bypass system can be configured to divert a portion of the primary flow, a bypass flow, from the lubrication system at a bypass flow rate based upon the operating parameters. As a result, a secondary flow of lubricant remaining within the lubrication system can be supplied to the reciprocating machine at a secondary flow rate that is less than the primary flow rate. In this manner, the lubrication bypass system can regulate the secondary flow rate.
    Type: Application
    Filed: January 8, 2018
    Publication date: July 11, 2019
    Inventors: Ashraf O. Elmessidi, Moien Farmahini, Thomas Hurley, Pejman Kazempoor, Nasr Alkadi
  • Publication number: 20080072579
    Abstract: A low emissions 2-stroke natural gas fueled engine includes at least one cylinder with an exhaust port in communication with a silencer/catalytic converter unit. The unit has first and second volumes in communication with each other. The first volume dampens spurious exhaust pressure excursions and removes particulates in the exhaust. The second volume houses an oxidation catalyst for treating exhaust to reduce exhaust emissions. The engine oil has at most 10 ppm zinc content to reduce metal poisons contained in the exhaust prior to contact with the oxidation catalyst. The engine oil preferably has a very low ash content to minimize sulfur combustion components in the exhaust to reduce masking of the oxidation catalyst. The first volume preferably has a pressure relief valve set to relieve at a pressure greater than the maximum normal operating pressure of the engine to avoid excessive pressure excursions of the engine exhaust from damaging the oxidation catalyst.
    Type: Application
    Filed: October 31, 2007
    Publication date: March 27, 2008
    Applicant: CAMERON INTERNATIONAL CORPORATION
    Inventors: Bruce Chrisman, Thomas Hurley
  • Publication number: 20080053078
    Abstract: A low emissions 2-stroke natural gas fueled engine includes at least one cylinder with an exhaust port in communication with a silencer/catalytic converter unit. The unit has first and second volumes in communication with each other. The first volume dampens spurious exhaust pressure excursions and removes particulates in the exhaust. The second volume houses an oxidation catalyst for treating exhaust to reduce exhaust emissions. The engine oil has at most 10 ppm zinc content to reduce metal poisons contained in the exhaust prior to contact with the oxidation catalyst. The engine oil preferably has a very low ash content to minimize sulfur combustion components in the exhaust to reduce masking of the oxidation catalyst. The first volume preferably has a pressure relief valve set to relieve at a pressure greater than the maximum normal operating pressure of the engine to avoid excessive pressure excursions of the engine exhaust from damaging the oxidation catalyst.
    Type: Application
    Filed: October 31, 2007
    Publication date: March 6, 2008
    Applicant: CAMERON INTERNATIONAL CORPORATION
    Inventors: Bruce Chrisman, Thomas Hurley
  • Publication number: 20070245713
    Abstract: A low emissions 2-stroke natural gas fueled engine includes at least one cylinder with an exhaust port in communication with a silencer/catalytic converter unit. The unit has first and second volumes in communication with each other. The first volume dampens spurious exhaust pressure excursions and removes particulates in the exhaust. The second volume houses an oxidation catalyst for treating exhaust to reduce exhaust emissions. The engine oil has at most 10 ppm zinc content to reduce metal poisons contained in the exhaust prior to contact with the oxidation catalyst. The engine oil preferably has a very low ash content to minimize sulfur combustion components in the exhaust to reduce masking of the oxidation catalyst. The first volume preferably has a pressure relief valve set to relieve at a pressure greater than the maximum normal operating pressure of the engine to avoid excessive pressure excursions of the engine exhaust from damaging the oxidation catalyst.
    Type: Application
    Filed: June 27, 2007
    Publication date: October 25, 2007
    Applicant: Cameron International Corporation
    Inventors: Bruce Chrisman, Thomas Hurley
  • Publication number: 20070079702
    Abstract: A hydrocarbon adsorber and a thermoplastic resin combined and formed to a porous scavenger for insertion into the air intake system of a motor vehicle engine. The resulting porous scavenger adsorbs volatile hydrocarbon molecules from raw fuel remaining in the air intake when the engine is shut off. The adsorbed molecules are then stripped or purged from the scavenger and reintroduced into the air intake when the engine is next started.
    Type: Application
    Filed: October 11, 2005
    Publication date: April 12, 2007
    Applicant: Multisorb Technologies, Inc.
    Inventors: Thomas Hurley, Samuel Incorvia
  • Publication number: 20060242186
    Abstract: A system and method for processing thermal signature data is provided. The system provides a thermal signature data processor that analyzes one or more pixels to determine whether an aspect of an alarm-worthy event has occurred. In one embodiment, the system analyzes visual data with relation to the thermal signature data to determine whether an alarm-worthy event (e.g., intrusion) has occurred and subsequently generates an alarm to indicate an intrusion or alarm-worthy event.
    Type: Application
    Filed: April 26, 2005
    Publication date: October 26, 2006
    Inventor: Thomas Hurley
  • Publication number: 20060032851
    Abstract: A combination of a container body, an opening in said container body, an inner wall on said container body, a basket, a plurality of fingers on said basket engaging said inner wall, and a sorbent body in said basket.
    Type: Application
    Filed: October 17, 2005
    Publication date: February 16, 2006
    Applicant: Multisorb Technologies, Inc.
    Inventors: Thomas Hurley, Thomas Powers
  • Publication number: 20050262835
    Abstract: A low emissions 2-stroke natural gas fueled engine includes at least one cylinder with an exhaust port in communication with a silencer/catalytic converter unit. The unit has first and second volumes in communication with each other. The first volume dampens spurious exhaust pressure excursions and removes particulates in the exhaust. The second volume houses an oxidation catalyst for treating exhaust to reduce exhaust emissions. The engine oil has at most 10 ppm zinc content to reduce metal poisons contained in the exhaust prior to contact with the oxidation catalyst. The engine oil preferably has a very low ash content to minimize sulfur combustion components in the exhaust to reduce masking of the oxidation catalyst. The first volume preferably has a pressure relief valve set to relieve at a pressure greater than the maximum normal operating pressure of the engine to avoid excessive pressure excursions of the engine exhaust from damaging the oxidation catalyst.
    Type: Application
    Filed: May 25, 2004
    Publication date: December 1, 2005
    Inventors: Bruce Chrisman, Thomas Hurley
  • Publication number: 20050184025
    Abstract: A combination of a container and a sorbent wherein a support is provided in the neck of a container to support a sorbent out of contact with the contents of the container.
    Type: Application
    Filed: February 25, 2004
    Publication date: August 25, 2005
    Inventors: Thomas Hurley, Thomas Powers
  • Publication number: 20050056151
    Abstract: An adsorbent capsule including a core of pressed adsorbent material having a water-insoluble binder, and a water-vapor or permeable coating of water-based resin, namely, hydroxypropylmethylcellulose.
    Type: Application
    Filed: September 11, 2003
    Publication date: March 17, 2005
    Inventors: Thomas Hurley, Keith Ware