Abstract: The present invention is a medication reminder system and method for use with blister packs containing medications to be taken by a patient wherein the system alerts the patient when to take the medication contained in a particular blister. An audible alarm and a light indicate which blister is to be opened to remove the medication. The system comprises a case large enough to enclose a blister pack and has top and bottom halves that are releasably connected together. A circuit board comprising the electronics that operate the system is placed on top of the blister pack and is enclosed in the case along with the blister pack. Both the circuit board and the top case half have openings that allow the blisters of the pack to pass through. Openings on the bottom case half permit the medications in the blisters to be removed. The circuit board is programmable to set the time of an internal clock and to set up to four alarms a day when medications are to be taken.