Abstract: A heart valve assembly comprises a first prosthesis configured to expand from an unexpanded state to an expanded state at which the first annular prosthesis contacts native tissue of a body lumen. The heart valve assembly also comprises a second prosthesis comprising a valve, and a connection adapter that secures the second prosthesis to the first prosthesis, the connection adapter having a multi-lobed circumference.

Abstract: Non-expandable space-occupying devices for treating voids within the body are disclosed. The devices can have multiple non-expandable space-occupying elements connected to a flexible leaden Methods of making and using the devices are also disclosed.

Abstract: The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.

Abstract: The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.

Abstract: A method of using a prosthetic heart valve assembly can include implanting a first prosthesis directly into a native annulus. The first prosthesis can have a central longitudinal axis and a first engagement element. The method can also include engaging the first engagement element of the first prosthesis with a second engagement element of a second prosthesis to securely couple the second prosthesis to the first prosthesis. The second prosthesis can have a prosthetic valve. The first engagement element engages the second engagement element by moving the second prosthesis towards the first prosthesis in a direction generally parallel to the central longitudinal axis until the first engagement element engages the second engagement element.

Abstract: In one embodiment of the present invention there is provided a filter having a first elongate member having a first section and a second section; a second elongate member having a first section and a second section; a first rounded frame formed by the first sections; a second rounded frame formed by the second sections; and a material removal structure supported by the first rounded frame. In another embodiment of the present invention there is provided a filter, having a first elongate member having a first spiral section and a second spiral section; a second elongate member having a first spiral section and a second spiral section; and a material capture structure extending between the first spiral sections.

Abstract: In one embodiment of the present invention there is provided a filter having a first support member having a first end and a second end; a second support member joined to the first support member at the first end and positioned adjacent the first support member to form a support frame; a material capture structure within the support frame; and a retrieval feature on the first end and on the second end. In one aspect, the first support member or the second support member has a spiral shape.

Abstract: In one embodiment of the present invention there is provided an implantable filter. The implantable filter can include a first support member having a first end and a second end; a second support member positioned adjacent the first support member to form a loop between the first end and the second end of the first support member; and a filtering structure attached to the loop by a plurality of segmented tubes.

Abstract: In one embodiment of the present invention there is provided a method of filtering blood flow in a lumen by positioning an open loop filter support structure within a lumen; maintaining a position of the open loop filter support structure within the lumen using radial force generated by the open loop filter support structure; and filtering blood flow in the lumen using a filter supported by the open loop filter support structure. In one aspect, there is also applying radial force generated by the open loop filter support structure along the axial dimension of the lumen.

Abstract: In one embodiment of the present invention there is provided a method of positioning within a lumen a filtering device having a filter and a filter support structure by advancing the filtering device along the lumen while the filter and the filter support structure are in a stowed configuration; releasing the filter and the filter support structure from the stowed configuration so that opposing spiral elements of the filter support structure are in atraumatic contact with the lumen and the filter is positioned across the lumen flow path.

Abstract: In one embodiment of the present invention there is provided a biodegradable implantable device. The biodegradable implant device can include one or more elongate spiral support structures that can be biodegradable. Some embodiments can further include a material capture structure that can be biodegradable. A pharmacological agent can also be incorporated into the elongate spiral support structures and/or the material capture structure.

Abstract: In one embodiment of the present invention there is provided a method of filtering blood flow in a lumen by positioning an open loop filter support structure within a lumen; maintaining a position of the open loop filter support structure within the lumen using radial force generated by the open loop filter support structure; and filtering blood flow in the lumen using a filter supported by the open loop filter support structure. In one aspect, there is also applying radial force generated by the open loop filter support structure along the axial dimension of the lumen.

Abstract: In one embodiment of the present invention there is provided an implantable filter. The filter can include a first support member having a first end and a second end; a second support member positioned adjacent the first support member to form an open loop between the first end and the second end of the first support member; a wrapping material wrapped around a portion of the first support member and a portion of the second support member that forms the open loop; and a filtering structure attached to the open loop by the wrapping material.

Abstract: Non-expandable space-occupying devices for treating voids within the body are disclosed. The devices can have multiple non-expandable space-occupying elements connected to a flexible leader. Methods of making and using the devices are also disclosed.

Abstract: There is described an endoluminal filter having an end cap having a lumen sized to receive there through a guidewire used in the positioning of the filter within the vasculature. There is a first support member with a pre-formed counter clockwise spiral shape and a second support member with a pre-formed clockwise spiral shape positioned adjacent to one another to form a proximal support frame, a distal support frame with a crossover between the proximal support frame and the distal support frame with a proximal portion of the first and the second spiral support members being attached to the end cap. A material capture structure having a rim and an apex with the rim attached to the proximal support frame and the apex extending distally through without attaching to the distal support frame.

Abstract: Biologically implantable prostheses and methods of using the same are disclosed. In one embodiment, a heart valve assembly includes a first annular prosthesis sized for introduction into a tissue annulus in a heart; a first magnet in the first prosthesis; a second valve prosthesis separate and disconnected from the first prosthesis and comprising a heart valve crown with leaflets, the second prosthesis configured for introduction into the tissue annulus after introducing the first prosthesis into the tissue annulus; and a second magnet in the second prosthesis, wherein an attraction between the first magnet and the second magnet engages the first prosthesis to the second prosthesis to attach the second prosthesis to the first prosthesis in the tissue annulus.

Abstract: There are described a number of different coated endoluminal filters. The filters include a support structure formed from two shape memory metal wires joined at a first end and a second end. There is a first loop formed by the two wires and positioned directly adjacent to the first end. There is a second loop formed by the two wires and positioned directly adjacent to the second end. A filtering structure is formed from a suture material and positioned across the two metal wires so as to be within one of the two loops. There is a coating over at least a portion of the wires forming one of the two loops of the support structure containing the filtering structure. In one aspect, the coating is used to secure the filtering structure to the at least one of the two loops of the support structure.

Abstract: In one embodiment of the present invention there is provided a method of providing protection during a procedure performed in the vasculature using an open loop filter device comprising two elongate support members positioned to form at least one crossover location between adjacent open loops of the device. The method may also include placing the open loop device down stream of a location in the vasculature performing a procedure to treat the vasculature in proximity to the location; and capturing debris released during the procedure in a material capture structure suspended between the elongate support members and across the vessel. Additionally, there can be a step of maintaining the open loop filter device downstream of the location along the wall of the vasculature while permitting movement along the wall of the vasculature of the two elongate support members adjacent the material capture structure.