Patents by Inventor Thomas J. Kryzer

Thomas J. Kryzer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND MATERIALS FOR IDENTIFYING AND TREATING AUTOIMMUNE GFAP ASTROCYTOPATHY
    Publication number: 20220357322
    Abstract: This document provides methods and materials involved in identifying and treating autoimmune GFAP (glial fibrillary acidic protein) astrocytopathy, a novel meningoencephalomyelitis, in humans as well as methods and materials for identifying and offering early treatment for patients having autoimmune GFAP astrocytopathy whose autoantibody profile predicts a high likelihood of having underlying cancer (e.g., adenocarcinoma or teratoma).
    Type: Application
    Filed: July 21, 2022
    Publication date: November 10, 2022
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Andrew McKeon, Boyan Fang, Shannon Hinson, Thomas J. Kryzer
  • Methods and materials for identifying and treating autoimmune GFAP astrocytopathy
    Patent number: 11402379
    Abstract: This document provides methods and materials involved in identifying and treating autoimmune GFAP (glial fibrillary acidic protein) astrocytopathy, a novel meningoencephalomyelitis, in humans as well as methods and materials for identifying and offering early treatment for patients having autoimmune GFAP astrocytopathy whose autoantibody profile predicts a high likelihood of having underlying cancer (e.g., adenocarcinoma or teratoma).
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: August 2, 2022
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Andrew McKeon, Boyan Fang, Shannon Hinson, Thomas J. Kryzer
  • AUTOANTIBODIES AS BIOMARKER OF PARANEOPLASTIC ENCEPHALITIS ASSOCIATED WITH TESTICULAR CANCER
    Publication number: 20220196662
    Abstract: This disclosure describes methods and compositions for detecting the presence of a Kelch-like protein 11 autoantibody in a biological sample. Also provided are methods of treating subjects with testicular cancer or a premalignant condition and paraneoplastic encephalomyelitis.
    Type: Application
    Filed: March 13, 2020
    Publication date: June 23, 2022
    Inventors: Joseph L. DeRisi, Michael R. Wilson, Caleigh Mandel-Brehm, Brian O'Donovan, Sean J. Pittock, Divyanshu Dubey, Thomas J. Kryzer, Vanda A. Lennon, Andrew McKeon
  • ASSESSING AND TREATING GERM CELL TUMORS AND PARANEOPLASTIC AUTOIMMUNITY
    Publication number: 20220120744
    Abstract: Materials and methods for detecting LUZP4 IgG in a mammal, as well as materials and methods for using LUZP4 as a serological biomarker of germ cell tumors and paraneoplastic autoimmunity, are provided herein. Also provided herein are materials and methods for treating a mammal identified as having anti-LUZP4 autoantibodies.
    Type: Application
    Filed: July 24, 2020
    Publication date: April 21, 2022
    Inventors: Vanda A. Lennon, Andrew McKeon, Thomas J. Kryzer, Sean J. Pittock, Divyanshu Dubey
  • Materials and methods for evaluating and treating cancer
    Patent number: 11061027
    Abstract: This document provides methods and materials for detecting PCA-2-specific autoantibodies, which can be associated with paraneoplastic neurological disorders and cancers associated with PCA-2-specific autoantibodies.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: July 13, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Sean J. Pittock, Thomas J. Kryzer, Avi Gadoth, Andrew McKeon, Vanda A. Lennon, James P. Fryer
  • MATERIALS AND METHODS FOR EVALUATING AND TREATING CANCER
    Publication number: 20200041505
    Abstract: This document provides methods and materials for detecting PCA-2-specific autoantibodies, which can be associated with paraneoplastic neurological disorders and cancers associated with PCA-2-specific autoantibodies.
    Type: Application
    Filed: September 12, 2017
    Publication date: February 6, 2020
    Inventors: Sean J. Pittock, Thomas J. Kryzer, Avi Gadoth, Andrew McKeon, Vanda A. Lennon, James P. Fryer
  • METHODS AND MATERIALS FOR IDENTIFYING AND TREATING AUTOIMMUNE GFAP ASTROCYTOPATHY
    Publication number: 20190376965
    Abstract: This document provides methods and materials involved in identifying and treating autoimmune GFAP (glial fibrillary acidic protein) astrocytopathy, a novel meningoencephalomyelitis, in humans as well as methods and materials for identifying and offering early treatment for patients having autoimmune GFAP astrocytopathy whose autoantibody profile predicts a high likelihood of having underlying cancer (e.g., adenocarcinoma or teratoma).
    Type: Application
    Filed: September 6, 2017
    Publication date: December 12, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Andrew McKeon, Boyan Fang, Shannon Hinson, Thomas J. Kryzer
  • PERIPHERIN-SPECIFIC AUTOANTIBODIES AS A MARKER FOR NEUROLOGICAL AND ENDOCRINOLOGICAL DISEASE
    Publication number: 20140377883
    Abstract: The present invention provides for methods and materials for detecting a peripherin-specific autoantibody, which can be associated with neurological and endocrinological disease.
    Type: Application
    Filed: September 8, 2014
    Publication date: December 25, 2014
    Inventors: Vanda A. Lennon, Jayne Chamberlain-Banoub, Thomas J. Kryzer, Sean J. Pittock, Anna Maria Oprescu
  • METHODS AND COMPOSITIONS FOR DETECTING THE PRESENCE OF ONE OR MORE AUTOANTIBODIES
    Publication number: 20140315225
    Abstract: This disclosure describes methods and compositions for immunohistochemically detecting the presence of a SRP autoantibody in a biological sample.
    Type: Application
    Filed: September 14, 2012
    Publication date: October 23, 2014
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Vanda A. Lennon, Thomas J. Kryzer, James P. Fryer, Sean J. Pittock, Metha Apiwattanakul
  • MARKER FOR NEUROMYELITIS OPTICA
    Publication number: 20140314796
    Abstract: The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO).
    Type: Application
    Filed: June 2, 2014
    Publication date: October 23, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Thomas J. Kryzer
  • Methods of treating neuromyelitis optica (NMO)
    Patent number: 8524508
    Abstract: The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO).
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: September 3, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Thomas J Kryzer
  • PERIPHERIN-SPECIFIC AUTOANTIBODIES AS A MARKER FOR NEUROLOGICAL AND ENDOCRINOLOGICAL DISEASE
    Publication number: 20130023484
    Abstract: The present invention provides for methods and materials for detecting a peripherin-specific autoantibody, which can be associated with neurological and endocrinological disease.
    Type: Application
    Filed: January 4, 2011
    Publication date: January 24, 2013
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Vanda A. Lennon, Jayne Chamberlain, Thomas J. Kryzer, Sean J. Pittock, Anna Maria Oprescu
  • MARKER FOR NEUROMYELITIS OPTICA
    Publication number: 20120219969
    Abstract: The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO).
    Type: Application
    Filed: May 14, 2012
    Publication date: August 30, 2012
    Inventors: Vanda A. Lennon, Thomas J. Kryzer
  • Method of detecting a neuromyelitis optica specific-autoantibody by an antigenic aquaporin-4 polypeptide
    Patent number: 7947254
    Abstract: The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO).
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: May 24, 2011
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Thomas J. Kryzer
  • MARKER FOR NEUROMYELITIS OPTICA
    Publication number: 20090143710
    Abstract: The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO).
    Type: Application
    Filed: April 18, 2008
    Publication date: June 4, 2009
    Inventors: Vanda A. Lennon, Thomas J. Kryzer
  • Marker for Neuromyelitis Optica
    Publication number: 20080145870
    Abstract: The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO).
    Type: Application
    Filed: July 14, 2006
    Publication date: June 19, 2008
    Inventors: Vanda A. Lennon, Thomas J. Kryzer
  • Marker for neuromyelitis optica
    Patent number: 7101679
    Abstract: The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO).
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: September 5, 2006
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Vanda A. Lennon, Thomas J. Kryzer