Patents by Inventor Thomas J. Lynch

Thomas J. Lynch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11896611
    Abstract: A phytochemical and nutraceutical composition and method for protection against a wide spectrum of viral and bacterial infections, including Covid-19, and for treatment of established infection and infectious inflammation. The composition includes a novel combination of vitamin, mineral, nutraceutical and phytochemical supplements. The composition of supplements and method may be compounded as a pill, tablet, powder, capsule or liquid be taken orally one or more times per day. Vitamin C and vitamin E along with zinc complexed with pyrithione or citrate are used in conjunction with nutraceuticals and phytochemicals provided, respectively, as immune boosters and antiviral agents along with anti-inflammatory nutraceuticals and phytochemicals.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: February 13, 2024
    Inventors: David A. Cuddeback, Thomas J. Lynch
  • Patent number: 11753580
    Abstract: An inverse emulsion composition comprising: one or more hydrophobic liquids having a boiling point at least about 100° C.; up to about 38% by weight of one or more acrylamide-(co)polymers; one or more emulsifier surfactants; and one or more inverting surfactants; wherein, when the composition is inverted in an aqueous solution, it provides an inverted solution having a filter ratio using a 1.2 micron filter (FR1.2) of about 1.5 or less.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: September 12, 2023
    Assignee: KEMIRA OYJ
    Inventors: Logan Jackson, Thomas J. Lynch, Ronald Robinson, Frances Fournier, Hong Yang, Sukhjit Aujla, Do Hoon Kim, Dennis Arun Alexis
  • Patent number: 11299409
    Abstract: Provided herein are liquid polymer (LP) compositions comprising an acrylamide (co)polymer, as well as methods for preparing inverted polymer solutions by inverting these LP compositions in an aqueous fluid. The resulting inverted polymer solutions can have a concentration of acrylamide (co)polymer of from about 50 to about 15,000 ppm, and a filter ratio of 1.5 or less at 15 psi using a 1.2 ?m filter. Also provided are methods of using these inverted polymer solutions in dewatering, clarification, flocculation and/or thickening applications, and the like.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: April 12, 2022
    Assignees: KEMIRA OYJ, CHEVRON U.S.A. INC.
    Inventors: Logan Jackson, Thomas J. Lynch, Ronald Robinson, Frances Fournier, Hong Yang, Sukhjit Aujla, Do Hoon Kim, Dennis Arun Alexis, Varadarajan Dwarakanath, David Espinosa, Taimur Malik
  • Publication number: 20210315930
    Abstract: A nutraceutical composition for protection against a wide spectrum of viral and bacterial infections and for treatment of established infection and infectious inflammation. The nutraceutical composition includes a novel combination of vitamin, mineral and herbal or other natural and organic supplements. The composition of supplements may be compounded as a pill, tablet, powder, capsule or liquid be taken orally one or more times per day. Vitamin C and vitamin E along with zinc complexed with pyrithione or citrate are used in conjunction with nutraceuticals provided as immune boosters and antiviral agents along with possible anti-inflammatory herbs or other anti-inflammatory substances.
    Type: Application
    Filed: April 14, 2020
    Publication date: October 14, 2021
    Inventors: David A. Cuddeback, Thomas J. Lynch
  • Publication number: 20210255170
    Abstract: Compositions and methods to modulate Lef-1/TCF/Wnt signaling ex vivo or in vivo, and assays to detect those modulators, are described.
    Type: Application
    Filed: March 13, 2019
    Publication date: August 19, 2021
    Inventors: John F. Engelhardt, Thomas J. Lynch, Preston J. Anderson, Weam Shahin
  • Publication number: 20210017604
    Abstract: Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
    Type: Application
    Filed: April 21, 2020
    Publication date: January 21, 2021
    Applicants: The General Hospital Corporation, Dana-Farber Cancer Institute, Inc.
    Inventors: Daphne Winifred BELL, Daniel A. HABER, Pasi Antero JANNE, Bruce E. JOHNSON, Thomas J. LYNCH, Matthew MEYERSON, Juan Guillermo PAEZ, William R. SELLERS, Jeffrey E. SETTLEMAN, Raffaella SORDELLA
  • Patent number: 10669589
    Abstract: Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: June 2, 2020
    Assignees: The General Hospital Corporation, Dana-Farber Cancer Institute, Inc.
    Inventors: Daphne Winifred Bell, Daniel A. Haber, Pasi Antero Janne, Bruce E. Johnson, Thomas J. Lynch, Matthew Meyerson, Juan Guillermo Paez, William R. Sellers, Jeffrey E. Settleman, Raffaella Sordella
  • Publication number: 20200165778
    Abstract: Provided herein are liquid polymer (LP) compositions comprising an acrylamide (co)polymer, as well as methods for preparing inverted polymer solutions by inverting these LP compositions in an aqueous fluid. The resulting inverted polymer solutions can have a concentration of acrylamide (co)polymer of from about 50 to about 15,000 ppm, and a filter ratio of 1.5 or less at 15 psi using a 1.2 ?m filter. Also provided are methods of using these inverted polymer solutions in dewatering, clarification, flocculation and/or thickening applications, and the like.
    Type: Application
    Filed: December 7, 2016
    Publication date: May 28, 2020
    Inventors: Logan Jackson, Thomas J. Lynch, Ronald Robinson, Frances Fournier, Hong Yang, Sukhjit Aujla, Do Hoon Kim, Dennis Arun Alexis, Varadarajan Dwarakanath, David Espinosa, Taimur Malik
  • Patent number: 10378154
    Abstract: The present disclosure relates to a method and composition for increasing wet and/or dry strength of a paper product. The method comprises adding a composition comprising at least one polymer having a molecular weight more than 0.5 million Dalton and a degradation agent to a pulp suspension, and forming said paper product.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: August 13, 2019
    Assignee: Kemira Oyj
    Inventors: Yuping Luo, Jiang Li, Thomas J. Lynch, Jenna Sue Rabideau, Scott Rosencrance
  • Publication number: 20190241793
    Abstract: An inverse emulsion composition comprising: one or more hydrophobic liquids having a boiling point at least about 100° C.; up to about 38% by weight of one or more acrylamide-(co)polymers; one or more emulsifier surfactants; and one or more inverting surfactants; wherein, when the composition is inverted in an aqueous solution, it provides an inverted solution having a filter ratio using a 1.2 micron filter (FR1.2) of about 1.5 or less.
    Type: Application
    Filed: April 17, 2019
    Publication date: August 8, 2019
    Inventors: Logan Jackson, Thomas J. Lynch, Ronald Robinson, Frances Fournier, Hong Yang, Sukhjit Aujla, Do Hoon Kim, Dennis Arun Alexis
  • Publication number: 20190241794
    Abstract: Liquid polymer compositions comprising: one or more hydrophobic liquids having a boiling point at least about 100° C.; at least about 39% by weight of one or more acrylamide-(co)polymers; one or more emulsifier surfactants; and one or more inverting surfactants; wherein, when the composition is inverted in an aqueous solution, it provides an inverted solution having a filter ratio using a 1.2 micron filter (FR1.2) of about 1.5 or less.
    Type: Application
    Filed: April 17, 2019
    Publication date: August 8, 2019
    Inventors: Logan Jackson, Thomas J. Lynch, Ronald Robinson, Frances Fournier, Hong Yang, Sukhjit Aujla, Do Hoon Kim, Dennis Arun Alexis
  • Publication number: 20190203104
    Abstract: Liquid polymer compositions comprising: one or more hydrophobic liquids having a boiling point at least about 100° C.; at least about 39% by weight of one or more acrylamide-(co)polymers; one or more emulsifier surfactants; and one or more inverting surfactants; wherein, when the composition is inverted in an aqueous solution, it provides an inverted solution having a filter ratio using a 1.2 micron filter (FR1.2) of about 1.5 or less.
    Type: Application
    Filed: December 7, 2016
    Publication date: July 4, 2019
    Inventors: Logan Jackson, Thomas J. Lynch, Ronald Robinson, Frances Fournier, Hong Yang, Sukhjit Aujla, Do Hoon Kim, Dennis Arun Alexis
  • Publication number: 20180362833
    Abstract: An inverse emulsion composition comprising: one or more hydrophobic liquids having a boiling point at least about 100° C.; up to about 38% by weight of one or more acrylamide-(co)polymers; one or more emulsifier surfactants; and one or more inverting surfactants; wherein, when the composition is inverted in an aqueous solution, it provides an inverted solution having a filter ratio using a 1.2 micron filter (FR 1.2) of about 1.5 or less.
    Type: Application
    Filed: December 7, 2016
    Publication date: December 20, 2018
    Inventors: Logan Jackson, Thomas J. Lynch, Ronald Robinson, Frances Fournier, Hong Yang, Sukhjit Aujla, Do Hoon Kim, Dennis Arun Alexis
  • Publication number: 20180251860
    Abstract: Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
    Type: Application
    Filed: May 16, 2018
    Publication date: September 6, 2018
    Applicants: The General Hospital Corporation, Dana-Farber Cancer Institute, Inc.
    Inventors: Daphne Winifred BELL, Daniel A. HABER, Pasi Antero JANNE, Bruce E. JOHNSON, Thomas J. LYNCH, Matthew MEYERSON, Juan Guillermo PAEZ, William R. SELLERS, Jeffrey E. SETTLEMAN, Raffaella SORDELLA
  • Patent number: 10000815
    Abstract: Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: June 19, 2018
    Assignees: THE GENERAL HOSPITAL CORPORATION, DANA-FARBER CANCER INSTITUTE, INC
    Inventors: Daphne Winifred Bell, Daniel A. Haber, Pasi Antero Janne, Bruce E. Johnson, Thomas J. Lynch, Matthew Meyerson, Juan Guillermo Paez, William R. Sellers, Jeffrey E. Settleman, Raffaella Sordella
  • Publication number: 20180105988
    Abstract: The present disclosure relates to a method and composition for increasing wet and/or dry strength of a paper product. The method comprises adding a composition comprising at least one polymer having a molecular weight more than 0.5 million Dalton and a degradation agent to a pulp suspension, and forming said paper product.
    Type: Application
    Filed: April 19, 2016
    Publication date: April 19, 2018
    Applicant: Kemira Oyj
    Inventors: Yuping LUO, Jiang LI, Thomas J. LYNCH, Jenna Sue RABIDEAU, Scott ROSENCRANCE
  • Publication number: 20150176081
    Abstract: Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
    Type: Application
    Filed: March 4, 2015
    Publication date: June 25, 2015
    Inventors: Daphne Winifred BELL, Daniel A. HABER, Pasi Antero JANNE, Bruce E. JOHNSON, Thomas J. LYNCH, Matthew MEYERSON, Juan Guillermo PAEZ, William R. SELLERS, Jeffrey E. SETTLEMAN, Raffaella SORDELLA
  • Patent number: 9035036
    Abstract: Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: May 19, 2015
    Assignees: The General Hospital, Dana-Farber Cancer Institute, Inc.
    Inventors: Daphne Winifred Bell, Daniel A. Haber, Pasi Antero Janne, Bruce E. Johnson, Thomas J. Lynch, Matthew Meyerson, Juan Guillermo Paez, William R. Sellers, Jeffrey E. Settleman, Raffaella Sordella
  • Patent number: 8465916
    Abstract: The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: June 18, 2013
    Assignees: The General Hospital Corporation, Dana Farber Cancer Institute, Inc.
    Inventors: Daphne Winifred Bell, Daniel A. Haber, Pasi Antero Janne, Bruce E. Johnston, Thomas J. Lynch, Matthew Meyerson, Juan Guillermo Paez, William R. Sellers, Jeffrey E. Settleman, Raffaella Sordella
  • Patent number: 8105769
    Abstract: The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: January 31, 2012
    Assignees: The General Hospital Corporation, Dana-Farber Cancer Institute, Inc.
    Inventors: Daphne Winifred Bell, Daniel A. Haber, Pasi Antero Janne, Bruce E. Johnston, Thomas J. Lynch, Matthew Meyerson, Juan Guillermo Paez, William R. Sellers, Jeffrey E. Settleman, Raffaella Sordella