Patents by Inventor Thomas J. O'Connell

Thomas J. O'Connell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240125719
    Abstract: A defined peak region residing between about 3.2 and 3.4 ppm of a proton NMR spectrum of an in vitro biosample is electronically evaluated to determine a level of trimethylamine-N-oxide (“TMAO”). The biosample may be any suitable biosamples including human serum with a normal biologic range of between about 1-50 ?M or urine with a normal biologic range of between about 0-1000 ?M.
    Type: Application
    Filed: September 21, 2023
    Publication date: April 18, 2024
    Applicant: Liposcience, Inc.
    Inventors: James D. Otvos, Elias J. Jeyarajah, Justyna E. Wolak-Dinsmore, Thomas M. O'Connell, Dennis W. Bennett, Steven P. Matyus, Stanley L. Hazen
  • Patent number: 11354583
    Abstract: Logical rules can be automatically generated for use with event detection systems according to some aspects of the present disclosure. For example, a computing device can extract a group of logical rules from trained decision trees and apply a test data set to the group of logical rules to determine count values corresponding to the logical rules. The computing device can then determine performance metric values based on the count values, select a subset of logical rules from among the group of logical rules based on the performance metric values, and provide at least one logical rule in the subset for use with an event detection system. The event detection system can be configured to detect an event in relation to a target data set that was not used to train the decision trees.
    Type: Grant
    Filed: April 8, 2021
    Date of Patent: June 7, 2022
    Assignee: SAS INSTITUTE INC.
    Inventors: Hamoon Azizsoltani, Prathaban Mookiah, Weichen Wang, Thomas J. O'Connell
  • Publication number: 20220121967
    Abstract: Logical rules can be automatically generated for use with event detection systems according to some aspects of the present disclosure. For example, a computing device can extract a group of logical rules from trained decision trees and apply a test data set to the group of logical rules to determine count values corresponding to the logical rules. The computing device can then determine performance metric values based on the count values, select a subset of logical rules from among the group of logical rules based on the performance metric values, and provide at least one logical rule in the subset for use with an event detection system. The event detection system can be configured to detect an event in relation to a target data set that was not used to train the decision trees.
    Type: Application
    Filed: April 8, 2021
    Publication date: April 21, 2022
    Applicant: SAS Institute Inc.
    Inventors: Hamoon Azizsoltani, Prathaban Mookiah, Weichen Wang, Thomas J. O'Connell
  • Patent number: 10726123
    Abstract: Malicious activity can be detected and prevented in real-time or otherwise. For example, a system of the present disclosure can receive a request from a user to obtain access to an entity, determine data objects based on the request, and access data-object network definitions corresponding to the determined data objects. The system can also receive a profile for the user indicating behavioral information relating to the user. The system can then determine a likelihood that the request is associated with malicious activity based on (i) the data objects, (ii) the profile, and (iii) the data-object network definitions. The system can allow or deny the user access to the entity based on the likelihood that the request is associated with malicious activity.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: July 28, 2020
    Assignee: SAS INSTITUTE INC.
    Inventors: Prathaban Mookiah, Ian Holmes, John Robert Watkins, Thomas J. O'Connell
  • Patent number: 4575452
    Abstract: A method and kit for the optical detection of proteins and nucleic acids in a matrix, such as polyacrylamide electrophoresis gels. The method comprises fixing the proteins and nucleic acids in the matrix using aromatic sulfonic acids having tertiary amines capable of forming coordination complexes with silver ion.
    Type: Grant
    Filed: September 21, 1984
    Date of Patent: March 11, 1986
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Duk H. Lee, Thomas J. O'Connell, III