Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: An apparatus and process for molding workpieces usable for consumer products. The workpieces may be injection molded with a cavity formed by a core pin and have an undercut, such as internal threads, in the cavity. The apparatus has a drive system with a stripper plate mounted for alternatingly forward and retracting axial movement. The stripper plate is axially driven and drives a stripper sleeve barrel cam and a core pin base barrel cam, each having respective cam followers. The respective motions of the cam followers are superimposed on a stripper sleeve insert, which drives a core pin sleeve. The core pin sleeve is subjected to responsive three dimensional motion, allowing an internally threaded workpiece to be unscrewed from the core pin sleeve. The system does not require separate drives for the core pin sleeve, a single stripper plate drive being sufficient.

Abstract: An apparatus includes a fluid path, a coupling, and a nozzle. The fluid path is to carry a fluid including one or more microparticles. The coupling is located in the fluid path. The nozzle is located in the fluid path to move the fluid through a stagnant region located near the coupling. A method includes introducing a fluid including one or more microparticles into a fluid conduit including a coupling, aligning the fluid conduit near the coupling with a force field, and introducing the fluid includes delivering the one or more microparticles to a vasculature.

Abstract: An apparatus includes a fluid path, a coupling, and a nozzle. The fluid path is to carry a fluid including one or more microparticles. The coupling is located in the fluid path. The nozzle is located in the fluid path to move the fluid through a stagnant region located near the coupling.

Abstract: An apparatus and process for molding workpieces usable for consumer products. The workpieces may be injection molded with a cavity formed by a core pin and have an undercut, such as internal threads, in the cavity. The apparatus has a drive system with a stripper plate mounted for alternatingly forward and retracting axial movement. The stripper plate is axially driven and drives a stripper sleeve barrel cam and a core pin base barrel cam, each having respective cam followers. The respective motions of the cam followers are superimposed on a stripper sleeve insert, which drives a core pin sleeve. The core pin sleeve is subjected to responsive three-dimensional motion, allowing an internally threaded workpiece to be unscrewed from the core pin sleeve. The system does not require separate drives for the core pin sleeve and further allows each mold cavity/core pin combination in a mold half to be unique.

Abstract: The present invention relates to a method for increasing leakage resistance in a closed, pressurized system. The method involves providing a closed system including a container sealed with a septum having a top surface with an exposed section, which is maintained under a positive pressure of at least about 5 psig. A contact surface of a hard component is fixedly placed adjacent to or in contact with at least a portion of a border section or a central section of the exposed section of the septum, or both, to reduce the size of any bulge or deformation formed in the exposed section of the septum. The present invention also relates to a kit for increasing leakage resistance in a closed, pressurized system, which includes the hard component.

Abstract: An apparatus and process for molding workpieces usable for consumer products. The workpieces may be injection molded with a cavity formed by a core pin and have an undercut, such as internal threads, in the cavity. The apparatus has a drive system with a stripper plate mounted for alternatingly forward and retracting axial movement. The stripper plate is axially driven and drives a stripper sleeve barrel cam and a core pin base barrel cam, each having respective cam followers. The respective motions of the cam followers are superimposed on a stripper sleeve insert, which drives a core pin sleeve. The core pin sleeve is subjected to responsive three dimensional motion, allowing an internally threaded workpiece to be unscrewed from the core pin sleeve. The system does not require separate drives for the core pin sleeve, a single stripper plate drive being sufficient and further allows each mold cavity/core pin combination in a mold half to be unique.

Abstract: An apparatus and process for molding workpieces usable for consumer products. The workpieces may be injection molded with a cavity formed by a core pin and have an undercut, such as internal threads, in the cavity. The apparatus has a drive system with a stripper plate mounted for alternatingly forward and retracting axial movement. The stripper plate is axially driven and drives a stripper sleeve barrel cam and a core pin base barrel cam, each having respective cam followers. The respective motions of the cam followers are superimposed on a stripper sleeve insert, which drives a core pin sleeve. The core pin sleeve is subjected to responsive three dimensional motion, allowing an internally threaded workpiece to be unscrewed from the core pin sleeve. The system does not require separate drives for the core pin sleeve, a single stripper plate drive being sufficient and further allows each mold cavity/core pin combination in a mold half to be unique.

Abstract: The present invention relates to a method for increasing leakage resistance in a closed, pressurized system. The method involves providing a closed system including a container sealed with a septum having a top surface with an exposed section, which is maintained under a positive pressure of at least about 5 psig. A contact surface of a hard component is fixedly placed adjacent to or in contact with at least a portion of a border section or a central section of the exposed section of the septum, or both, to reduce the size of any bulge or deformation formed in the exposed section of the septum. The present invention also relates to a kit for increasing leakage resistance in a closed, pressurized system, which includes the hard component.

Abstract: The present invention relates to a method for increasing leakage resistance in a closed, pressurized system. The method involves providing a closed system including a container sealed with a septum having a top surface with an exposed section, which is maintained under a positive pressure of at least about 5 psig. A contact surface of a hard component is fixedly placed adjacent to or in contact with at least a portion of a border section or a central section of the exposed section of the septum, or both, to reduce the size of any bulge or deformation formed in the exposed section of the septum. The present invention also relates to a kit for increasing leakage resistance in a closed, pressurized system, which includes the hard component.

Abstract: A method of forming a multi-layer, co-injection molded article is disclosed. In an embodiment inner, middle, and outer layers of a polymer material are co-injected, and the velocity of the co-injection of the inner, middle, and outer layers are controlled. In embodiments of the method, the velocity of the co-injecting is less than about 0.390 inch/second. With embodiments, the articles may be formed from polyethylene terephthalate (PET). Articles, such as preforms, that are formed from a co-injection process, in which velocity is controlled, are also disclosed.

Abstract: An apparatus includes a fluid path, a coupling, and a nozzle. The fluid path is to carry a fluid including one or more microparticles. The coupling is located in the fluid path. The nozzle is located in the fluid path to move the fluid through a stagnant region located near the coupling.

Abstract: The present invention relates to a method for increasing leakage resistance in a closed, pressurized system. The method involves providing a closed system including a container sealed with a septum having a top surface with an exposed section, which is maintained under a positive pressure of at least about 5 psig. A contact surface of a hard component is fixedly placed adjacent to or in contact with at least a portion of a border section or a central section of the exposed section of the septum, or both, to reduce the size of any bulge or deformation formed in the exposed section of the septum. The present invention also relates to a kit for increasing leakage resistance in a closed, pressurized system, which includes the hard component.

Abstract: An apparatus includes a fluid path, a coupling, and a nozzle. The fluid path is to carry a fluid including one or more microparticles. The coupling is located in the fluid path. The nozzle is located in the fluid path to move the fluid through a stagnant region located near the coupling.

Abstract: An apparatus includes a fluid path, a coupling, and a nozzle. The fluid path is to carry a fluid including one or more microparticles. The coupling is located in the fluid path. The nozzle is located in the fluid path to move the fluid through a stagnant region located near the coupling.

Abstract: In one embodiment, a composition comprises a microparticle including a radioactive isotope and an imageable element. In another embodiment, a method includes forming a microparticle including a target isotope and an enriched paramagnetic isotope, and transforming the target isotope into a radioactive isotope. In yet another embodiment, an apparatus includes an imaging system to image a subject; and a radioactive microparticle suitable for infusion into the subject for imaging by the imaging system and including an enriched paramagnetic isotope that is enriched to reduce generation of radioactive impurities while maintaining or improving imaging sensitivity.

Abstract: An apparatus includes a fluid path, a coupling, and a nozzle. The fluid path is to carry a fluid including one or more microparticles. The coupling is located in the fluid path. The nozzle is located in the fluid path to move the fluid through a stagnant region located near the coupling.

Abstract: The side wall portion of a plastic article, as a plastic container, is opaque and includes a transparent portion, as a view stripe. The opaque portion limits viewing the inside of the article, whereas the transparent portion permits viewing the inside of the article therethrough. A method for forming the plastic article is also disclosed.

Abstract: The side wall portion of a plastic article, as a plastic container, is opaque and includes a transparent portion, as a view stripe. The opaque portion limits viewing the inside of the article, whereas the transparent portion permits viewing the inside of the article therethrough. A method for forming the plastic article is also disclosed.

Abstract: The container includes a hollow body of plastic material having a lower supporting base, a sidewall extending upwardly from the base, a shoulder portion extending upwardly from the sidewall and an upper neck portion with an opening therein extending upwardly from the shoulder portion. The neck portion includes at least one engagement surface which fits together with at least one engagement surface on a separately formed handle to form at least one projection seated in at least one groove.