Abstract: The present disclosure relates to indolinyl compounds. The present disclosure further relates to compounds that inhibit viral helicase-primase. The present disclosure further relates to the use of the compounds for the preparation a medicament for the treatment of diseases and/or condition through inhibiting viral helicase-primase. The present disclosure also relates to use of those compounds in the treatment of viral infections. The present disclosure further relates to intermediates for its preparation and to pharmaceutical compositions containing those compounds.

Abstract: A dual telemetric coiled tubing running string for disposing a bottom hole assembly into a wellbore. The dual telemetric coiled tubing running string includes a string of coiled tubing which defines a flowbore along its length, an electrical wire conduit disposed within the flowbore, and an optic fiber disposed within the flowbore.

Abstract: A telemetry system for a resource exploration and recovery system including a tubular defining a flow bore, and a superconductor wire disposed within the flow bore. A resource exploration and recovery system including a first system, a second system fluidically connected to the first system, and a telemetry system operatively connected to the first system extending into the second system, the telemetry system including a tubular defining a flow bore, and a superconductor wire disposed within the flow bore.

Abstract: A dual telemetric coiled tubing running string for disposing a bottom hole assembly into a wellbore.

Abstract: Electrically-operated downhole tools are run into a wellbore on a coiled tubing string which includes tube-wire that is capable of carrying power and data along its length. During operation, a downhole tool is provided power from surface using the tube-wire. Downhole data is provided to the surface via tube-wire.

Abstract: A telemetry system for a resource exploration and recovery system including a tubular defining a flow bore, and a superconductor wire disposed within the flow bore. A resource exploration and recovery system including a first system, a second system fluidically connected to the first system, and a telemetry system operatively connected to the first system extending into the second system, the telemetry system including a tubular defining a flow bore, and a superconductor wire disposed within the flow bore.

Abstract: Arrangements and methods for acid tunneling and fracturing within a wellbore. Acid is flowed into a wellbore to form a lateral tunnel which extends radially outwardly from the main wellbore. Thereafter, a fracturing bottom hole assembly is run into the lateral tunnel and isolated. Acid is then injected into the lateral tunnel to fracture portions of the formation radially surrounding the lateral tunnel.

Abstract: Arrangements for transmitting electrical operating power to a downhole electrically operated tool via a dual-walled conductive running string.

Abstract: A milling assembly for use in milling away an object in a wellbore. A milling bottom hole assembly is run in on a Telecoil® running string and includes a rechargeable power section which is recharged via tube-wire in the running string. The milling bottom hole assembly also includes a sensor section which measures tension, compression and torque experienced by the running string during milling.

Abstract: A re-fracturing method involves placement and centralization of a liner string that has shaped charges at predetermined locations that are externally isolated with packers. The shaped charges can be set off in a desired order and re-fracturing can then take place in new locations. In a bottom up order for perforating sequentially larger balls can be landed on seats and developed pressure or component movement generated by applying pressure can be used to set a shaped charge and isolate portions of the borehole below. The balls and even the seats can be later milled out or just allowed to disintegrate or dissolve with well fluids that are present or later added to clear the liner for subsequent production. Alternatively, the liner could be removed by release of the packers before production or injection begins.

Abstract: Electrically-operated downhole tools are run into a wellbore on a coiled tubing string which includes tube-wire that is capable of carrying power and data along its length. During operation, a downhole tool is provided power from surface using the tube-wire. Downhole data is provided to the surface via tube-wire.

Abstract: Electrically-operated downhole tools are run into a wellbore on a coiled tubing string which includes tube-wire that is capable of carrying power and data along its length. During operation, a downhole tool is provided power from surface using the tube-wire. Downhole data is provided to the surface via tube-wire.

Abstract: An acid tunneling system for forming lateral tunnels from a central wellbore. The acid tunneling system includes an acid tunneling tool having an acid injection nozzle which can be steered and oriented in response to downhole parameters that are detected and sent to surface in real time.

Abstract: Arrangements for transmitting electrical operating power to a downhole electrically operated tool via a dual-walled conductive running string.

Abstract: A method of increasing a roughness of coiled tubing injector blocks that includes providing a pair of gripper blocks each having a gripper surface configured to grip coiled tubing within an injector head and increasing a first roughness on the gripping surfaces to a second roughness. A coating may be applied to the gripping surfaces to increase the roughness. The coating may be chromium carbide, molybdenum boride, iron boride, titanium boride, or a transitional metal boride. The gripping surfaces may be treated to increase the roughness to a second roughness. The gripping surfaces may be blasted by abrasives or shot peened to increase the roughness. The second roughness may be greater than 20 ?m. A system to inject coiled tubing into a wellbore may include an injector head, coiled tubing, and at least two gripper blocks having a gripping surface with a roughness of at least 20 ?m.

Abstract: Hydrocarbon production from subterranean formations is stimulated by heating. A dual-walled coiled tubing radio frequency heating arrangement is described that can be disposed into a wellbore and energized to heat the surrounding formation.

Abstract: A system and method for forming tunnels in formation radially surrounding a wellbore.

Abstract: A wireless data communication system within a tunneling tool used to form subterranean tunnels. The wireless data communication system is useful to provide real time data relating to tunneling and for controlling or adjusting the tunneling process.

Abstract: A milling assembly for use in milling away an object in a wellbore. A milling bottom hole assembly is run in on a Telecoil® running string and includes a rechargeable power section which is recharged via tube-wire in the running string. The milling bottom hole assembly also includes a sensor section which measures tension, compression and torque experienced by the running string during milling.

Abstract: A matrix acidizing monitoring system wherein a sensor array is operably associated with a matrix acidizing bottom hole assembly and contains first and second sets of sensors that detect a matrix acidizing operational parameter at different times at one or more particular locations along the wellbore. This allows the effectiveness of the acidizing to be modeled.