Abstract: Aspects of the invention include systems and methods configured to checkpoint an application executing on a virtual machine. Aspects include receiving from a first thread executing on a virtual machine a call to a checkpoint application program interface (API) and suspending, by the virtual machine, execution of all threads other than the first thread. Aspects also includes executing, by the virtual machine, all application checkpoint hooks and executing, by the virtual machine, all virtual machine checkpoint hooks. Aspects further include creating one or more checkpoint image files.

Abstract: Method and systems for preparing and analyzing a DNA sample from a subject are provided herein. Also provided are methods and systems for obtaining, analyzing, and manipulating genomic and proteomic sequence data. In particular, methods and systems provided herein involve transformation of raw genetic or proteomic sequence into a compressed data set and transmission of the compressed data set using a fixed binary encoding scheme capable of compressing the data by up to 75%. An interface is in communication with the compression module and configured to display transmitted genomic and proteomic sequence data.

Abstract: A surgical instrument includes a body, a shaft assembly extending distally from and rotatably coupled to the body, an end effector extending distally from the shaft assembly, a fiber optic cable, and a rotary coupling assembly. The end effector may rotate with the shaft assembly relative to the body. The end effector includes a sensor assembly. The fiber optic cable extends proximally from the sensor assembly, along the shaft assembly, and into the body. The fiber optic cable includes a distal portion that rotates with the end effector, a proximal portion associated with the body, and a coiled portion interposed between the distal portion and the proximal portion. The rotary coupling assembly includes a handle-side body and a shaft-side body. The rotary coupling assembly can radially expand and contract the coiled portion of the fiber optic cable in response to relative rotation between the handle-side body and the shaft-side body.

Abstract: A surgical system includes a surgical instrument, including a shaft assembly having a distal end and an end effector at the distal end of the shaft assembly. The end effector includes a first jaw, a second jaw movably coupled relative to the first jaw for clamping tissue therebetween, and an optical sensor for detecting the tissue. The surgical system also includes a generator configured to supply a therapeutic energy to the first jaw or the second jaw, and a pass-through device configured to be connected between the surgical instrument and the generator. The pass-through device includes a therapeutic energy connector configured to operatively couple the generator to the surgical instrument for transmitting the therapeutic energy from the generator to the first jaw or the second jaw, and at least one optical component configured to transmit light to the optical sensor and to receive light from the optical sensor.

Abstract: A surgical instrument includes a shaft assembly having a distal end and an end effector at the distal end of the shaft assembly. The end effector includes a first jaw and a second jaw movably coupled relative to the first jaw for clamping tissue therebetween. The end effector also includes at least one lightbox for detecting the tissue. The at least one lightbox includes a housing having at least one optically transmissive surface configured to face the tissue. The at least one lightbox also includes at least one of an illuminating element or a light receiving element. The at least one of an illuminating element or a light receiving element is secured to the housing.

Abstract: An airfoil includes a first airfoil piece and a second airfoil piece that is bonded to the first airfoil piece at a joint. The first airfoil piece and the second airfoil piece are formed of aluminum alloys. At least one of the aluminum alloys is an aluminum alloy composition that has greater than 0.8% by weight of zinc. The joint includes a braze element of magnesium, zinc, or combinations thereof in a higher concentration than in other portions of the first airfoil piece and the second airfoil piece.

Abstract: An illustrative embodiment of a computer-implemented method for correlating artifacts between a versioned domain and an un-versioned domain, generates metadata having attributes of both of the versioned domain and the un-versioned domains, for an artifact in a set of artifacts; creates an instance using a specific version of a versioned artifact definition, wherein the instance comprises a first part directly created from the versioned artifact definition and a second part created from an un-versioned artifact definition; specifies linkages between a respective representation of the artifact in the versioned domain and the un-versioned domain; provides a set of facades through which a selected one of author, execute and update instances of the artifact is performed using either the versioned domain or the un-versioned domain; and correlates all versions of the artifact definition to a single un-versioned definition.

Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data. In some cases, a user interface is in communication with a system or device provided herein.

Abstract: An airfoil includes a first airfoil piece and a second airfoil piece that is bonded to the first airfoil piece at a joint. The first airfoil piece and the second airfoil piece are formed of aluminum alloys. At least one of the aluminum alloys is an aluminum alloy composition that has greater than 0.8% by weight of zinc. The joint includes a braze element of magnesium, zinc, or combinations thereof in a higher concentration than in other portions of the first airfoil piece and the second airfoil piece.

Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data.

Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data. In some cases, a user interface is in communication with a system or device provided herein.

Abstract: An airfoil includes a first airfoil piece and a second airfoil piece bonded to the first airfoil piece at a joint. The first airfoil piece and the second airfoil piece are formed of aluminum alloys. At least one of the aluminum alloys is an aluminum alloy composition that has greater than 0.8% by weight of zinc.

Abstract: A coated article comprising: a substrate; and a coating on the substrate comprising: a metallic matrix comprising, by weight: Al as a largest constituent; 3.0-6.0 Cr; 1.5-4.0 Mn; 0.1-3.5 Co; and 0.3-2.0 Zr; and a filler and optionally porosity.

Abstract: Dispersion strengthened aluminum-cerium-manganese alloys containing from about 0.05 to about 23.0 weight percent cerium and about 0.03 to about 9.5 weight percent manganese exhibit mechanical properties that make them useful alloys as a result of age hardening for extended periods at temperatures between 350° C. (662° F.) and 450° C. (842° F.).

Abstract: A composition comprises, in weight percent: Al as a largest constituent; 3.0-6.0 Cr; 1.5-4.0 Mn; 0.1-3.5 Co; and 0.3-2.0 Zr.

Abstract: A composition comprises, in weight percent: Al as a largest constituent; 3.0 6.0 Cr; 1.5 4.0 Mn; 0.1 3.5 Co; and 0.3 2.0 Zr.

Abstract: An airfoil includes an airfoil body that extends at least between leading and trailing edges, first and second sides, and radially inner and outer ends. The airfoil body includes an aluminum alloy that has a controlled crystallographic texture with respect to a predefined three-dimensional coordinate system. The airfoil can be used in the fan of a gas turbine engine.

Abstract: A dynamic compaction process comprises forming first and second preforms. Forming each preform includes utilizing a container having an interior and an exterior. Filling the interior of the container with a powder material; sealing the container; subjecting the exterior of the container to an instantaneous dynamic compaction, forming a solid powder metallurgy preform encased by the container. The container gets removed from each preform. The process includes inserting the first and second preforms in another container in a predefined pattern; the predefined pattern aligns the first and second preforms creating an interface. The process includes inserting a backstop against the predefined pattern in this container; subjecting the exterior of this container to an instantaneous dynamic compaction. The process includes bonding the first preform and second preform along the interface to form a component precursor; and removing the container from the precursor.

Abstract: The present disclosure provides techniques for analysis of genetic features. In particular, machine learning techniques can be used to analyze various statistical features in determining genetic features such as variants, markers, and traits, for example in a nucleotide sequence.

Abstract: A coated article comprising: a substrate; and a coating on the substrate comprising: a metallic matrix comprising, by weight: Al as a largest constituent; 3.0-6.0 Cr; 1.5-4.0 Mn; 0.1-3.5 Co; and 0.3-2.0 Zr; and a filler and optionally porosity.