Patents by Inventor Thomas James Farrell

Thomas James Farrell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC ANTIGEN RECEPTOR COMPRISING AN ANTI-HER2 ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF AND NATURAL KILLER CELLS COMPRISING THE SAME
    Publication number: 20250073264
    Abstract: Provided herein, among other things, are polynucleotides comprising a nucleic acid encoding an anti-human epidermal growth factor receptor 2 (HER2) chimeric antigen receptor (CAR) and natural killer cells expressing the polynucleotides.
    Type: Application
    Filed: April 6, 2022
    Publication date: March 6, 2025
    Inventors: Hoyong LIM, Sungyoo CHO, Yu Kyeong HWANG, Eunji CHOI, Miyoung JUNG, Eunsol LEE, Hansol KIM, Peter FLYNN, Jason B. LITTEN, Thomas James FARRELL, John Kin Chuan LIM, Heather Karen RAYMON, Lisa GUERRETTAZ
  • TREATMENT OF CANCER WITH NK CELLS AND MULTISPECIFIC ENGAGERS
    Publication number: 20240424099
    Abstract: Provided herein are methods for treating a patient suffering from cancer with an natural killer (NK) cell with a KIR-B haplotype and expresses a CD16 molecule, and a bispecific antibody which binds CD16 and CD30, along with methods of producing NK cell populations, and pharmaceutical compositions comprising the NK cells and bispecific antibodies.
    Type: Application
    Filed: November 3, 2022
    Publication date: December 26, 2024
    Inventors: Peter FLYNN, Jason B. LITTEN, Thomas James FARRELL, Heather Karen RAYMON, Srinivas Sai SOMANCHI, Lisa GUERRETTAZ, Thorsten GRAEF, Joachim KOCH, Jens PAHL, Bokyung MIN, Hyojin KIM, Sanghyun LEE
  • CHIMERIC ANTIGEN RECEPTOR COMPRISING AN ANTI-CD19 ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF AND NATURAL KILLER CELLS COMPRISING THE SAME
    Publication number: 20240366663
    Abstract: Provided herein, among other things, are anti-CD 19 chimeric antigen receptor (CAR)s and natural killer cells expressing the same.
    Type: Application
    Filed: April 6, 2022
    Publication date: November 7, 2024
    Inventors: Yusun KIM, Sungyoo CHO, Yu Kyeong HWANG, Peter FLYNN, Jason B. LITTEN, Thomas James FARRELL, John Kin Chuan LIM
  • TREATMENT OF CANCER WITH NK CELLS AND AN EGFR TARGETED ANTIBODY
    Publication number: 20240366664
    Abstract: Provided herein are, among other things, methods for treating a patient suffering from an EGFR+ cancer.
    Type: Application
    Filed: April 6, 2022
    Publication date: November 7, 2024
    Inventors: Yusun KIM, Sungyoo CHO, Yu Kyeong HWANG, Bokyung MIN, Bitna YANG, Eunji KIM, Peter FLYNN, Jason B. LITTEN, Thomas James FARRELL, John Kin Chuan LIM, Mili MANDAL
  • TREATMENT OF CANCER WITH NK CELLS AND A HER2 TARGETED ANTIBODY
    Publication number: 20240197778
    Abstract: Provided herein are, among other things, methods for treating a patient suffering from a HER2+ cancer.
    Type: Application
    Filed: April 6, 2022
    Publication date: June 20, 2024
    Inventors: Yusun KIM, Sungyoo CHO, Yu Kyeong HWANG, Bokyung MIN, Bitna YANG, Eunji KIM, Peter FLYNN, Jason B. LITTEN, Thomas James FARRELL, John Kin Chuan LIM, Mili MANDAL
  • TREATMENT OF CANCER WITH NK CELLS AND A CD20 TARGETED ANTIBODY
    Publication number: 20240180962
    Abstract: Provided herein are, among other things, methods for treating a patient suffering from a CD20+ cancer.
    Type: Application
    Filed: April 6, 2022
    Publication date: June 6, 2024
    Inventors: Sungyoo CHO, Yu Kyeong HWANG, Eunji CHOI, Miyoung JUNG, Hoyong LIM, Eunsol LEE, Hansol KIM, Peter FLYNN, Jason B. LITTEN, Thomas James FARRELL, John Kin Chuan LIM, Mili MANDAL
  • TREATMENT OF CANCER WITH NK CELLS AND A CD38-TARGETED ANTIBODY
    Publication number: 20240115704
    Abstract: Provided herein are, among other things, methods for treating a patient suffering from a CD38+ cancer.
    Type: Application
    Filed: April 6, 2022
    Publication date: April 11, 2024
    Inventors: Peter FLYNN, Jason B. LITTEN, Thomas James FARRELL, John Kin Chuan LIM, Mili MANDAL, Srinivas Sai SOMANCHI, Yusun KIM, Sungyoo CHO, Yu Kyeong HWANG
  • EXPANDED AND STIMULATED NATURAL KILLER CELLS
    Publication number: 20240060046
    Abstract: Provided here, amongst other things, are populations of expanded and stimulated natural killer cells, pharmaceutical compositions comprising populations of expanded and stimulated natural killer cells, and methods of expanding and stimulating natural killer cells
    Type: Application
    Filed: December 16, 2021
    Publication date: February 22, 2024
    Inventors: Seungryel Han, Bokyung Min, Sungyoo Cho, Yu Kyeong Hwang, Jung Hyun Her, Yusun Kim, Eunji Kim, Hyojin Kim, Bitna Yang, Peter Flynn, Jason B. Litten, Thomas James Farrell, John Kin Chuan Lim, Mili Mandal
  • TREATMENT OF CANCER WITH NK CELLS AND A CD20 TARGETED ANTIBODY
    Publication number: 20240000840
    Abstract: Provided herein are, among other things, methods for treating a patient suffering from a CD20+ cancer
    Type: Application
    Filed: December 16, 2021
    Publication date: January 4, 2024
    Inventors: Yu Kyeong Hwang, Jung Hyun Her, Yusun Kim, Eunji Kim, Hyojin Kim, Bitna Yang, Bokyung Min, Peter Flynn, Jason B. Litten, Thomas James Farrell, John Kin Chuan Lim, Mili Mandal