Patents by Inventor Thomas Jay Lowery, JR.

Thomas Jay Lowery, JR. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NMR METHODS AND SYSTEMS FOR THE RAPID DETECTION OF BACTERIA
    Publication number: 20240026415
    Abstract: The invention features methods, panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.
    Type: Application
    Filed: October 25, 2022
    Publication date: January 25, 2024
    Inventors: Ulrich Hans THOMANN, Lori Anne NEELY, Heidi Susanne GIESE, Jessica Ann TOWNSEND, Rahul Krishan DHANDA, Thomas Jay LOWERY, JR., Urvi VED, Brendan MANNING, Nu Ai PHUNG, Joanne Lawton GARVER, Benjamin B. STONE
  • Containers for agitation of liquid samples and methods of use thereof
    Patent number: 11666872
    Abstract: The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: June 6, 2023
    Assignee: T2 Biosystems, Inc.
    Inventors: Adam Suchocki, Mark John Audeh, Matthew Blanco, James Franklin Chepin, Vasiliki Demas, Marilyn Lee Fritzemeier, Thomas Jay Lowery, Jr., Michael Min, Lori Anne Neely, Charles William Rittershaus, Hwa-Tang Wang, Parris Wellman
  • METHODS OF IMPLANTING ENGINEERED TISSUE CONSTRUCTS
    Publication number: 20230132318
    Abstract: The present disclosure provides engineered tissue constructs having a population of cells, such as hepatocytes and stromal cells, and methods of making and using the same (e.g., for treating a disease or disorder, such as acute liver failure, a urea cycle disorder, or hyperbilirubinemia (e.g., in a subject having Crigler-Najjar syndrome) in a human subject in need thereof).
    Type: Application
    Filed: May 27, 2022
    Publication date: April 27, 2023
    Inventors: Laura LANDE-DINER, Howard TAKIFF, Amanda CHEN, Arnav CHHABRA, Thomas Jay LOWERY, JR., Morgan JAMIEL, Alison HAYWARD, Timothy Alfred NORMAN, JR., Joseph E. MARTURANO
  • NMR methods and systems for the rapid detection of bacteria
    Patent number: 11519016
    Abstract: The invention features methods panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: December 6, 2022
    Assignee: T2 Biosystems, Inc.
    Inventors: Ulrich Hans Thomann, Lori Anne Neely, Heidi Susanne Giese, Jessica Ann Townsend, Rahul Krishan Dhanda, Thomas Jay Lowery, Jr., Urvi Ved, Brendan Manning, Nu Ai Phung, Joanne Lawton Garver, Benjamin B. Stone
  • NMR METHODS AND SYSTEMS FOR THE RAPID DETECTION OF TICK-BORNE PATHOGENS
    Publication number: 20220228199
    Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.
    Type: Application
    Filed: April 5, 2022
    Publication date: July 21, 2022
    Inventors: Ulrich Hans THOMANN, Lori Anne NEELY, Rahul Krishan DHANDA, Frédéric SWEENEY, Thomas Jay LOWERY, JR., Jessica Ann TOWNSEND, Jessica Lee SNYDER, Heidi Susanne GIESE, Cheryl Ann BANDOSKI-GRALINSKI, Daniella Lynn LOGAN
  • NMR methods and systems for the rapid detection of tick-borne pathogens
    Patent number: 11326213
    Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: May 10, 2022
    Assignee: T2 Biosystems, Inc.
    Inventors: Ulrich Hans Thomann, Lori Anne Neely, Rahul Krishan Dhanda, Frédéric Sweeney, Thomas Jay Lowery, Jr., Jessica Ann Townsend, Jessica Lee Snyder, Heidi Susanne Giese, Cheryl Ann Bandoski-Gralinski, Daniella Lynn Logan
  • METHODS AND SYSTEMS FOR AMPLIFICATION IN COMPLEX SAMPLES
    Publication number: 20210002715
    Abstract: The invention features methods, systems, and cartridges for amplification of target nucleic acids in complex samples, for example, whole blood. The invention also features diagnostic and therapeutic methods based on amplification of target nucleic acids characteristic of pathogens present in complex samples containing cells and/or cell debris, for example, whole blood.
    Type: Application
    Filed: April 12, 2017
    Publication date: January 7, 2021
    Inventors: Ulrich Hans THOMANN, Jessica Lee SNYDER, Thomas Jay LOWERY, Jr.
  • NMR METHODS AND SYSTEMS FOR THE RAPID DETECTION OF CANDIDA SPECIES
    Publication number: 20200291488
    Abstract: The invention features methods, systems, and panels for rapid detection of Candida species (e.g., Candida auris, Candida lusitaniae, Candida haemulonii, Candida duobushaemulonii, and Candida pseudohaemulonii) in biological samples (e.g., whole blood) and environmental samples (e.g., environmental swabs, e.g., surface swabs), and for diagnosis and monitoring of diseases, including Candidiasis and sepsis.
    Type: Application
    Filed: May 17, 2018
    Publication date: September 17, 2020
    Inventors: Brendan John MANNING, Jessica Lee SNYDER, Benjamin Nguyen CHANG, Trissha Ritsue HIGA, Robert Patrick SHIVERS, Yin Shan Cathy WONG, Thomas Jay LOWERY, Jr., Urvi VED, Daniel GAMERO
  • CONTAINERS FOR AGITATION OF LIQUID SAMPLES AND METHODS OF USE THEREOF
    Publication number: 20200261873
    Abstract: The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.
    Type: Application
    Filed: October 21, 2019
    Publication date: August 20, 2020
    Inventors: Adam SUCHOCKI, Mark John AUDEH, Matthew BLANCO, James Franklin CHEPIN, Vasiliki DEMAS, Marilyn Lee FRITZEMEIER, Thomas Jay LOWERY, JR., Michael MIN, Lori Anne NEELY, Charles William RITTERSHAUS, Hwa-Tang WANG, Parris WELLMAN
  • NMR methods for monitoring blood clot formation
    Patent number: 10697984
    Abstract: The invention features a method of monitoring a clotting process by measuring a signal characteristic of the NMR relaxation of water in a sample undergoing clotting to produce NMR relaxation data and determining from the NMR relaxation data a magnetic resonance parameter of water in the sample characteristic of the clots being formed.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: June 30, 2020
    Assignee: T2 Biosystems, Inc.
    Inventors: Thomas Jay Lowery, Jr., Vyacheslav Papkov, Walter W. Massefski, Jr., Rahul K. Dhanda, Edward Chris Thayer
  • NMR methods for endotoxin analysis
    Patent number: 10620205
    Abstract: The invention features a method of monitoring a clotting process by measuring a signal characteristic of the NMR relaxation of water in a sample undergoing endotoxi-induced clotting to produce NMR relaxation data and determining from the NMR relaxation data a magnetic resonance parameter of water in the sample characteristic of the level of endotoxin present in the sample.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: April 14, 2020
    Assignee: T2 Biosystems, Inc.
    Inventors: Rahul K. Dhanda, Vyacheslav Papkov, Thomas Jay Lowery, Jr.
  • Containers for agitation of liquid samples and methods of use thereof
    Patent number: 10486118
    Abstract: The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: November 26, 2019
    Assignee: T2 Biosystems, Inc.
    Inventors: Adam Suchocki, Mark John Audeh, Matthew Blanco, James Franklin Chepin, Vasiliki Demas, Marilyn Lee Fritzemeier, Thomas Jay Lowery, Jr., Michael Min, Lori Anne Neely, Charles William Rittershaus, Hwa-Tang Wang, Parris Wellman
  • NMR METHODS AND SYSTEMS FOR THE RAPID DETECTION OF BACTERIA
    Publication number: 20190071707
    Abstract: The invention features methods panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.
    Type: Application
    Filed: January 20, 2017
    Publication date: March 7, 2019
    Inventors: Ulrich Hans THOMANN, Lori Anne NEELY, Heidi Susanne GIESE, Jessica Ann TOWNSEND, Rahul Krishan DHANDA, Thomas Jay LOWERY, Jr., Urvi VED, Brendan MANNING, Nu Ai PHUNG, Joanne Lawton GARVER, Benjamin B. STONE
  • RAPID ANTIMICROBIAL SUSCEPTIBILITY TESTING USING HIGH-SENSITIVITY DIRECT DETECTION METHODS
    Publication number: 20190032104
    Abstract: The invention features methods, panels, cartridges, kits, and systems for rapid and sensitive detection and identification of pathogens and determination of the pathogen's susceptibility to antimicrobial agents for diagnosis and treatment of disease, including bloodstream infection (e.g., bacteremia and fungemia), and sepsis.
    Type: Application
    Filed: January 20, 2017
    Publication date: January 31, 2019
    Applicant: T2 Biosystems, Inc.
    Inventors: Thomas Jay LOWERY, JR., Michael Andy PFALLER, Rahul Krishan DHANDA, John J. MCDONOUGH, Glenn MAGNUSON, Lori Anne NEELY, Ulrich Hans THOMANN, William Coulter HARRIS, Justin Layne BLACK
  • Magnetic nanosensor compositions and bioanalytical assays therefor
    Patent number: 10184907
    Abstract: Disclosed are magnetic nanosensors or transducers that permit measurement of a physical parameter in an analyte via magnetic reasonance measurements, in particular of non-agglomerative assays. More particularly, in certain embodiments, the invention relates to designs of nanoparticle reagents and responsive polymer coated magnetic nanoparticles. Additionally provided are methods of use of nanoparticle reagents and responsive polymer coated magnetic nanoparticles for the detection of a stimulus or an analyte with NMR detectors.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: January 22, 2019
    Assignee: T2 Biosystems, Inc.
    Inventors: Thomas Jay Lowery, Jr., James Joseph Koziarz, Douglas Adam Levinson, David A. Berry, Tuan A. Elstrom, Sonia Kumar, Mark John Audeh
  • SYSTEMS AND METHODS FOR MULTIPLEXED HEMOSTASIS TEST PANELS
    Publication number: 20180188195
    Abstract: The invention features a diagnostic platform utilizing T2 magnetic resonance to directly measure integrated reactions in whole blood samples such as clotting, fibrinogen, clot contraction, and fibrinolysis to provide a comprehensive assessment of hemostatic parameters on a single instrument in minutes. The methods of the invention can be performed with less than 1 ml of blood and minimal sample handling.
    Type: Application
    Filed: June 27, 2016
    Publication date: July 5, 2018
    Inventors: Eugenio DAVISO, Lucius (Tad) FOX, Thomas Jay LOWERY, Jr., Joseph MARTURANO, Vyacheslav PAPKOV, Al SCHROFF, Roger SMITH, Zhixiang LUO
  • NMR METHODS AND SYSTEMS FOR THE RAPID DETECTION OF TICK-BORNE PATHOGENS
    Publication number: 20180171388
    Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.
    Type: Application
    Filed: January 21, 2016
    Publication date: June 21, 2018
    Inventors: Ulrich Hans THOMANN, Lori Anne NEELY, Rahul Krishan DHANDA, Frédéric SWEENEY, Thomas Jay LOWERY, JR., Jessica Ann TOWNSEND, Jessica Lee SNYDER, Heidi Susanne GIESE, Cheryl Ann BANDOSKI-GRALINSKI, Daniella Lynn LOGAN
  • NMR METHODS FOR MONITORING BLOOD CLOT FORMATION
    Publication number: 20180113141
    Abstract: The invention features a method of monitoring a clotting process by measuring a signal characteristic of the NMR relaxation of water in a sample undergoing clotting to produce NMR relaxation data and determining from the NMR relaxation data a magnetic resonance parameter of water in the sample characteristic of the clots being formed.
    Type: Application
    Filed: September 27, 2017
    Publication date: April 26, 2018
    Inventors: Thomas Jay LOWERY, Jr., Vyacheslav PAPKOV, Walter W. MASSEFSKI, Jr., Rahul K. DHANDA, Edward Chris THAYER
  • METHODS FOR BLOOD TYPING AND ANTIBODY SCREENING
    Publication number: 20170315141
    Abstract: The invention features systems and methods for the detection of analytes, particularly antigens, complement, and antibodies present in blood. The invention features a system for the detection of antigens, complement, and antibodies on the surface of RBCs and circulating antibodies in the blood.
    Type: Application
    Filed: November 12, 2015
    Publication date: November 2, 2017
    Inventors: Thomas Jay LOWERY, JR., Vyacheslav PAPKOV, Walter W. MASSEFSKI, JR.
  • NMR methods for monitoring blood clot formation
    Patent number: 9797914
    Abstract: The invention features a method of monitoring a clotting process by measuring a signal characteristic of the NMR relaxation of water in a sample undergoing clotting to produce NMR relaxation data and determining from the NMR relaxation data a magnetic resonance parameter of water in the sample characteristic of the clots being formed.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: October 24, 2017
    Assignee: T2 Biosystems, Inc.
    Inventors: Thomas Jay Lowery, Jr., Vyacheslav Papkov, Walter W. Massefski, Jr., Rahul K. Dhanda, Edward Chris Thayer