Patents by Inventor Thomas Jay Webster

Thomas Jay Webster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Titanium Dioxide Coatings for Medical Devices Made by Atomic Layer Deposition
    Publication number: 20220072198
    Abstract: Implantable medical devices coated with multiple atomic layers of amorphous titanium dioxide applied by atomic layer deposition have improved mammalian cell adhesion and inhibition of bacterial growth. Thickness of the coating can be used to tune resorption of bioresorbable vascular scaffolds for treatments of cardiovascular disease.
    Type: Application
    Filed: January 10, 2020
    Publication date: March 10, 2022
    Inventors: Thomas Jay WEBSTER, Paria GHANNADIAN, Fan YANG, James Walter MOXLEY
  • Amphiphilic Peptide Nanoparticles for Use as Hydrophobic Drug Carriers and Antibacterial Agents
    Publication number: 20170202783
    Abstract: Nanoparticulate carrier formulations are useful to solubilize, deliver, and target hydrophobic drugs for treating diseases including cancer and bacterial infections. The formulations contain amphiphilic peptides having a hydrophobic portion and a positively charged hydrophilic portion. The peptides self-associate at nonacidic pH to form mi-celles with a spherical nanoparticle morphology. The hydrophobic core of the nano-particles encapsulates hydrophobic drugs, including antitumor agents, increasing their solubility in water and allowing them to be targeted, for example, to cancer cells. The positively charged surface of the nanoparticles, together with an optional targeting moiety such as an RGD peptide, allows the nanoparticles to bind selectively to mammalian cells and bacterial cells, including cancer cells that overexpress integrin receptors.
    Type: Application
    Filed: July 8, 2015
    Publication date: July 20, 2017
    Inventors: Run CHANG, Linlin SUN, Thomas Jay WEBSTER, Gujie MI
  • BIOCOMPATIBLE NANOPHASE MATERIALS
    Publication number: 20160151543
    Abstract: Provided is an implantable composition having a metallic component, the metallic component being made of metal selected titanium, a titanium alloy, and CoCrMo, wherein the metal is formed from particles of nanophase powder having at least one dimension that is in the range of 1 to 2500 nm. Methods of making the implantable composition are also provided.
    Type: Application
    Filed: February 1, 2016
    Publication date: June 2, 2016
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Thomas Jay WEBSTER, Karen Marie HABERSTROH, Saba CHOUDHARY
  • Material and method for promoting tissue growth
    Patent number: 7833283
    Abstract: A composition for promoting tissue growth which includes a material for placing in contact with animal tissue.
    Type: Grant
    Filed: August 15, 2002
    Date of Patent: November 16, 2010
    Assignee: Purdue Research Foundation
    Inventors: Thomas Jay Webster, Karen Marie Haberstroh
  • Biocompatable Nanophase Materials
    Publication number: 20080249607
    Abstract: A metallic substance having a nanophase surface.
    Type: Application
    Filed: September 20, 2006
    Publication date: October 9, 2008
    Inventors: Thomas Jay Webster, Karen Marie Haberstroh, Saba Choudhary
  • Material and method for promoting tissue growth
    Publication number: 20040038063
    Abstract: A composition for promoting tissue growth which includes a material for placing in contact with animal tissue.
    Type: Application
    Filed: February 19, 2003
    Publication date: February 26, 2004
    Inventors: Thomas Jay Webster, Karen Marie Haberstroh