Abstract: An illuminating wire medical device may include an elongate flexible housing and an illuminating fiber and a core wire extending through at least part of the housing, the core wire providing desired pushability and torquability. The illuminating device may further include a connector assembly cooperating with the illuminating fiber to accommodate changes in length, to absorb forces applied during use of the device and to channel errant light away from the illuminating fibers of the device.

Abstract: A method and system for providing a consistent flow documents and data content across different organizational units of a company or agency where the documents and data come from different enterprise systems and data stores but are related to linked processes that share models for organizing the content in the business context and in a format that enables a user to relate the content to the process step or steps they are performing. The system includes a network service that enables a configuration utility to automatically discover the objects and metadata and provides for a mapping of selected fields of the metadata to regions displayed in the user interface view with provision for filtering the data by mapping selected fields to a user input form. Thereby, a business analyst can create solutions without writing and maintaining complex program logic for each combination of presentation environment, enterprise system and data store.

Abstract: A method and system for providing a consistent flow documents and data content across different organizational units of a company or agency where the documents and data come from different enterprise systems and data stores but are related to linked processes that share models for organizing the content in the business context and in a format that enables a user to relate the content to the process step or steps they are performing. The system includes a network service that enables a configuration utility to automatically discover the objects and metadata and provides for a mapping of selected fields of the metadata to regions displayed in the user interface view with provision for filtering the data by mapping selected fields to a user input form. Thereby, a business analyst can create solutions without writing and maintaining complex program logic for each combination of presentation environment, enterprise system and data store.

Abstract: A method and system for providing a consistent flow documents and data content across different organizational units of a company or agency where the documents and data come from different enterprise systems and data stores but are related to linked processes that share models for organizing the content in the business context and in a format that enables a user to relate the content to the process step or steps they are performing. The system includes a network service that enables a configuration utility to automatically discover the objects and metadata and provides for a mapping of selected fields of the metadata to regions displayed in the user interface view with provision for filtering the data by mapping selected fields to a user input form. Thereby, a business analyst can create solutions without writing and maintaining complex program logic for each combination of presentation environment, enterprise system and data store.

Abstract: A bipolar, plasma-generating electrosurgical apparatus and system wherein the return electrode is enclosed within an electrosurgical shaft, and the active electrode is located on the outside surface of the shaft such that in treating the tissue, the tissue is exposed to plasma generated on the active electrode, but is minimally exposed to electric fields generated between the active and return electrodes. Due to the configuration of the electrodes, electric fields generated between the electrodes are directed away from the target tissue and inwardly towards the return electrode within the shaft, thereby electrical stimulation of neuromuscular structures in the tissue by the electric fields is minimized.

Abstract: N-Methyldiprenorphine, useful as an opioid antagonist.

Abstract: Compounds of formula (I) in which X, Y, R1, R2, n, R3 and R4 have the meanings given in the specification, are useful as pro-drugs of peripheral phenolic opioid antagonists.

Abstract: A bipolar, plasma-generating electrosurgical apparatus and system wherein the return electrode is enclosed within an electrosurgical shaft, and the active electrode is located on the outside surface of the shaft such that in treating the tissue, the tissue is exposed to plasma generated on the active electrode, but is minimally exposed to electric fields generated between the active and return electrodes. Due to the configuration of the electrodes, electric fields generated between the electrodes are directed away from the target tissue and inwardly towards the return electrode within the shaft, thereby electrical stimulation of neuromuscular structures in the tissue by the electric fields is minimized.

Abstract: A bipolar, plasma-generating electrosurgical apparatus and system wherein the return electrode is enclosed within an electrosurgical shaft, and the active electrode is located on the outside surface of the shaft such that in treating the tissue, the tissue is exposed to plasma generated on the active electrode, but is minimally exposed to electric fields generated between the active and return electrodes. Due to the configuration of the electrodes, electric fields generated between the electrodes are directed away from the target tissue and inwardly towards the return electrode within the shaft, thereby electrical stimulation of neuromuscular structures in the tissue by the electric fields is minimized.

Abstract: A method is disclosed for clearing effusion from an ear. The method may include applying liquid to an ear canal, which is proximal to a perforated tympanic membrane, which is proximal to a middle ear containing effusion, applying an ear device to seal and pressurize the liquid inside the ear canal, the ear device regulating the amount of pressure inside the ear canal, and inducing a Eustachian tube, which is distal to the middle ear, to open, which causes the fluid to displace the effusion into the Eustachian tube.

Abstract: A system and method for use in iontophoretic anesthesia of a tympanic membrane are disclosed. The system generally includes an earplug and an electrode device. The earplug includes at least one sealing member for sealing the earplug in an ear canal. The sealing member includes microholes which vent fluid above a certain pressure threshold. A headset may connect the earplug to a second earplug. The method involves using the system on a human or animal subject.

Abstract: A cleaning appliance includes a motor arranged to drive a fan for generating suction air flow and a cleaner head having a drivable agitator with a dedicated motor. The agitator drive motor has a selectively-operable switch and a resettable circuit breaker arranged such that, when the switch is activated, the circuit breaker is reset. A button actuates the switch and simultaneously resets the circuit breaker. When there is a blockage so that the circuit breaker trips out the motor, the user can reset the circuit breaker and restart the agitator motor by the simple act of depressing one button, thereby obviating the need for a separate control.

Abstract: A device for dilating an ostium of a paranasal sinus of a human or animal subject may include: a handle; an elongate shaft having a proximal end coupled with the handle and extending to a distal end; a guidewire disposed through at least a portion of the shaft lumen; a dilator having a non-expanded configuration and an expanded configuration; and a slide member coupled with at least one of the guidewire or the dilator through the longitudinal opening of the shaft for advancing the guidewire and/or the dilator relative to the shaft.

Abstract: Systems and methods for treating paranasal sinuses in a head of a patient include, for example, forming an opening through a canine fossa into a maxillary paranasal sinus and performing a procedure such as a balloon catheter dilation of the maxillary sinus ostium. In some embodiments, one or more procedures other than a balloon dilation procedure may be performed. In some embodiments, a combination of balloon dilation and one or more other procedures may be performed. Various approaches involve employing medical devices to accomplish alternative treatment modalities as well as taking alternative routes to the interventional site.

Abstract: An apparatus, including: a light source; a controller configured, in response to the occurrence of a first event involving the apparatus, to control the light source to produce a first, time-varying, illuminative effect that varies between maxima and minima of illumination intensity over a period of time following the occurrence of the first event, wherein the variation in the first illuminative effect is indicative to a user that the first event has occurred; and the controller being further configured, in response to the occurrence of a second event involving the apparatus, to control the light source to produce a second, time-varying, illuminative effect that varies between maxima and minima of illumination intensity over a period of time following the occurrence of the second event, wherein the variation in the second illuminative effect is indicative to a user that the second event has occurred.

Abstract: A system and method for use in iontophoretic anesthesia of a tympanic membrane are disclosed. The system generally includes an earplug and an electrode device. The earplug includes at least one sealing member for sealing the earplug in an ear canal. The method involves using the system on a human or animal subject.

Abstract: A variable direction of view endoscope is positionable at desired locations within the ear, nose, throat, paranasal sinuses or cranium to accomplish visualization. A method of use includes introducing the variable direction of view endoscope into a nasal cavity with the endoscope adjusted to a first direction of view between about 0 degrees and about 15 degrees relative to a longitudinal axis of the endoscope. A therapeutic device is introduced into the nasal cavity and the endoscope is adjusted to a second direction of view directed toward the sinus opening or passageway. The method also includes advancing the therapeutic device into or through the sinus opening and viewing at least one of the sinus opening or passageway or the therapeutic device using the endoscope adjusted to the second direction of view.

Abstract: Devices and methods for locating sinus ostia and positioning a guide wire within the sinus ostia. The subject devices comprise a shaft having a distal end, a proximal end, a curved region located between the distal and proximal ends, and an interior channel, an extensible and retractable guide wire movably mounted within the interior channel and a probe tip joined to the guide wire. Certain devices further include expandable portions for engaging and treating body anatomy.

Abstract: Information is stored in a data pattern. The data pattern includes an identity table, a version table that includes at least one reference to the identity table, and an audit table that includes at least one reference to the version table. The identity table stores information identifying the information. The version table stores version information identifying one or more versions of the information identified in the identity table. The audit table stores audit information identifying when each of the one or more versions of the information was modified. The audit table may also store effectiveness information identifying when each of the one or more versions of the information is in effect.

Abstract: A method and system for providing a consistent flow documents and data content across different organizational units of a company or agency where the documents and data come from different enterprise systems and data stores but are related to linked processes that share models for organizing the content in the business context and in a format that enables a user to relate the content to the process step or steps they are performing. The system includes a network service that enables a configuration utility to automatically discover the objects and metadata and provides for a mapping of selected fields of the metadata to regions displayed in the user interface view with provision for filtering the data by mapping selected fields to a user input form. Thereby, a business analyst can create solutions without writing and maintaining complex program logic for each combination of presentation environment, enterprise system and data store.