Patents by Inventor Thomas Jenuwein

Thomas Jenuwein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chromatin regulator genes
    Patent number: 7252968
    Abstract: The invention concerns the deregulation of the chromatin-regulator genes which have a SET domain, such deregulation being of importance in certain cancer conditions. These genes can be used in the diagnosis and therapy of such conditions.
    Type: Grant
    Filed: February 9, 2004
    Date of Patent: August 7, 2007
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thomas Jenuwein, Götz Laible, Donal O'Carroll, Frank Eisenhaber, Stephen Rea
  • Mammalian SUV39H2 proteins and isolated DNA molecules encoding them
    Patent number: 7052889
    Abstract: Murine and human Suv39h2 polypeptide and DNA molecules encoding them. Suv39h2 is a novel member of the Suv3-9 gene family. Suv39h2 is a novel component of meiotic higher order chromatin. It has histone methyltransferase activity and is required, in combination with Suv39h1, for male gametogenesis. Suv39h2 can be used in screening methods to identify modulators of its methyltransferase activity, which are useful in cancer therapy and for male contraception.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: May 30, 2006
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thomas Jenuwein, Donal O'Carroll, Stephen Rea
  • Chromatin regulator genes
    Publication number: 20050089880
    Abstract: The invention concerns the deregulation of the chromatin-regulator genes which have a SET domain, such deregulation being of importance in certain cancer conditions. These genes can be used in the diagnosis and therapy of such conditions.
    Type: Application
    Filed: February 9, 2004
    Publication date: April 28, 2005
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Thomas Jenuwein, Gotz Laible, Donal O'Carroll, Frank Eisenhaber, Stephen Rea
  • Chromatin regulator genes
    Patent number: 6689583
    Abstract: The invention concerns the deregulation of the chromatin-regulator genes which have a SET domain, such deregulation being of importance in certain cancer conditions. These genes can be used in the diagnosis and therapy of such conditions.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: February 10, 2004
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thomas Jenuwein, Götz Laible, Donal O'Carroll, Frank Eisenhaber, Stephen Rea
  • Method for identifying compounds altering higher-order chromatin-dependent chromosome stability
    Publication number: 20030157532
    Abstract: A method for identifying compounds that alter higher order chromatin dependent chromosome stability is based on determining the compounds' ability to modify a methyltransferase with Suv39h-like methyltransferase activity. The identified compounds are useful in therapy, in particular the therapy of human cancer and for contraception.
    Type: Application
    Filed: December 20, 2002
    Publication date: August 21, 2003
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Thomas Jenuwein, Stephen Rea, Frank Eisenhaber, Donal O'Carroll
  • Mammalian Suv39h2 proteins and isolated DNA molecules encoding them
    Publication number: 20030104599
    Abstract: Murine and human Suv39h2 polypeptide and DNA molecules encoding them. Suv39h2 is a novel member of the Suv3-9 gene family. Suv39h2 is a novel component of meiotic higher order chromatin. It has histone methyltransferase activity and is required, in combination with Suv39h1, for male gametogenesis. Suv39h2 can be used in screening methods to identify modulators of its methyltransferase activity, which are useful in cancer therapy and for male contraception.
    Type: Application
    Filed: November 25, 2002
    Publication date: June 5, 2003
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Thomas Jenuwein, Donal O'Carroll, Stephen Rea
  • Method for identifying compounds altering higher-order chromatin-dependent chromosome stability
    Patent number: 6555329
    Abstract: A method for identifying compounds that alter higher order chromatin dependent chromosome stability is based on determining the compounds' ability to modify a methyltransferase with Suv39h-like methyltransferase activity. The identified compounds are useful in therapy, in particular the therapy of human cancer and for contraception.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: April 29, 2003
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thomas Jenuwein, Stephen Rea, Frank Eisenhaber, Dónal O'Carroll
  • Method for identifying compounds altering higher-order chromatin-dependent chromosome stability
    Publication number: 20020081638
    Abstract: A method for identifying compounds that alter higher order chromatin dependent chromosome stability is based on determining the compounds' ability to modify a methyltransferase with Suv39h-like methyltransferase activity. The identified compounds are useful in therapy, in particular the therapy of human cancer and for contraception.
    Type: Application
    Filed: June 8, 2001
    Publication date: June 27, 2002
    Inventors: Thomas Jenuwein, Stephen Rea, Frank Eisenhaber, Donal O'Carroll
  • Mammalian SUV39H2 proteins and isolated DNA molecules encoding them
    Publication number: 20020039776
    Abstract: Murine and human Suv39h2 polypeptide and DNA molecules encoding them. Suv39h2 is a novel member of the Suv3-9 gene family. Suv39h2 is a novel component of meiotic higher order chromatin. It has histone methyltransferase activity and is required, in combination with Suv39h1, for male gametogenesis. Suv39h2 can be used in screening methods to identify modulators of its methyltransferase activity, which are useful in cancer therapy and for male contraception.
    Type: Application
    Filed: June 8, 2001
    Publication date: April 4, 2002
    Inventors: Thomas Jenuwein, Donal O'Carroll, Stephen Rea