Patents by Inventor Thomas Jerussi

Thomas Jerussi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide
    Publication number: 20060216799
    Abstract: Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
    Type: Application
    Filed: May 3, 2006
    Publication date: September 28, 2006
    Applicant: SEPRACOR INC.
    Inventors: Thomas Jerussi, Qun Fang, Mark Currie
  • Methods of using derivatives of (-)-venlafaxine
    Publication number: 20060199861
    Abstract: Methods of preparing, and compositions comprising, derivatives of (?)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Application
    Filed: May 5, 2006
    Publication date: September 7, 2006
    Inventors: Thomas Jerussi, Chrisantha Senanayake, Nandkumar Bhongle
  • Salts of (-)-O-desmethylvenlafaxine
    Publication number: 20060199860
    Abstract: Methods of preparing, and compositions comprising, derivatives of (?)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Application
    Filed: May 5, 2006
    Publication date: September 7, 2006
    Inventors: Thomas Jerussi, Chrisantha Senanayake, Nandkumar Bhongle
  • Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide
    Publication number: 20060128993
    Abstract: Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
    Type: Application
    Filed: January 24, 2006
    Publication date: June 15, 2006
    Applicant: SEPRACOR INC.
    Inventors: Thomas Jerussi, Qun Fang, Mark Currie
  • Methods of making and using N-desmethylzopiclone
    Publication number: 20060025418
    Abstract: The invention is directed to compositions comprising, and methods of using, racemic N-desmethylzopiclone, optically pure (+)-N-desmethylzopiclone, and optically pure (?)-N-desmethylzopiclone in the treatment and prevention of diseases and conditions in mammals. The invention is further directed to novel methods of preparing N-desmethylzopiclone, optically pure (+)-N-desmethylzopiclone, and optically pure (?)-N-desmethylzopiclone.
    Type: Application
    Filed: September 20, 2005
    Publication date: February 2, 2006
    Inventors: Thomas Jerussi, Chrisantha Senanayake, Paul Rubin, Yaping Hong, Roger Bakale, Tingjian Xiang, Fran McConville
  • Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide
    Publication number: 20060014982
    Abstract: Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
    Type: Application
    Filed: September 7, 2005
    Publication date: January 19, 2006
    Applicant: SEPRACOR INC.
    Inventors: Thomas Jerussi, Qun Fang, Mark Currie
  • O-desmethylvenlafaxine and methods of preparing and using the same
    Publication number: 20050197392
    Abstract: Methods of preparing, and compositions comprising, derivatives of venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Application
    Filed: March 29, 2005
    Publication date: September 8, 2005
    Inventors: Thomas Jerussi, Chrisantha Senanayake
  • Imidazo[1,2-a] pyridine anxiolytics
    Publication number: 20050171144
    Abstract: Imidazo[1,2-a]pyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed.
    Type: Application
    Filed: October 28, 2004
    Publication date: August 4, 2005
    Applicant: Sepracor Inc.
    Inventors: Kevin Fang, Paul Grover, Thomas Jerussi