Patents by Inventor Thomas Joachim Landewald Rammeloo

Thomas Joachim Landewald Rammeloo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystallization procedure for obtaining canagliflozin hemihydrate crystals
    Patent number: 10323025
    Abstract: The present invention relates to an improved crystallization procedure to obtain canagliflozin hemihydrate crystals having a narrow particle size distribution by removing a small part of the crystalline suspension in the crystallization vessel from said vessel and subjecting said part to particle size reduction of the formed crystals followed by heating and reintroducting said part of the crystalline suspension again in the crystallization vessel which is kept within a specific temperature range.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: June 18, 2019
    Assignee: Janssen Pharmaceutica NV
    Inventors: Ruben De Keyser, Stijn Laps, Thomas Joachim Landewald Rammeloo, Koen Johan Herman Weerts
  • CRYSTALLIZATION PROCEDURE FOR OBTAINING CANAGLIFLOZIN HEMIHYDRATE CRYSTALS
    Publication number: 20190002449
    Abstract: The present invention relates to an improved crystallization procedure to obtain canagliflozin hemihydrate crystals having a narrow particle size distribution by removing a small part of the crystalline suspension in the crystallization vessel from said vessel and subjecting said part to particle size reduction of the formed crystals followed by heating and reintroducting said part of the crystalline suspension again in the crystallization vessel which is kept within a specific temperature range.
    Type: Application
    Filed: December 20, 2016
    Publication date: January 3, 2019
    Applicant: Janssen Pharmaceutica NV
    Inventors: Ruben De Keyser, Stijn Laps, Thomas Joachim Landewald Rammeloo, Koen Johan Herman Weerts
  • Crystallisation process for 1-(?-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl] benzene
    Patent number: 8772512
    Abstract: The present invention relates to a crystallization procedure to obtain 1-(?-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl] benzene hemihydrate crystals having a narrow particle size distribution and improved flowability, bulk and tap density properties.
    Type: Grant
    Filed: July 8, 2010
    Date of Patent: July 8, 2014
    Assignee: Janssen Pharmaceutica NV
    Inventors: Thomas Joachim Landewald Rammeloo, Ruben De Keyser, Gustaaf Jozef Petrus Schildermans
  • CRYSTALLISATION PROCESS FOR 1-(BETA-D-GLUCOPYRANOSYL)-4-METHYL-3-[5-(4-FLUOROPHENYL)-2-THIENYLMETHYL] BENZENE
    Publication number: 20120108824
    Abstract: The present invention relates to a crystallisation procedure to obtain 1-(?-D- glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl] benzene hemihydrate crystals having a narrow particle size distribution and improved flowability, bulk and tap density properties.
    Type: Application
    Filed: July 8, 2010
    Publication date: May 3, 2012
    Inventors: Thomas Joachim Landewald Rammeloo, Ruben De Keyser, Gustaaf Jozef Petrus Schildermans
  • Methods for the preparation of hexahydrofuro[2,3-B]furan-3-ol
    Patent number: 8153829
    Abstract: Methods for the preparation of hexahydrofuro[2,3-b]furan-3-ol and especially its enantiomer (3R,3aS,6aR) hexahydrofuro[2,3-b]furan-3-ol, as well as certain novel intermediates for use in such methods are disclosed.
    Type: Grant
    Filed: November 9, 2007
    Date of Patent: April 10, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Sébastien François Emmanuel Lemaire, Andras Horvath, Wim Albert Alex Aelterman, Thomas Joachim Landewald Rammeloo
  • METHODS FOR THE PREPARATION OF HEXAHYDROFURO[2,3-b]FURAN-3-OL
    Publication number: 20100094028
    Abstract: Methods for the preparation of hexahydrofuro[2,3-b]furan-3-ol and especially its enantiomer (3R,3aS,6aR) hexahydrofuro[2,3-b]furan-3-ol, as well as certain novel intermediates for use in such methods.
    Type: Application
    Filed: November 9, 2007
    Publication date: April 15, 2010
    Applicant: TIBOTEC PHARMACEUTICALS LTD
    Inventors: Sébastien François Emmanuel Lemaire, Andras Horvath, Wim Albert Alex Aelterman, Thomas Joachim Landewald Rammeloo